CytoSorbents Corporation (CTSO)

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Invitation to Masterclass Satellite Symposia on Nov 28th!
Satellite symposia organized by the International Fluid Academy (IFA) in collaboration with Baxter, Pulsion Medical Systems, Maquet Getinge, Fresenius-Kabi and Cytosorbents
6. Masterclass Satellite Symposium (): Fix the leaky bucket to prevent fluid overload - How Cytosorb stops capillary leakage
Presenter: Dr. Karl Traeger, MD, PhD - Professor and Head of Cardiosurgical Intensive Care Unit, Cardiac Anaesthesia Department, University Hospital Ulm, Ulm, Germany
Time: Friday, 28. November 2014, 14:00 pm (CEST)
Location: Room Lijn

Karl Traeger: Bioprofile

In this Session you will learn about:
The overproduction of cytokines by the immune system, often called “cytokine storm”, is a hallmark of many life-threatening illnesses seen in the ICU such as severe sepsis and septic shock
A cytokine storm can be toxic, causing direct cell death, massive capillary leakage, severe inflammation, and a cascade of events that can ultimately lead to shock and multiple organ failure
At the heart of the Cytosorb® technology is a biocompatible, highly porous polymer designed to capture and adsorb cytokines in the ~10-50 kDa “cytokine sweet spot” where most cytokines reside
The goal is to reduce toxic cytokine levels to prevent or mitigate organ failure and immune suppression, and to seal the capillary leak, thereby improving clinical outcome
Key-learning issues during this lecture:
Recognize the role of uncontrolled immune response for clinical changes of vascular tone, hemodynamic changes, capillary permeability, organ dysfunction
Recognize the parameters of proinflammatory cytokines and the course of their activation in the context of inflammatory diseases
Review different approaches of blood purification for modulation of cytokine levels
Learn the effects of bead adsorber technology for cytokine removal
Recognize different indications for hemadsorption therapy

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