Innovation Pharmaceuticals Inc (IPIX)

[KMBJN]

Kevetrin doesn't really activate the TP53 gene, rather the gene product p53 (protein of 53 kDa size), via multiple mechanisms. We are not modifying any genes.

Gene therapy would be, as you said, insertion or knockout of genes, or modification of (mutated) genes. Human clinical trials for gene therapy have to go through additional precautions, such as staggered starts, the recombinant DNA advisory committee, and other.

http://osp.od.nih.gov/office-biotechnology-activities/biomedical-technology-assessment/hgt/rac

Gene therapy companies include: SGMO, BLUE, KITE, etc... but not CTIX. Here is a list of all the Gene Therapy trials that have occurred in the US:

http://osp.od.nih.gov/sites/default/files/resources/PROTOCOL_0.pdf