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Re: iwfal post# 183315

Wednesday, 10/29/2014 2:47:04 PM

Wednesday, October 29, 2014 2:47:04 PM

Post# of 252358
SRPT:

Well, the duplication didn't help but I was disenchanted before that.

I really did not like the quality of their Western blots. I would not accept that from a summer undergrad, let alone a biotech company. That made me very skeptical about the general quality of their work, and whether it was trustworthy as you usually save your "best" image for presentation.

Also, the "% of fibers that are dystrophin positive" was very hokey and could easily be manipulated when doing immunofluorescence.

In effect, I found none of their dystrophin data remotely comforting. That was a dealbreaker for me, because I actually believe in dystrophin as a valid surrogate.

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