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Re: robi-1-kenobi post# 102348

Sunday, 10/19/2014 4:10:38 PM

Sunday, October 19, 2014 4:10:38 PM

Post# of 146301
My thought also was multiple versions, which Dr. Seymour has alluded as well as an attempt at a manipulation of glycan caps, a complex chemical structure and triggers for release.

Also, considering the securing of a BSL-4 facility and its preparation for Ebola studies, as well as the preparation of cultures and animal subjects, 3 to 4 months could be in the range of time required. So, 3 to 4 months to create and test in house several variations would not really delay BSL-4 lab studies. The question is whether or not the EbolaCide versions will be ready in that time.

Perhaps (my speculation) they are adding candidates with additional alternating ligands to activate the glycan caps on the cholesterolase receptors to enable their specific NPC1 ligand to bind to NPC1 in a 2-step process. I noticed in initial releases they talked about ligand in the singular, but Dr. Seymour also emailed and Nanopatent also excerpted literature on the glycan caps.


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