Pacific Biosciences of California Inc (PACB)

[Paulieme]

"this report undermines PacBio"?
NOT!!!
It is actually good news for PacBio (and any other noisy long read technology like nanopore). Availability of better algorithms means researchers will need less computing power in assembling the reads. So, that makes the sequencing technology more usable, whereas the processing time used to be a big concern in the past.

One caution, however, is that the new paper used both PacBio and Illumina reads, whereas the 405,000 CPU hour reporting was based on PacBio only. Therefore, 6 hours vs 405K hours is not an apple-to-apple comparison. A better comparison would be based on what Gene Myers reported in his DALIGN paper.

http://www.homolog.us/blogs/blog/2014/07/28/in-dalign-paper-gene-myers-delivers-a-major-blow-to-his-biggest-competitor/