Saturday, October 11, 2014 6:28:35 AM
Ebola Treatment Maker Takes New Steps to Increase Production
"Another option to increase supplies: Mapp said it is working with the Bill and Melinda Gates Foundation and a pharmaceutical company that it declined to name to use animal cells instead of tobacco plants to manufacture ZMapp. Mapp said the partners will use cells derived from the ovaries of Chinese hamsters, a cell type known by the acronym CHO that is frequently used to produce proteins that can be turned into drugs."
http://online.wsj.com/articles/ebola-tr ... 1412951468
AVID
Studies Conducted With a Suspension CHOExpression System Resulted in Specific Feeds, Nutrient Concentration, and Optimized Process Parameters That Increased Titer by 10-Fold
" Avid Bioservices, Inc., a wholly owned subsidiary of Peregrine Pharmaceuticals, Inc., today announced that recent studies evaluating a new suspension Chinese Hamster Ovary (CHO) expression system identified several process parameters and a combination of feeds that significantly increased titer and productivity."
http://news.avidbio.com/press-releases/avid-bioservices-to-highlight-novel-methods-for-increasing-protein-expression-an-1100521
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