Now both title and body are updated, it is quite clear the front line trial is for accelerated phase only: Ponatinib - Frontline for Chronic Myeloid Leukemia (CML) in Accelerated Phase (AP) http://clinicaltrials.gov/ct2/show/NCT01570868?term=ponatinib&rank=3 As I had argued here while you insisted otherwise: http://investorshub.advfn.com/boards/replies.aspx?msg=105199692