Pacific Biosciences of California Inc (PACB)

[Paulieme]

Breakthrough study discovers six changing faces of ‘global killer’ bacteria
Issued by University of Leicester Press Office on 30 September 2014

"Every ten seconds a human being dies from pneumococcus infection making it the leading cause of serious illness across the globe." The University of Adelaide and scientists from Pacific Biosciences, and has for the first time shown a genetic switch that allows this bacterium to randomly change its characteristics into six alternative states.
http://www2.le.ac.uk/offices/press/press-releases/2014/september/breakthrough-study-discovers-six-changing-faces-of-2018global-killer2019-bacteria---- "Now that scientists have determined the methylation profiles with the PacBio® platform, it should be possible for other scientists to accurately assign the pathogen to its specific phase. “Future studies must recognize the potential for switching between these heretofore undetectable, differentiated pneumococcal subpopulations in vitro and in vivo,” the authors note. “We believe these findings represent a new paradigm in gene regulation in bacteria and therefore are of great significance to the infectious disease field.”

http://blog.pacificbiosciences.com/2014/09/new-papers-detail-complexity-of.html?m=1