From Wells: **IMS data for Sovaldi were released for week ended 9/19/2014. **The week's total Sovaldi prescriptions were 5,943, a change of 1.78% vs. last week's 6,051, and the week's new Sovaldi prescriptions were 2,205, a change of 3.03% vs. last week's 2,274. **Plugging this into our proprietary Sovaldi projector, we believe U.S. Sovaldi sales could reach the following under these scenarios: (1) Base case secondary warehousing growth in new patient starts slows Q2Q3 then picks up Q4 (base case) $ 12.69B from $10.90B (2) Rapidly decaying Sovaldi new patient starts rest of year (bear case) $ 11.24B from $9.58B (3) Sovaldi new patient starts level off rest of year $ 11.64B from $10.02B (4) Weekoverweek NRx changes match those seen with Incivek+Victrelis at same point in launch $11.42B from $9.81B **WW Q3 2014 sales track at $3.71B (above FactSet consensus $2.97B), though we note this projection has been fluctuating somewhat week over week. **BOTTOM LINE: Our base case projects 2014 sales of $14-15B, as prescription trends were stronger than expected after Labor Day. We continue to believe, based in part from tracking survey data we have analyzed, that there remains significant warehousing ahead of the all-oral launch given potentially compressing Sovaldi+Olysio use, and while very early approval of sofosbuvir/ledipasvir is unlikely, the uptick postapproval will likely be substantial and drive continued stock momentum.