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Re: TheDane post# 70838

Friday, 09/26/2014 12:18:43 AM

Friday, September 26, 2014 12:18:43 AM

Post# of 403754
Hey TD, perhaps more interesting will be the change in tumor size, decrease serum tumor marker since these are more measurable/easier to understand than p21 in fact one might want to correlate p21 to the other two secondary measures. I assumed the secondary data is only completed up to cohort 4 just assuming one starts at cohort 1 (or 0) and the data for p21 is only for 14 patients at very low doses. So it sounds to me that most of the data so far is to complete the primary objective safety and dose escalate. Blood samples are being stored for p21 testing later and perhaps serum marker which was mentioned with ovarian cancer. Just a thought..

I am an aquatic biologist/engineer I run experiments all the time (nothing at all like what CTIX is working with). But during an experiment I am not focused at all on analyzing data but rather on making sure everything goes as planned to complete the experiment. I finished a year long experiment 2 weeks ago now I have 1200 images and ~2000 frozen samples to go through. I wont know much about what happened during the experiment until I start to process those samples starting from the beginning and processing data in batches. Science is busy work I didn't really look at the images I took at the time other than making sure I took the picture correctly and saved it to file. The samples went straight in to the freezer.

Just say'in that just because K p1 is now 2 years old and we are not all rich because Leo filed for breakthrough for curing cancer or there was great information leaked out about the trial rather no one really know yet. They have not really started to analyze the data and are still on the primary objective- the experiment. Images and samples for the most part are stored away for later analysis they are not critical at this point.