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Re: TheDane post# 68756

Tuesday, 09/09/2014 11:04:14 PM

Tuesday, September 09, 2014 11:04:14 PM

Post# of 403595
This next cohort is a break from the escalation they have been following up to this moment. Someone correct me if I'm wrong but I believe previous cohorts have ranged from 35% to 50% increases, while this is 67%. Surely previous cohorts did not show grade 2 AEs, yet no cohort increased more than 50%. Maybe the first cohort with its problem set the parameters for the next 8 cohorts, and only now are they confident enough to escalate according to the original protocol guidelines.

If we had luciferin to compliment our luciferase, we too would be
bioluminescent and not have to worry about being swallowed by a
giant Cardinalfish

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