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Re: JG36 post# 98264

Monday, 09/08/2014 11:55:14 AM

Monday, September 08, 2014 11:55:14 AM

Post# of 146246

,... what reason do we have to believe they'll ever be able to make commercial quantities of the stuff once (if ever) Flucide is approved?



The simplest answer to this question is - another question.

If the old lab is only generally capable of gram-level syntheses (say less than 100 g/ batch) and the new facility is generally capable of Kg-level syntheses (say 4-5 Kg / batch) - how many small batches would need to be pooled in order to give 4-5 Kg of product?

Answer,.... >-40-50 small batches.

Assuming that the small and large batch syntheses take approximately the same time to assemble and QC/QA then one set of reaction vessels in the new facility can do 40-50x the material in the same time period.

Set up sets of reaction vessels in parallel - and the amount that can be made at the same time multiplies by the number of parallel reaction vessels.

The initial scaling into a larger vessel can take time and tweaking. Once that has been worked out - that lead time is gone.

I ask in Response:

What legitimate reason do we have to believe that NNVC will NOT be able to manufacture commercial quantities of the 'stuff' even BEFORE Flucide is approved?
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