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Re: biocqr post# 181556

Sunday, 08/31/2014 11:31:48 AM

Sunday, August 31, 2014 11:31:48 AM

Post# of 251692
NVS—Short NEJM video on the MoA of LCZ696 and the K-M curves from the PARADIGM-HF study:

http://www.nejm.org/action/showMediaPlayer?doi=10.1056/NEJMoa1409077&aid=NEJMoa1409077_attach_1

Valsartan, one of the two constituent drugs in LCZ696, is the generic name for Diovan, which was NVS’ largest-selling drug before it went off-patent in 2012.

David Epstein, NVS' head of pharmaceuticals, said on the 2Q14 CC that sell-side analysts are under-estimating the commercial potential of LCZ696, which is the kind of public remark that NVS almost never makes.

“The efficient-market hypothesis may be
the foremost piece of B.S. ever promulgated
in any area of human knowledge!”

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