NanoViricides Inc. (NNVC)

[changes_iv]

Hopefully this could be used to curb the outbreak...they may have doses for up to 20,000 patients.

Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model

Highlights

• T-705 suppressed replication of Zaire EBOV by 4 log units in cell culture.
• Mice lacking the type I interferon receptor (IFNAR-/-) were used as in vivo model.
• In this model, T-705 administration prevented a lethal outcome.
• Treatment was effective even if initiated at day 6 post infection.

Abstract

Outbreaks of Ebola hemorrhagic fever in sub-Saharan Africa are associated with case fatality rates of up to 90%. Currently, neither a vaccine nor an effective antiviral treatment is available for use in humans. Here, we evaluated the efficacy of the pyrazinecarboxamide derivative T-705 (favipiravir) against Zaire Ebola virus (EBOV) in vitro and in vivo. T-705 suppressed replication of Zaire EBOV in cell culture by 4 log units with an IC90 of 110 µM. Mice lacking the type I interferon receptor (IFNAR-/-) were used as in vivo model for Zaire EBOV-induced disease. Initiation of T-705 administration at day 6 post infection induced rapid virus clearance, reduced biochemical parameters of disease severity, and prevented a lethal outcome in 100% of the animals. The findings suggest that T-705 is a candidate for treatment of Ebola hemorrhagic fever.



Ebola has no cure, no medical treatment—and in this deadly West Africa outbreak, doctors can only isolate victims and find those they had come into contact with to track the virus' spread.

Misinformation is running rampant in the countries that have been affected. Scores of newspapers urged residents of Liberia to "Burn all bodies." A pastor who claimed to have a cure for Ebola prompted Nigeria to decree that anyone spreading similar scams could face jail time. Street protests broke out in Kenema, Sierra Leone, when angry crowds attempted to burn down the city's Ebola treatment center in an effort to eradicate the virus.

To make it clear: There is no cure for Ebola.

Read more:
http://www.thewire.com/global/2014/08/why-there-may-never-be-a-cure-for-ebola/375452/

We don't have a cure for Ebola at NanoViricides, Inc. but we likely have the most low toxicity, effective (able to bind to the Ebola virus) and fast acting anti-viral nanoviricides that will destroy Ebola virus structures, in the trillions, in a matter of hours. To paraphrase Dr. Seymour, CEO of NanoViricides, Inc.,...yes, but more news are forthcoming!

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Non one other than NNVC bashers are talking about dropping FluCide tox studies in favor of EbolaCide. Tox studies for FluCide are advancing and are essential for EbolaCide.

Under 505b, tox for FluCide becomes tox for everything that follows. For the second tox following FluCide, they will only need to show bioequivalence, that is, a bridge study would be required to demonstrate that a system processes EbolaCide, DengueCide, X-Cide, in the same way as FluCide. Since FluCide will most probably already be in clinical trials, the second and maybe third X-Cide for clinical trials will need only a bridge study in Phase 1 to advance to Phase 2/3, again that would be an abbreviated PK study showing bioequivalence in processing versions of nanomicelles. ~ BigKahuna

...It's easier to sell the stock and put the money into the bank for nervous people like the elderly and the Yuppie who needs college funds. THAT'S WHO THE PACK OF SHORTS PRAY ON AND DEPEND ON. They bet on a stock to go down-not up! Understand? And they have just as much money and risk as you. But they have the edge of fear, lies, falsehoods to post and prey on the nervous. Longs don't have that. ~ jpinelli

http://www.hotstockmarket.com/t/44363/all-about-bashers
More: http://shockertrades.blogspot.com/2012/04/bashers-handbook.html