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Monday, 08/04/2014 4:10:41 AM

Monday, August 04, 2014 4:10:41 AM

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UA Heart Surgeon Dr. Zain Khalpey Receives Grant to Understand Healing Power of Stem Cells

Dr. Zain Khalpey Receives Grant to Understand Healing Power of Stem Cells

Here's some recent news that slipped passed my radar. If you remember, Dr. Zain Khalpey is the heart surgeon who was the principle investigator of the recent case study which was published in the American Journal of Medicine at the beginning of this year.

First in Man: Adipose-derived Stromal Vascular Fraction Cells May Promote Restorative Cardiac Function

-"As a last resort intervention for the patient's dysfunctional heart, 100 million adipose-derived stromal vascular fraction cells were delivered via localized intramyocardial injection (left apex), and 200 million adipose-derived stromal vascular fraction cells were delivered systemically via intravenous injection."

-"He had significant left ventricular systolic dysfunction (ejection fraction, 20%) with a thinned, akinetic inferolateral segment."

-"Within 7 days of the procedure, transesophageal echocardiography was performed to evaluate recovery of the patient's left ventricular function. His ejection fraction improved to 35% with recovery in the contractility of the previously akinetic inferolateral segment."

This research conducted by Dr. Zain Khalpey on this 73 year old patient using intellicell's technology to harvest stromal vascular fraction cells for treatment is simply astounding. Keep in mind that a normal range for ejection fraction of a healthy individual is 55-70% and typically is 58%. This patient had an EF of 20% prior to treatment with intellicells SVFC's and 7 days post treatment had an EF of 35%. This represents an improvement of 75%. Also, the patient had recovery in contractility of an area of the heart that was without movement prior to the SVFC treatment.

It appears Dr. Khalpey's newest research for which he has received a grant will be conducted to support his research toward understanding the mechanisms of how stem cell therapy works and how to maximize its potential for repairing damaged hearts.

-“We expect this research will provide important information on the potential of stem cells as mitochondrial donors with better mechanistic understanding of how mitochondria work. We hope that our clinical trials with stem cells in patients with heart failure and with mechanical heart-assist devices will surpass results seen in the field thus far.”

I think we can expect to see more news in the near future from all the great reasearch that Dr. Khalpey has been conducting on stem cells.


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