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Re: farrell90 post# 64287

Sunday, 08/03/2014 11:13:50 PM

Sunday, August 03, 2014 11:13:50 PM

Post# of 403752
Hi Farrell90, Seems like he has not updated his LinkedIn page since there is no reference to Polymedix which I thought was after his AMAG work. I agree with you/CallMeCrazy is appears he has been retained as a consultant with regards to Brillicidin. That said, I hope they also use his knowledge for the other Polymedix drugs that we acquired since it would make sense (although I could be dead wrong) that he would have been intimately involved in their initial testing as well. Would hate to see another company gobble him up and we could not use him as a consultant, it would boil down to what clauses he put in his contract. I stumbled across the info when researching "defensing mimetics" and was a bit uncomfortable with the fact that the company he works for, ioGgenetics, has a drug under development that would appear to be a competitor to Brillicidin. The info from their web page states:

"IOG-101 s designed to treat Staphylococcal infections including MRSA. It is targeted to enter into Phase 1 for ABSSSI (acute bacterial skin and skin structure infections) in 2015. The MRSA global market size is about $8 billion and current antibiotics continue to develop resistance. This product is clearly differentiated from current marketed products with minimum dosing/duration of administration compared to current products due to its distinguished mechanism of action. It has no/low toxicity and targeted delivery effective at nanomolar level based on in vitro and in vivo data to date. The preclinical in vivo data in animals is showing great promise for both therapeutic and prophylactic applications – offering significant benefit to the patient, as well as to the healthcare system in reducing hospital costs. Since this product can be developed for multiple indications, including pre-surgery prophylaxis, it has block buster potential."

It's notable that they are way behind us in development though.