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breezy1

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breezy1

Re: Citrati post# 105195

Monday, 07/21/2014 3:51:12 PM

Monday, July 21, 2014 3:51:12 PM

Post# of 130513
Spinal cerebellar ataxia Any idea on Orphan Status
For example a statement of filing for Orphan

New indications: MANF's neuroprotective activity was confirmed in a model of stroke, together with a deeper understanding of its anti-apoptotic mechanism of action involving the unfolded protein response (3). A further expansion into the orphan space was enabled by MANF's rescue activity in a genetic model of spinal cerebellar ataxia
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