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Re: Couch post# 115335

Tuesday, 07/08/2014 5:24:52 PM

Tuesday, July 08, 2014 5:24:52 PM

Post# of 401906
BIO-MD™ Opioids: Abuse-resistant Opioid Prodrugs

Signature Therapeutics’ proprietary abuse-resistant opioid prodrug technology – the BIO-MD™ platform - is designed to improve the care of patients with chronic pain while reducing the human and economic costs associated with prescription opioid drug abuse. Our opioid prodrugs are chemically stable molecules that provide pain relief similar to currently approved opioid drugs. However, unlike commonly used opioid drugs, our prodrugs resist the usual extraction and tampering techniques used by addicts to abuse prescription opioid drugs via injection or snorting, as well as chewing and crushing. Administered intravenously, our opioid prodrugs do not release opioid and do not produce any appreciable opioid effects. Consequently, our opioid prodrugs offer the benefits of effective pain relief with a substantially reduced potential for abuse.

http://www.signaturerx.com/view.cfm/59/Abuse-Resistant-Opioids

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