US Stem Cell Inc (USRM)

[Dragon Lady]

"first ever combination stem cell trial in the world"?? "EVER"?? and "IN THE WORLD"???

Kinda a bold "claim" IMO, in the age of Google. Just plugged in "combination stem cell trial" into ole Google, and it took a fraction of a second to return numerous search results.

Just read the first one, which sure sounds like a "COMBINATION stem cell trial" to me? Maybe I'm missing something here?

http://isci.med.miami.edu/clinical-trials-research/trials

TAC-HFT II: Phase I/II Study of the Safety and Efficacy of Transendocardial Injection of Autologous Human Cells (Mesenchymal or the combination of MSC and Cardiac Stem Cells) in Patients with Chronic Ischemic Left Ventricular Dysfunction and Heart Failure Secondary to Myocardial Infraction.

I believe "MSC" is traditionally bone marrow stem cells if not mistaken, but also can derive from other areas too? So it's a COMBINATION of a MSC type of stem cell and cardiac stem cells. It's a phase I/II as noted.

Sure sounds like an existing, "combination" uh "stem cell" ole "trial" to me? That's just reading one, out of About 8,440,000 results (0.33 seconds) from Google for the search term, "combination stem cell trial"


Here, here's one more just for good measure. This one is clear back in 2010, and describes STEM CELL COMBINATION TRIALS/RESEARCH in very specific details:
International Archives of Medicine 2010, 3:5 :
http://www.intarchmed.com/content/3/1/5

"Stem Cell Combinations"
"We have previously published data from an end-stage patient suffering from dilated cardiomyopathy which underwent a profound improvement in ejection fraction after receiving a combination of cord blood expanded CD34 cells and placental matrix derived mesenchymal stem cells [136]. In the current case report we describe a patient with ischemia cardiomyopathy who received a combination of allogeneic CD34 cells and endometrial regenerative cells (ERC), a MSC-like population which has previously been demonstrated to possess higher growth factor production ability as compared to control MSC cells [31],...."

Well, maybe add one more just for the heck of it- since the PR "claim" didn't specify first ever "human trial" of a combined stem cell approach- here's a "study/trial" involving "Yorkshire Swine" (I'd take that to be a pig of some sort?) but it's a COMBINATION stem cell trial:
"Enhanced effect of combining human cardiac stem cells and bone marrow mesenchymal stem cells to reduce infarct size and to restore cardiac function after myocardial infarction.
http://www.ncbi.nlm.nih.gov/pubmed/23224061

Well, since Google's making it so easy, here's one more, this one for "multiple myeloma". It's from 1992, so it's a golden-oldie versus the FIRST EVER COMBINED statement, IMO.
"Low-risk intensive therapy for multiple myeloma with combined autologous bone marrow and blood stem cell support"

http://bloodjournal.hematologylibrary.org/content/80/7/1666?variant=short&sso-checked=1

"all 75 patients was 68%, with 12-month event-free and overall survival projections of about 85%. Using both bone marrow and PBSC together with GM-CSF, autotransplants are safe and appear effective in myeloma, especially when prior therapy had been limited to less than 1 year. ...."
(PBSC is peripheral blood stem cell) according to the research paper.

SEVENTY FIVE patients in a COMBINED STEM CELL "trial" in NINETEEN NINETY TWO, 1992.

"FIRST EVER COMBINATION STEM CELL TRIAL in THE WORLD"????