True. The pathogen has to be present in order to work on it. One cannot manufacture an avian virus however just like HIV strains some companies do have limited influenza A (H5N1). Would a company like GE? And if they do have source could they get close enough to producing a vaccine so that some time might be saved if a mutant strain of H5N1 shows up?
Now as for small pox that pathogen is attainable. Small Pox is still on the bio-terror list is it not?
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