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Thursday, 06/05/2014 6:23:16 AM

Thursday, June 05, 2014 6:23:16 AM

Post# of 346418
PPHM on the news (sorry if already posted)...

http://www.marketnewscall.com/volume-alert-clovis-oncology-inc-nasdaqclvs-inovio-pharmaceuticals-inc-nysemktino-peregrine-pharmaceuticals-nasdaqpphm/1226736/

Peregrine Pharmaceuticals (NASDAQ:PPHM)’s shares climbed 2.63% to $1.76. The company on Apr. 23 announced the opening of an investigator-sponsored trial (IST) of its investigational immunotherapy bavituximab in combination with Bristol-Myers Squibb’s ipilimumab (Yervoy®), for the treatment of advanced melanoma. Bavituximab is an upstream immune checkpoint inhibitor that targets phosphatidylserine (PS), a highly immunosuppressive molecule exposed on cells that line tumor blood vessels and tumor cells. Preclinical data in a model of melanoma demonstrate that the combination of a bavituximab equivalent and ipilimumab yield enhanced anti-tumor activity compared to ipilimumab alone.
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