Rock Creek Pharmaceuticals Inc. (fka RCPIQ)

[Buddhahead]

Why inflammation leads to a leaky blood-brain barrier: MicroRNA-155 in Science Daily, June 2, 2014, Federation of American Societies for Experimental Biology

Summary:
"Until now, scientists have not known exactly how inflammation weakens the blood-brain barrier, allowing toxins and other molecules access to the brain. A new research report solves this mystery by showing that a molecule, called 'microRNA-155,' is responsible for cleaving epithelial cells to create microscopic gaps that let material through."

Excerpt:
"This study has the potential to be a game-changer in terms of how we treat neurological conditions and how we deliver drugs to the brain," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "Since it was first discovered, the Blood-Brain Barrier has always been a touch elusive. Now, after careful analysis, we are learning exactly how our bodies keep our brains safe and that microRNA-155 is a key player."


Article at:
http://www.sciencedaily.com/releases/2014/06/140602104749.htm