Rock Creek Pharmaceuticals Inc. (fka RCPIQ)

[Buddhahead]

NEW TOBACCO DERIVED SUPPLEMENT THAT REDUCES HASHIMOTO'S ANTIBODIES in Thyroid Pharmacist Blog, 11/17/2013

Excerpts:
"Hot off the presses, released on October 31st!

A brand new randomized, double-blind and placebo controlled study (this time in humans) followed a total of 146 patients with Hashimoto's for 3 months. Seventy of those patients were treated with Anatabine at a dose of 9-24mg per day, while the rest were treated with placebo.

The results showed a statistically significant reduction in Thyroglobulin antibodies (TgAb's) at weeks 4, 8, and 12. TgAb's reduced by an average of 46 points in the treatment group compared to a reduction by 4 points in the placebo group. 50% of patients reduced their antibodies by at least 25 points, while 25% reduced their TG antibodies by at least 100 points.

All of the patients in the study were euthyroid, meaning their TSH, T4, T3 were within range, either because they were taking levothyroxine or because they were in the early stages of Hashimoto's. Anatabine did not affect the levels of TSH, T4 or T3, but the patients who were taking levothyroxine seemed to have a greater reduction in antibodies that patients that were not.

Dizziness, nausea, tingling and headaches were some of the more common side effects."

"Surprisingly, the study did not find a statistically significant reduction in TPO antibodies. The authors of the study noted that TG antibodies are often the first antibodies to come down, followed by TPO antibodies and thought that perhaps more time was needed to see a statistically significant drop in TPO antibodies.

I found the same to be true in my case as well. My TG antibodies completely went away after my first lifestyle changes, but the TPO antibodies were slower to budge and took a longer time to reduce.

Additionally, while this was not shared in the study results, the manufacturer did share some preliminary results on TPO levels last January on their healthcare professional portal. One patient who was studied had an enormous drop in antibody levels after she took a dose of 0.12 mg/kg per day of anatabine for sixteen days. Her TPO antibodies reduced from 3655 IU to 300 IU.

I personally tried Anatabine for three months last year when I was in the middle of my root cause search and it actually lowered my TPO antibodies by about 50% (I didn't have anymore TG antibodies at the time).

What I found particularly interesting is that not everyone responds the same to Anatabine, the study noted that not everyone had a drop in TG antibodies, and some had a greater drop than others did. Of course, this makes sense as not everyone has the same root cause.

Article at:
http://www.thyroidpharmacist.com/blog/category/rock-creek-pharmaceuticals