Diva's Den

[Pyckstocks]

$PPCH - Propanc Scientific Findings Published in Peer Reviewed Cancer Journal
2014-05-21 22:49 ET
MELBOURNE, Australia, May 21, 2014 (GLOBE NEWSWIRE) -- Propanc Health Group Corporation (OTCQB:PPCH) ("Propanc Health Group", "Propanc" or "the Company"), a developmental stage healthcare company focused on new cancer treatments for patients with solid tumors, announced requests for information regarding the anti-cancer effects of its pancreatic proenzymes treatment ("PRP"), can be accessed via Cellular Oncology, a peer reviewed journal of the International Society for Cellular Oncology.

"We have received queries regarding the anti-cancer effects and mechanism of action of proenzymes, which we published last year in collaboration with our research partners," said James Nathanielsz, Chief Executive Officer of Propanc Health Group, "Publishing these findings was an important step to gain credibility within the scientific community who recognize the potential of pancreatic proenzymes as a treatment for metastatic cancer."

Propanc Health Group and its research partners identified that pancreatic proenzymes are able to suppress a long-silent, embryonic program reactivated by cancer cells, called the Epithelial Mesenchymal Transition, or EMT, by returning cancer cells back towards normal behavior. This is important because certain cancer cells develop traits such as motility, invasiveness and a resistance to readily dying. They also become "stem-cell" like and develop the ability to seed new tumors. This process, called metastasis, is responsible for approximately 90% of deaths from cancer.

"From our research we observed that pancreatic proenzymes enforce the re-entry of cancer cells into normal cellular pathways and as such, could represent an exciting new method of managing the disease process," said Dr Julian Kenyon, Chief Scientific Officer of Propanc Health Group, "We believe this small but significant step supports my initial observations from clinical practice that pancreatic proenzymes have the potential to prolong life and stop tumors from spreading, especially if we treat patients during earlier stages of the disease process".
It is anticipated a number of companies developing cancer stem cell therapies will be presenting at the upcoming 2014 ASCO (American Society of Clinical Oncologists) conference. New effective therapies against cancer stem cells attract significant attention due to their potential to control and inhibit metastatic cancer, an area where most cancer drugs often fail.
Propanc Health Group shares a joint intellectual property ownership arrangement with its research partner, the University of Bath, and patents are currently being prosecuted in countries around the world.

Propanc Health Group further aims to fast track the development of proenzyme related oncology products into clinical trials, initially for colorectal and pancreatic tumors. The world market for colorectal cancer is expected to reach $8.8 billion by 2020 and the global pancreatic cancer market is projected to exceed $1.6 billion by 2017, according to research reports.
The Company's scientific publication can be sourced from Cellular Oncology, July 2013, volume 36 (Issue 4), or purchased via the following link: http://link.springer.com/article/10.1007%2Fs13402-013-0134-8.