Mechanistically it seems to me that any of the RRMS drugs that work well (Tysabri is best) have a chance of delaying the onset of SPMS as they reduce the assault on the myelin and neurons. The reduction in the damage gives the body a chance for repair of the myelin. Tysabri has the best chance of delaying or reducing SPMS. (Of course, I don't have a science or medical background and guess a lot.)
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It is astonishing what foolish things one can temporarily believe if one thinks too long alone ... where it is often impossible to bring one's ideas to a conclusive test either formal or experimental. J.M. Keynes
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