Also I was unaware you could do puts and calls on OTCs. I will take that up on Real poet's thread.
I usually don't get too high a percentage of my portfolios tied up in them, but I almost always have calls or puts on one OTC or another.
Also, if I think an issue is overpriced, I generally prefer to buy puts, but I'm not terribly averse to shorting an OTC issue if I think the pullback might take too long to happen and my puts might expire worthless. Generally, I'm a bit too chicken to short very often, especially after being long an OTC from 5 to 10 last year, then shorting it at 12, only to ride it up to 17 while I was short. It took a while to come back down, but I did eventually cover at a small profit. Too small, actually. It dropped *WAY* down eventually, and now it's the one I've got the July calls on.