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Sunday, May 04, 2014 7:18:10 PM
The solstice heralds the beginning of summer in the Northern Hemisphere. In 2014, the solstice falls on June 21 at 6:51 A.M. EDT.
http://www.almanac.com/content/first-day-summer-summer-solstice
"Final results are expected by summer 2014. may rapidly lead to clinical application of the findings."
INTERIM PROGRESS REPORT
We have completed experiments in parkinsonian dyskinetic preclinical models. Results have so far suggested that co-administration of the A2A receptor antagonist Preladenant and the 5-HT1 receptor agonist Eltoprazine is highly effective in suppressing already established levodopa-induced dyskinesia, while easing the motor impairments in a model of Parkinson´s disease. This approach is currently being tested in MPTP-treated models. Further experiments in the initial model are also ongoing to address whether this treatment can prevent development of dyskinesia when given starting from the first levodopa dose. Final results are expected by summer 2014.
https://www.michaeljfox.org/foundation/grant-detail.php?grant_id=1030
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