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Post# of 251706
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Alias Born 05/05/2006

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Friday, 05/02/2014 12:22:33 AM

Friday, May 02, 2014 12:22:33 AM

Post# of 251706
ADHXF up 20% to $1.25, presenting 2 Phase 3 results at ASCO.
With 7 million float could have lots more upside. Very good preliminary results. Also trades on Toronto Exghange as AHX.TO so has good liquidity.


Sodium Thiosulfate (STS) Phase 3 Clinical Study Update

Adherex Announces Sodium Thiosulfate Clinical Study Update
~ Data have been submitted to ASCO 2014~

Adherex’s collaborator the Children’s Oncology Group (COG) posted top-line results from a Phase III trial of Adherex’s lead candidate STS to clinicaltrials.gov last week. The data are incomplete and no statistical analysis was performed. A full analysis of secondary endpoints such as event free survival and overall survival was not posted. Any interpretation should be limited until Adherex reports the full data, which is expected at the American Society of Clinical Oncology (ASCO) meeting in June 2014.

Posted Data, though Incomplete, is Encouraging. According to the posted results, the data regarding the frequency of patients with hearing loss is encouraging, and may support the primary endpoint after a full statistical analysis. The primary endpoint of the trial is hearing protection in pediatric oncology patients undergoing platinum-based chemotherapy.

The posted data show that out of 56 patients in the cisplatin arm of the study, 31 (55%) experienced hearing loss. For the 49 patients treated with STS and cisplatin, 14 (29%) experienced hearing loss. Information posted on the website is incomplete and final results may differ from those presented.

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