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Re: barcode27 post# 100334

Wednesday, 04/30/2014 9:31:27 AM

Wednesday, April 30, 2014 9:31:27 AM

Post# of 130505
Pfizer - and Lympro from barcode27 - Brilliant Find.

Must read this post.

Dear NIG Reviewer,

Several scientists who work in the area of Alzheimer's Disease and neurodegenertion at Pfizer
Inc are familar with the Pilot Study of the Lymphocyte Proliferation Test (LymPro Test) for the diagnosis of Alzheimer's
disease (AD)......

Current Milestones & Catalysts

LymPro

• Pilot clinical performance data (1H-14);
• Retrospective / prognostic 9 year patient record clinical study (1H-14)
• Clinical Performance studies to support CLIA registration (1H-14)
• Commercial Launch as a Laboratory-Developed Test (“LDT”) under CLIA (2H- 2014)

Eltoprazine

• Evaluate best indication for commercial development (1H/14)
• Initiate Phase 2b Clinical Trial (1H/14)
• MJFF Grant Funding (FY-14)

MANF

• Retinitis Pigmentosa: functional genetic mouse model (1H-14)
• Parkinson’s disease: CED delivery data w/Renishaw (1H-14)
• Preliminary systemic toxicology (PK/PD relationship) (1H-14)
• Wolfram Syndrome enablement (Diabetes)
• Functional Data (RP)