A single mutation can cause resistance and viral breakthrough if one or more drugs in an antiviral cocktail are vulnerable to the given mutation.
This is one reason IDIX’s IDX899, which requires multiple mutations to lose effectiveness in the HCV replicon, may turn out to be superior to Sustiva, which can be undone by a single mutation. Of course, GSK (IDIX’s new partner) will have to prove this in vivo.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”
Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.