Executive Officers  
 Craig Wheeler, CEO         350K shares   475K options 
 G. Venkataraman, CSO       458K shares   145K options 
 Steven Brugger, COO        263K shares   168K options 
 *John Bishop, SVP Pharma    41K shares   204K options 
 James Roach, CMO              0 shares   163K options 
 Richard Shea, CFO           28K shares   208K options 
 -- 
 Six executive officers   1,140K shares 1,363K options

 
 Non-executive directors  
 Peter Barrett (Atlas)    2,459K shares    77K options 
 John Clarke                 77K shares    77K options 
 Alan Crane (Polaris)       586K shares    54K options 
 Marsha Fanucci                0 shares    77K options 
 Peter Hutt                  67K shares   156K options 
 Robert Langer              970K shares    77K options 
 **Stephen Reeders (MVM)    483K shares    77K options 
 *Ram Sasisekharan          406K shares    77K options 
 *Bennett Shapiro             5K shares   109K options 
 Elizabeth Stoner              0 shares    30K options 
 -- 
 10 non-executive dirctrs 5,053K shares   811K options

 
 All officers/directors   6,193K shares 2,174K options