is...retired
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I am probably not asking my question very clearly. Paraphrasing IPIX gets 2 million from aspire if they sign an agreement for at least 10 million with pharma deal for one of IPIX drugs.
This does not make sense to me . Why does IPIX want 2 million from Aspire if they would be getting at LEAST 10 million from a deal
I am thinking LE is saying a deal is already all but signed for sep 30 .
Question - why would IPIX need 2 mil from aspire if they sign a deal for at least 10 million with a pharma ?
You got that right
well well well. welcome back.
I just bet you can find out how long it takes.
Yes I know but I am not going to tell. It might upset you.
I thought a 4 week check up after final dose would be the time of the "data lock". That should be some time ago since final dose waned of Dec i thought. Why drag it out?
OT I don't mind. the rules you know. Bio VIE
also found this interesting
Bioscience
Topic
Biotech
Topic
Denise Faustman
Person
Health Care
Industry
Hospitals
Topic
Pharmaceuticals
Topic
By Jessica Bartlett – Reporter, Boston Business Journal
5 hours ago
Research at Massachusetts General Hospital looks increasing like a long-term cure for type 1 diabetes, with a newly released study on Thursday showing patients have normal blood sugar levels eight years after a clinical trial.
In research published Thursday in journal npj Vaccines, patients who had been treated with the bacillus Calmette-Guerin (BCG) vaccine — an inexpensive, generic vaccine used around the world to prevent tuberculosis — had normal blood sugar levels eight years after the trial ended.
While it took three years for patients to see results from the vaccine, two doses of the drug spaced four weeks apart were still having a lasting impact eight years later.
“It’s kind of big news,” said Dr. Denise Faustman, director of the Massachusetts General Hospital immunobiology laboratory and principal investigator of the trial. “It’s the first trial showing (long-term reversal of diabetes), and more trials are on the way. But scientifically it’s pretty cool.”
The recently published study also details how the vaccine genetically alters the body’s white blood cells so they process glucose, making up for the pancreas’ inability to produce insulin to do the same. In type 1 diabetes — referred to in the past as juvenile diabetes — the immune system damages the pancreas and blocks the cells from producing insulin.
“It’s not only the discovery that something cheap in new cohorts brings down blood sugar, but why. We’ve discovered new pathways for lowering blood sugar,” Faustman said. “It’s an important discovery for the basic science of diabetes care. And by the way, we have a cheap BCG vaccine that seems to be doing it.”
Faustman has been working for over a decade on trials of the treatment, first in mice and then in humans. In addition to follow-ups with patients from the phase 1 clinical trial, a phase 2 clinical trial, which has been funded largely by support from the Iacocca Family Foundation, is ongoing. Faustman’s lab is still seeking the final $2 million of the $25 million cost.
The goal of the latest clinical trial is to replicate results from the first phase, as well as to analyze the dosing necessary to make the vaccine work quickly. The study isn’t accepting more patients, but Faustman encouraged patients to sign up when the trial is hopefully expanded.
News of the dramatic results has been trickling out as Faustman progresses work with the vaccine. Last year, Faustman discussed the research on the mechanism of the drug at the Scientific Sessions of the American Diabetes Association and in an interview with the Boston Business Journal. She said she waited until the eight-year clinical results were ready to publish the findings on how the drug works, in order to give more credence to the vaccine’s success.
Used in China, Africa and South America to vaccinate against TB, the BCG vaccine has been used 4 billion times over the last 100 years. Last year alone, 100 million doses of the vaccine were given to newborns. Because TB isn’t common in the U.S., children here do not receive the vaccine.
Faustman’s trial is one of several happening nationally on BCG. There is ongoing research into the drug's effect on multiple sclerosis in Italy, and on food allergies in Australia.
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The microorganism originates from the dirt. Faustman said the rise of autoimmune disorders, and the increase of food allergies and gluten intolerance, is tied to the fact that humans no longer interact with dirt in the way they once did.
Faustman has her sights set on more than just completing the phase 2 clinical trial. She hopes to also conduct a trial on the vaccine in children with type 1 diabetes, and to possibly make the drug available for right-to-try trials. There could also be future studies on whether the drug can work in type 2 diabetes.
“It’s a significant advance since the discovery of insulin, and it needs to be duplicated and replicated and expanded,” Faustman said.
The List
Largest Life Science Companies in Massachusetts
Ranked by Mass. employees
Rank Firm Mass. Employees
1
Sanofi Genzyme 5,000
2
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3
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BUSINESS PULSE POLL
What should be the next legislative priority on Beacon Hill?
Health care is the biggest spend. Lower those costs first.
Follow the governor’s lead and cut spending across the entire state budget so we can fund what’s important.
Our streets are choked and public transportation is awful. Offer a fair tax to raise revenue and fix these issues now.
Education is key to our economy, and it’s worth a new tax to improve our schoo
apologies. I answered a question about LE son's stock. There have been some good things happening there.
SP is moving up about one penny per day.
Before he was dead he was one of those responsible for the start of this company. His death does not diminish his support of Krishna Menon.
The stock has had mostly successful tests of the drugs. Another testament to Dr Frie and Dr Menon's smarts.
Only mistake imo is you know who.
Dr Frei would not be associated with a scam. Dr Menon was associated with Dr Frei at Dana Farber.
Could unchecked mgmt screw everything up trying to be smarter than anybody else? imo YES
I think many shareholders feel duped.
I wonder how those 3 guys (or gals) who put in 800K each some months back feel?
Plus he's gonna have Trump breathing down his neck as soon as he solves this months other problems.
you're sure about that?
I am sure you are correct but that info hasn't been given to us by Mr loquacious. B UP and B OM and B beating Dapto has been announced.
B UP is proven. B OM is better than anything else that is known right now. B beat dapto. So with all this shilly shallying over money thousands of suffering people continue to suffer.
no wonder that person chose to take a long time to retire. must have had an inkling of something.
where there is a will there is a way to communicate. wonder why IPIX mgmt is not doing it.
But you do know that LE placed an order for a commercial amount of B and you do know he then did as deal with Aspire to pay for it.
I am 86 will be 87 in August.
Is he the one that caused Dr Menon to lose a bundle?
imo it's time we heard from the wizard. LE
whatever happened to our faithful Canadian correspondent. does he not feel any responsibility?
How can upper mgmt be so inept as to maintaining a SP to reflect true value. B-UP and B-OM plus B beat dapto.
Change at the top is required. imo Leader not trusted by potential investors
And another thing. If he can take phone calls from shareholders or SA interviewers why can't he issue a weasel worded shareholder newsletter with the latest P delay?
I guess we can say there is no "quiet time".
My question and I think it is an obvious one "Why don't they have the results for P as of this LATE date?"
limo the person who was able to make the contact is again imo far too intelligent to have not thought of that. And the retirees absence is suspicious to me.
What in the H is going on?
HERE HERE!!!!
I will post "finally". could have been done a lot sooner with a lot less grief and a lot more benefit to the ill, suffering and dying.
unless of course he gets too cute by half and louses up the whole thing. I so wish Menon as in charge. Menon the humanitarian.
But not a CEO that can finalize a deal that would put us on track for solvency and ability to advance other prospects.
That is from the Inspire website that I am banned from. . Several people that post on IHUB can post on inspire
Could someone please check this out
Prurisol study/trial? - Inspire
https://www.inspire.com/groups/talk-psoriasis/discussion/prurisol-study-trial/
Mar 7, 2018 - 5 posts - ?3 authors
I was wondering if there will be another trial for Prurisol treatment as I hear it may be quite effective without harmful interactions or side effects.
I am banned so cannot do it.
PS I don't think Memorial day should play into anything except being a day like saturday or sunday when the market is closed.
Was that the end of December 2017 that the last P enrollee was dosed? If so that gives almost 5 months for follow ups and turning in the paper work. An explanation from mgmt is LONG overdue.
Also with all the good results expected you would think word would leak out. imo
We get excuses that are bunk imo
Wouldn't it be wonderful if patients in hospitals that unfortunately get a new infection demand B or those with HN cancers demand B-OM. President is just signing right to try law. About time the Leo's of this world are forced to do the humane thing. Never mind squeezing every nickel out of rotten big pharma.
if your results are accurate we would have heard by now imo
Just seems like something very good is about to be announced.
Anita is on linked. I believe she is dr Menon's daughter. Same with Kathleen Gibbs Secretarial School former employee. On linkedin
Cabel retired some time ago. I hope that he is back to emailing LE and giving us an update. Now that he is not working he should have lots of time to fill.