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Ask yourself this....
Who has the most to lose?
Sure the longs and not so longs may collectively lose a couple of million if it was a P&D however, I can name at least 2 Big Pharma that have a lot more to lose when $PMCB trial goes ahead.
Notice I said goes ahead, not completed. This is because once the tumors start shrinking and become operable due to CIAB's targeted application, the FDA will not want to put the patients on the other side of the test through therapy without it. If they did they would be negligent, since if the CIAB treated patients were able to get operations, they would be putting the control patients at certain risk of death by not receiving the same treatment; Result? FAST TRACK!
That is only the PC side of the argument. Insulin Big Pharma must be quaking in their boots that they will be next to fall to CIAB.
We are not talking about a few millions of greenbacks here but Billions!
Is it any wonder that the emissaries of SHORT are turning up here trying desperately to sink the ship before it can sweep all before it. There is no compassion for the sufferers of these conditions here and the fact the CIAB would give them hope and a real chance, just greed and fear. The extremely negative posts and the shorting of our stock can mean only one thing.... a concerted attack to either drive the pps down to where it can be comfortably absorbed by one of the Big Pharma companies or alternatively to drive the pps down to buy out a majority shareholding and control CIAB technology for themselves.
Big Pharma analysed the danger CIAB would pose to their operations and set in motion a two-pronged attack to bring it down. Own it or destroy it, we have seen and see the results of their efforts both in the shorting data and on this board
It's despicable considering lives are at stake, have you no conscience? Suppose one of your nearest and dearest was to get PC (God forbid). Would you not want them to have a chance at an operation?
Get thee GONE! Think about that as you crawl back to the hole from whence you came!
Go $PMCB! GO
Have a good flight and safe journey BioNewton.
Go $PMCB
One word for that ferenc......
Fear!
Go $PMCB!
and added to that..........
More details of the methodology....
Than what has been revealed so far, especially on the use of
Imaging Endpoints. Seems there has been a bit of a leak lol.
Go $PMCB
Agreed!
Go $PMCB
and I quote.....
Hi All, newbie here...
I have taken a medium position in this stock and expect to take a
larger one before the price gets too high.
You need to remember what President Trump is about and then you will see why this stock is bound to rise and rise.
Military spending is going to increase and President Trump has said that he wants to improve the US missile defence system.
In this situation it is not only the big defence companies that benefit but the small, specialised ones as well.
As President Trump increases spending on military options, expect this stock to rise and rise.
GO GO $GIGA
President Donald J Trump and the FDA....
An interesting article, and especially relevant to PMCB.
How Will Trump Change The FDA?
More than one way to smoke a ham, methinks!
GO $PMCB
But the fact that the Shareholders Call is going to be available to
the public...... why do that if its just more of the wait and see?
Nope, I reckon Mr W gonna drop a bomb on the bio med world in that call and he doesn't only want the shareholders and analyst to hear about it. He wants Joe Public to be fully cognizant.
Is it normal.....?
For a company to make a shareholder briefing available to the public?
One of the most telling things to me is that this what is going to happen. I do not think that Mr W is one to give so many people false hope,
both PC sufferers and shareholders.
That line alone tells me the pre-IND meeting went better than even Mr W hoped and he wants to shout it from the roof tops, just has to prepare for the bedlam that will come after is all, once everyone hears what he has to say.
I think Feb 07 2017 is going to be explosive!
Go $PMCB
Hi Bio, did you.....
....take a look?
Whats your opinion?
I think spread has a point. It's logical
I think spread has a point.
You are welcome.
Keeping Clinical Trial costs down....
An interesting and informative piece on how one micro-cap biopharma is going about reducing costs for the Phase III trials on one of their pipeline products (with FDA blessing!)
Pluristem Therapeutics Inc. (NASDSAQ:PSTI) To Begin CLI Phase III Trial Enrolling Only 250 Patients, With FDA Blessing
Opinions? Could PMCB be contemplating the same methodology?
ps. I have a position with this company also
Just one thing to add to that.....
GO $PMCB!
Why would he or wouldn't he?
It is not only talking about drugs per se.
Below is an extract which is taken from section 902 of FDASIA,the full document of which can be found here
I seriously believe the FDA told KW to.....
....go for Breakthrough Therapy Designation.
Given the impact that CIAB will have on the treatment on many
life-threatening conditions, I believe this is what KW is going to
tell us at the shareholder briefing. Everything about PMCB points to
this. Below is a short extract from a Q&A on BTD on the FDA website.
Loaded and Locked!
1,110,000 @ $3.50
Shorters beware PMCB not cheap!
GO $PMCB!
PMCB-US's investments and returns suggest it is betting on the future!
Great analysys on this page Capital Cube
It tells us what we already know..that PMCB is looking at
revolutionizing the future and all means are being bent to that end.
Great page for DD though and free to join with lots of metrics,
with the last two lines on the analysis reports very telling on
PMCB's focus.
So many Big Pharma companies nose are going to get put out of joint
by our "Upcoming" successful Clinical trial that they either
pay for licensing or fall to those that will. In the meantime they
are shorting our stock so if there is a buyout, out stock price is
not too high, thus making the buyout cheaper.
Keep the faith.... I know I will be.
ps. I am a type 2, live in the UK and I know this is going to work!!!!
GO $PMCB!!!! GO
Nail Struck on the Head!
My thoughts exactly.
Let the hoohah over the inauguration and the markets settle down a bit. Otherwise too much info from Waggs could get the impact
swallowed up by current events.
Go $PMCB!
Breakthrough Therapy Designation Possible?
There may be many more reasons to be cheerful if what is
postulated in the article in the link below is realised.
Pharmacyte Biotech Inc (OTCMKTS:PMCB) Continues to Erupt Higher
We will all need earplugs (or Beats headphones) to drown out the
banging on the PMCB door, for our platform technology, if/when we get breakthrough therapy status.
The possibilities are truly awesome!
GO $PMCB GO!
Hey Pete, the 505(b)(2 approval route....
Provides that protection and up to 7 years exclusivity.
I posted about it further down the board.
GO $PMCB!
For those are saying "This is taking too long......."
Leonardo da Vinci created plans for helicopters and submarines
which have been utilized to destroy lives.
How long are you willing to wait for an innovation that can improve
and save lives?
I have posted again showing you how and why.
PMCB can collaborate with any existing FDA drug where targeted
application improves the efficacy of the drug, the dosage regimen
of the drug, and reduces the toxicity to the patient.
If the work that has been done behind the scenes is what I suspect,
then we all have a reason to be cheerful.
Go $PMCB!
Further information.....Federal Register.
Dosage form is the physical manifestation containing the active and inactive ingredients that delivers a dose of the drug product. This includes such factors as:
(1) The physical appearance of the drug product;
(2) The physical form of the drug product prior to dispensing to the patient;
(3) The way the product is administered; and
(4) The design features that affect frequency of dosing.
Drug product is a finished dosage form, e.g., tablet, capsule, or solution, that contains a drug substance, generally, but not necessarily, in association with one or more other ingredients.
Drug substance is an active ingredient that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the human body, but does not include intermediates used in the synthesis of such ingredient.
Efficacy supplement is a supplement to an approved NDA proposing to make one or more related changes from among the following changes to product labeling:
(1) Add or modify an indication or claim;
(2) Revise the dose or dose regimen;
(3) Provide for a new route of administration;
(4) Make a comparative efficacy claim naming another drug product;
(5) Significantly alter the intended patient population;
(6) Change the marketing status from prescription to over-the-counter use;
(7) Provide for, or provide evidence of effectiveness necessary for, the traditional approval of a product originally approved under subpart H of this part; or
(8) Incorporate other information based on at least one adequate and well-controlled clinical study.
The full ruling is here but is heavy reading.
Search within the document for the words efficacy and dosage.
Go $PMCB!!!
There is a reason I asked the question about 505(b)(2)
I read today about a micro-cap pharma getting a fast track using 505(b)(1),
though the name was not mentioned. Taking the 505(b)(2) Route is less expensive,#
can reference existing submission evidence
from the FDA-approved drug manufacturer. Sounds a lot like a "best
in class" drug that could get it's efficacy improved quick time....
The article said it was for existing drugs using an alternative
delivery method (targeted?)which increased the efficacy of said
drug and reduced the toxicity to the patient.
Sounded a lot to me like ciab. (see the link below.. I wonder if..)
Taking the 505(b)(2) Route
Go $PMCB!
Why are we not using the 505(b)(2) regulatory pathway? ?
It seems to me that this would be the best way to get our ciab into the health system. Anyone see or can tell me a reason why we have not tried either the 505(b)(1) or 505(b)(2) regulatory pathway (though the latter is less expensive).
See Below.....
Galena Biopharma Confirms Regulatory Pathway for GALE-401
This statement alone tells us we are on a winner!
"Dr. Manuel Hidalgo: “Through a series of clinical and preclinical studies led by Dr. Von Hoff, myself and many other excellent investigators, we showed that Abraxane® is effective in pancreatic cancer leading to its approval. The development of this drug provided us with a firsthand experience on how to take a new agent from concept to approval. We will now apply all of this knowledge and expertise to develop Cell in a Box® for pancreas cancer treatment. These are obviously very different technologies, but the principles of conducting a high quality step-wise development plan are similar.”
It is not a matter of if, as it is with most small caps, but when!
There is no try....only do or do not.
No try or not in the above quote.
Go $PMCB!
This statement alone tells us we are on a winner!
"Dr. Manuel Hidalgo: “Through a series of clinical and preclinical studies led by Dr. Von Hoff, myself and many other excellent investigators, we showed that Abraxane® is effective in pancreatic cancer leading to its approval. The development of this drug provided us with a firsthand experience on how to take a new agent from concept to approval. We will now apply all of this knowledge and expertise to develop Cell in a Box® for pancreas cancer treatment. These are obviously very different technologies, but the principles of conducting a high quality step-wise development plan are similar.”
It is not a matter of if, as it is with most small caps, but when!
Go $PMCB!
Even the Link to the 100K....
....after hours sale no longer works and says PMCB unknown symbol.
Very strange.................
Fix Tricks?????
3 days ago I was able to check the Nasdaq for after hours
purchases, which I posted here.
This morning (I'm in the UK btw) it was all working good.
When the US pre-market kicked off the PMCB symbol was still
recognized but in about half an hour I started to get
"Symbol PMCB not recognized"
I have been unable to access PMCB after hours data since,
when I could before.
Any ideas?
ps. Thanks for the warm welcome :)
First Post.
Rogue trader here (<<newbie)
Greetings to all on this PMCB tip.
After hours shows this.....
After Hours Time (ET) After Hours Price After Hours Share Volume
16:13:25 $ .1215 High 100,000
Read more: http://www.nasdaq.com/symbol/pmcb/after-hours#ixzz4VOqQ1Oud
I have this (no advice, just a hunch)and I will be holding until God comes or PMCB goes Nasdaq proper.
Just like IBM became the platform for the majority of the worlds
computer programs to execute on, I believe that PMCB ciab will
become the delivery mechanism of choice for all effective new (and some older) drugs. Therefore I will be increasing my position exponentially until take off.
Go PMCB!!!