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I never quite knew just how the super computer, Big Ben, aided in the development of Brilacidin until just recently.
Brilacidin was based on a natural anti-microbial peptide, magainins, found in African clawed toads that had shown an eerie ability to withstand bacteria and viruses. The problem was that the core of this natural peptide was not strong and led to many negative side effects.
The super computer was able to formulate a very strong core for the synthetic peptide mimic (Brilacidin) and reduce the negative side effects of it at the same time. Took a long time and lots of cash but in the long run seems to have been well worth it.
This description is in very simple layman terms of the procedure but that is what I got out of it. Hope you get the point.
Being that the patients in Compassionate Use were so severely impaired compared to those in the trial and the restrictions placed on them were so less (they could have secondary issues that could/would prevent B from working and thus would have been not able to become a trial patient) that important data was probably achieved even if the patient didn't survive.
If they were able to be dosed longer, if they were able to eliminate the viral load even for those on respirators, if they happened to help some secondary condition beyond removing the viral load, etc. Lots of areas that important data could be harvested rather than just the patient died or survived as most were in very, very bad states of health. Remember, Compassionate Use was the last ditch effort and by then many, if not most, were already too far gone for survival. But somewhere I had heard that they did have some successes that were quite impressive.
Nothing hard and fast, but rumors.
If survival rate of those on respirators was 5% and in Compassionate Use the survival rate went to 20%, I figure that would be a remarkable improvement for the circumstances.
The PR regarding Brilacidin Top Line Results is simply the BEGINNING of Brilacidin racing to commerciality and massive revenues, thus causing massive share price appreciation. All the hoopla over the recent rise from the low .20s to the now high .40s is a minor blip, a bit of icing on the cake that overall is next to meaningless.
Regardless of what happens the rest of this week and next week prior to the PR release in regards to the share price, the rise really doesn't start to take off until after TL Results. Why?
Without excellent TL results, the last week or so price rise is just smoke and mirrors - meaningless. So why are solid longs so confident as to the TL results? We know how B was developed, the science behind it, the history it has of being able to transfer in vitro results from labs into in vivo results in human trials, the happenings already in the trial that showed safety is rock solid and a non-issue, and the knowledge that B has never failed in being able to kill any bacteria or virus to date that it has encountered. The science says it will kill CV19 and it will kill it ALWAYS, so the efficacy in the trial is pretty much a given. The rumors of excellent Compassionate Use results give tremendously enhanced expectations that the efficacy from the trial will be overwhelmingly positive.
What can we expect AFTER TL results to not only keep the share price from sinking back into the .20s and .30s as it has done every time to date so far? We will have the entire world of medicine, media, governmental agencies, and foreign countries aware that B is the gold standard Covid therapeutic. It cannot be hidden, it will not be left stranded as other POS Covid drugs are pushed ahead of it, and it will be highly investigated for the broad spectrum of uses it has shown possibly/probably being able to control in prior in vitro testing.
Here are major factors regarding PRs or media blitzes that should occur after positive TL results:
1.Media muzzle will be removed so that Brilacidin becomes a very hot topic worldwide. Mass populations will realize death is all but removed from the Covid equation as long as patients get treated prior to damaging lung stem cells. This should open up all economies of the world and bring life a bit back to normal.
2. Compassionate Use PR should follow pretty rapidly and many are saying this data could dwarf the trial results as these patients were many times more seriously at risk than trial patients and in a body where recovery was about 5% Brilacidin was found to almost totally bring about complete recovery in all patients.
3. The #2 data should provide for extremely fast EUA OK by the FDA for B and this would allow/bring about WORLDWIDE requests for B for very needy patients (read that massive revenue stream coming to IPIX).
4. Should bring about some grants being given to IPIX/Brilacidin. This would effectively put a halt or a severe blockage for any further dilution of shares.
5. Possible partnership for the coronavirus sector of the Brilacidin platform and this would GREATLY enhance IPIX in the eyes of the financial world. Should this come about and the naked short situation is as large as some seem to think it is w/ IPIX, this would crush the naked shorters. We could see some sort of action like was seen w/ GameStop and AMC. This is a WAG but possible.
6. Government RBLs (regional bio labs) are about to publish two more peer review articles regarding Brilacidin findings (one may be the finding that besides working on enveloped viruses only it actually works against non-enveloped viruses as well (to viroligists this is a big deal!!)
7. Expect DOD to become a MAJOR facilitator of B as a first line defense against bacterial and viral weapons our troops may encounter in the field. They just recently authorized research into over 20 of the world's worst viruses to include Ebola and Marbug viruses. Brilacidin will be the FOCAL POINT of virologists worldwide!!
8. Major people very familiar with the B story will be able to push Brilacidin in TV, radio, Congress, etc. Brilacidin will become or possibly could become the penicillin of the 21st century due to its extremely broad spectrum of uses and rock solid safety profile.
BOTTOM LINE: Top Line Results are not the finish line, it is simply the starting gate being thrown open for Brilacidin. ALL INVESTORS have to quit looking at this stock as a penny flip play, this is a new arm of medicine, a foundation for IPIX to become a possible BP in its own right, and a generational wealth facilitator for many long term holders who have significant positions. Even 50K shares could rocket somebody to millionaire status in a few years IMO.
If history holds true to form, I wouldn't be surprised to see price spike nicely tomorrow morning and then get crushed in the afternoon. Volume is still pretty paltry and with no news to date I am not believing this is all due to new, aggressive retail investors.
Would be just like MMs to try and make all new investors wonder if this is really a strong play (as us longs know it to be) or if it is just another penny stock that should be held only for penny gains and then sold.
I hope we are close enough to top line results to make most new investors secure enough to hold until they are released and make their decision then to hold or sell. That would really give the MMs something to think about.
I am hoping for the best, but wanting those that are new here to realize should a big dip occur it is all scripted by those still controlling the share price and that control will ONLY be broken by great results, some news of incoming grants, and possibly a partnership for some part of the Brilacidin platform.
This is the real deal, but it won't be a straight shot up as to share price. Lots of dips and spikes. Play for pennies or stay for massive long term returns (share price should continue to rise significantly IMO for the foreseeable future and a buyout within 3 years in my opinion).
Do your DD on the science. That is the key to this investment as you will realize you have stumbled onto a new arm of medicine with potential that is beyond belief.
JFM talked about Dr. DeGrado and I am over the top pleased that he should make quite a large sum of money for his role in developing Brilacidin due to his employment at IPIX and the many shares he has likely been given for such work. He will have earned every penny and even that will be far, far, far below what he really should have been paid for creating this wonderful product for the world.
But he wasn't the only creator on the Polymedix team. He had a handful of collaborators and I hope all of them have been able to accumulate a strong position in IPIX so they will also benefit from IPIX taking it out of the trash heap and bringing it to near term commercialization. They all deserve to be millionaires for their roles in Brilacidin.
I have total confidence in the upcoming TL results so my thinking is now more on production of B-CV and getting it to patients worldwide as quickly as possible.
I hope that the main producer of Brilacidin is still Evonik, a company we signed an agreement with in Apr 2018 for bulk production of commercial grade Brilacidin. Evonik is a German company with approximately 38K employees and production facilities on a global basis to include all continents except Antarctica. https://www.ipharminc.com/press-release/2018/4/23/innovation-pharmaceuticals-signs-drug-supply-contract-with-evonik-to-bulk-produce-commercial-grade-brilacidin
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IPIX announced Jan 2 2019 that they had received additional patents for Brilacidin formulations containing water. After the link is a copied portion of the PR to show the wide-ranging uses planned for Brilacidin. https://www.ipharminc.com/press-release/2019/1/2/innovation-pharmaceuticals-receives-new-brilacidin-patent-further-expanding-intellectual-property-estate
"The “Issue Notification” of the patent (Projected U.S. Patent Number 10166232) covers Brilacidin in the form of a pharmaceutical composition containing water. The pharmaceutical composition can also contain Tris-buffered saline. The patent covers Brilacidin in combination with additional medicaments, such as: an antibiotic, an anti-inflammatory agent, an anesthetic agent, an anti-allergic agent, an acetylcholine blocking agent, an adrenergic agonist, a beta-adrenergic blocking agent, an anti-glaucoma agent and an anti-hypertensive agent."
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IPIX further announced in a PR dtd Apr9 2019 yield and purity enhancements in production to achieve drug supply optimization of Brilacidin. https://www.ipharminc.com/press-release/2019/4/9/innovation-pharmaceuticals-reports-enhancements-in-manufacture-of-brilacidin-phase-3-drug-supply
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The links can all be found on the IPIX website under Newsroom/Press Releases and are on pages 6,5, and 4 respectively from oldest to newest should anyone want to read the entire PR.
I am hoping Evonik is our current supplier as they have the capability to have made these enhancements (the timeline certainly fits them being the ones that upgraded the manufacturing process) and the worldwide production equipment to provide massive quantities of consistent quality worldwide.
It would also put IPIX in a much, much stronger position IMO when dealing with a BP (regarding a partnership) as IPIX will be providing all the development of Brilacidin to the point of passing FDA trials (at least thru Phase 2) and being able to provide the product itself to the BP. The BP then only handles marketing and distribution and IMO IPIX should be getting possibly the lion's share of the revenues, but that is just my take. Certainly should put us in a different position of strength than BP has ever encountered before.
I had heard the manufacturing process held no exotic components, but I had heard it was a very delicate process and mgt had put in a lot of money to get the process maximized for efficiency and purity.
Seems like IPIX was doing a lot behind the scenes over the last couple of years and this should greatly reward shareholders going forward.
At the least, no BP can BS us as to cost of manufacture, time of manufacture, or consistency of quality that can be achieved. Have to admit I don't look kindly on BP to treat their minority partners that fairly.
Looking at the laws for MMs, it is obvious the laws were a payola payback from Congress to major Wall St players. Money well spent by these hedge funds and major financial institutions and a major kick in the crotch for all retail investors and pension fund managers.
American corruption at its finest. SEC and FINRA rank right up there at the very top of the list. FDA not far behind, but then most every Cabinet has its own list of preferential treatment laws. Otherwise, how could all Congress members become millionaires?
The action shows that those trying to suppress the share price are working overtime, using every play in the book, and are still not succeeding.
I have attached below the trading data for IPIX over the month of October. Please note that the first number given is the total daily volume, the next number is the daily shorted volume, and the third number (percentage) is the percentage of daily short volume to total volume. Anything near 40% or more catches the eyes of FINRA. It shows dramatically that MMs have been trying to keep the price under .30 and have been only able to do it with massive amounts of short selling as most days are 50%+. They are sinking fast and the last 4 end of day painted trades at 3:59:59 attest to that. It confirms what I have been saying in that they keep digging their hole deeper and deeper. So though share price hasn't been rising that fast, the BUYING SIDE has been huge and those trying to keep it down are paying a hefty price to just try and hold it back. Excellent sign for the future. Wait until the volume is many tens of millions / day. Can anyone spell "Toast"???
Oct 27 NA NA NA 666,995 444,495 66.64% **
Oct 26 NA NA NA 728,535 494,653 67.90% **
Oct 25 NA NA NA 2,184,930 1,327,875 60.77% **
Oct 22 NA NA NA 820,075 482,734 58.86% *
Oct 21 NA NA NA 267,549 145,587 54.42% *
Oct 20 NA NA NA 678,632 362,936 53.48% *
Oct 19 NA NA NA 445,416 313,754 70.44% ***
Oct 18 NA NA NA 1,033,338 678,775 65.69% **
Oct 15 NA NA NA 2,115,766 1,500,362 70.91% ***
Oct 14 NA NA NA 371,454 197,327 53.12% *
Oct 13 NA NA NA 373,098 220,809 59.18% *
Oct 12 NA NA NA 337,975 125,841 37.23%
Oct 11 NA NA NA 654,529 302,770 46.26%
Oct 08 NA NA NA 655,172 468,537 71.51% ***
Oct 07 NA NA NA 358,465 160,933 44.90%
Oct 06 NA NA NA 286,542 156,179 54.50% *
Oct 05 NA NA NA 651,816 147,216 22.59% --
Oct 04 NA NA NA 1,868,526 495,794 26.53% --
Oct 01 NA NA NA 3,185,969 1,876,954 58.91% *
Went on a public site yesterday after a search to see when IPIX first mentioned B could be a candidate for killing filoviruses (Marbug and Ebola) and it was in their 11 Jun 2020 PR.
So I checked on the peer review article that was published and to date it has been viewed over 10,500 times. Now one or two investors may have looked at it but the vast, vast majority of views IMO were by virologists. Thus, IMO one cannot say Brilacidin is not known quite well by the elite virus researchers worldwide. Also means no chance of burying Brilacidin should anyone desire to do so.
I wonder now which RBLs are licensed to handle filovirus testing as I thought GMU was one level shy of being able to handle this virus?
You think a hush job wouldn't have tanked the share price????
I applaud him for getting this info out this early in the week. Shows strength rather than trying to bury it after close on Fri.
My comment reflects my OPINION that there is a massive, and I mean massive, naked short position against IPIX. I will not go into numbers so no questions regarding same please. Can I prove it, no, but I have a person in my circle of data sharers who is about the smartest person I have ever seen in analyzing daily trading action and has consistently followed IPIX since the MAKO take down and can give point by point examples showing it is a classic short play. This has been going on for years so the position has steadily grown during the long periods of price compression. They almost had us beat but Covid allowed a "rabbit hole" IMO for IPIX to survive and now the ones with the boot on their throats are the naked shorters.
Certified correct, no. But IMO quite similar to expected trial results - not guaranteed but based on prior knowledge of how Brilacidin came into being, the super computer analyzing to maximize benefits and minimize side effects, the SI, the RBL investigations, the planned peer papers, the DOD Biological Weapons convention presentation, the safety validation DURING the current trial by the Oversight Committee, the fast tracking of B, etc, etc. one can make a pretty good case as to the expected outcome.
As I have consistently stated, I am a fringe player that happens to have acquired a circle of excellent friends and qualified people in various fashions that I trust as they spell out their reasoning, not just making outlandish statements. That is the basis for my comment.
Excellent top line results will put an end to their belief that they can bankrupt IPIX. A major grant or a major partnership spells major financial despair for many of them an should the government jump on the Brilacidin bandwagon I believe we could see some astounding financial tremors akin to the GameStop and AMC fiascos.
If trial doesn't show B is a "killer" for Covid virus to the max degree, then IMO they may as well close up the RBLs for not being worth a damn with all their in vitro testing.
Same with their science measurements, a drug cannot attain a 426SI and not be effective when in prior trials it showed excellent effectiveness (though these trials were more for bacteria, not viruses).
The only surprise I can envision from the trial is if somehow the SOCs show more effectiveness than they have displayed in all prior tests and in actual use on patients (which is next to 0). If that is the case, I wouldn't classify the results as a surprise but as a "rigged" result (no, I am not talking elections here).
I go back to my same mantra "Science is science and will work every time the same way". Brilacidin will be the drug we know it to be and the results will reflect the same.
Cannot believe MMs are still digging their hole deeper. Someone going to have a very bad week in that camp next week. (CDEL CEO - Just who in our company recommended the position we are currently in????)whoever it is, I would think about making my exit as quickly and quietly as possible so they could never find me.
Look at the daily volume - Next to nothing. All that was done today were just MM games and strategies. Will continue until top line results come out. That will we the only factor that will make IPIX succeed or not.
When volume gets over 10MM per day, then it may be time to worry about such things as you brought up today. But when less than 700K, no worries.
I don't believe B was ever expected to replace the vaccines. They do their job, however effectively or safely, and that market will be left to them.
But for those far fewer people that need something to stop Covid once it hits them and symptoms go anywhere beyond extremely mild that is when Brilacidin steps in to make sure the lungs and other major organs don't get damaged to a degree that the patient dies or has life changing damage to the organs.
Vaccines to date haven't yet been able to open up all the states to normal business and life (such as schools, churches, entertainment, restaurants, etc) and maybe Brilacidin, by stopping the threat of death, will go much further in allowing the above to return to a state of normalcy.
Market for each. Bottom line is a safer world from Covid.
And this is just ones aspect of a broad range of positive changes Brilacidin can bring to the world and medicine in particular.
As to the trial, we know it is safe from what has occurred in the trial to date as to positive decisions from the FDA. As to efficacy, why does anyone believe Brilacidin won't be able to kill the virus in the body when it has proven in other trials it effectively does this? A leopard can't change its spots, Brilacidin can't work/not work in the human body. It is going to work in ALL cases. IMO
Amazing what tens of thousands of hours on a super computer can do to perfecting a formulation for a new drug. Confidence to the max is the end result. IMO
From what I have come to believe from various sources CU with Brilacidin has been ongoing with more patients in the Florida area. That to me shows they must have seen some very positive results and that some doctors must be spreading the news as to Brilacidin for moderate to severe cases.
I cannot give any verified references to prove I have assumed correctly but that is what is my opinion as to what is happening.
As you put in bold per my post, I always make it known I am only giving my estimation of the situation.
I may not always be correct, but I always shoot straight as to my opinion.
As an aside, I take the very long time to verify data as extremely positive. IMO they are getting such good results that they are going over them with a fine-toothed comb to make sure they didn't make any mistakes.
We don't have long to see how it all plays out.
If the Compassionate Use results are stunningly good as I have been led to believe they will be, one would expect that soon after the PR announcing same that there will be a massive run on Brilacidin in inventory.
One can only hope that somehow there has been some inventory coming into being to take care of the demand.
Otherwise, would it be more merciful to hold off on the PR until some suitable inventory is acquired so that those currently fighting for their lives won't have false hope thrown at them when told the remedy for their plight will not be available for many weeks or a few months?
It most likely would have got rid of the Covid virus and that couldhave been the difference between living and dying. I realize not a great chance, but better than nothing.
But after all his other ailments, he most likely said to forego any other treatments as he was ready to die.
Sad for such a sad ending to a good man.
Did you find it odd that with the DOD doing investigational work on Brilacidin at 3 RBLs over the last year and a half, the results ending with all 3 preparing to publish peer reviews,Brilacidin being a topic at the DOD BioDefense Convention (which was cancelled due to Covid) in Orlando in August, and the FDA allowing Compassionate Use of B for patients in need that Gen. Powell was not given B at Walter Reed, the HQ of Military Medicine? Could one possibly believe that Walter Reed did not know of Brilacidin?
I was stunned. I would assume his family will be in turmoil when they find out he may have been saved with something that was available when he was in dire straits.
You may be right, but by the end of the year .....????
Things could go just as you say, but they could also explode. I know that we are in for a sustained rise that will be staggering by the middle of next year IMO.
I am pretty sure there will be some that will realize the value in IPIX in a very short time. If it is Baker Brothers, great, but if not doesn't really mean a damn as there will be others where IPIX/Brilacidin fits better into their investment strategies.
But thanks for making that point for all new investors ....
THIS IS AN INVESTMENT, not a day trading play for pennies. Know what your own, do your DD on IPIX, and it will be the most financially rewarding amount of time you will ever have spent.
-Let's say Brilacidin can open up states such as CA,MI,NY,etc? What should that be worth? What is it worth to get people out of emergency rooms due to CV quickly for hospitals/insurance companies bottom lines? What is it worth to medical doctors/nurses to finally have their lives given back to them? What is it worth to everyone to know that CV is no longer a death sentence even if symptoms go beyond the very initial stages?
To me, worth a lot more than $.70 (maybe not in a few days, but in a very, very, very short time)
I also know that if I was a short right now I would be feeling the same way a wolf that is caught in a trap and knows that to get out he must gnaw off his own foot must feel.
Couple of crazy questions that came to mind:
Could Leo sell just the "small molecule" platform limited to all medical issues for use in the human body and keep the "polymer" platform to be able to franchise that out to various companies? Could easily make distinct areas that each franchisee would be limited to which isn't possible with the small molecule since B going thru the blood is going to work on problems wherever it finds them and that could cause massive legal problems between the various franchisees for specific conditions in the body. Also the reason I believe the "medical" B platform must be given to one BP.
I would like to see Leo sell the rights to the 'small molecule' platform of B and the Kevetrin rights to a BP (doesn't necessarily need to be the same BP). I would also like to see him sell the 'polymer' rights to a major multi-national industrial company that would jump all over the various industrial product possibilities quickly. A BP might just let them languish.
Guess the Proctosigmoiditis royalties from Alpha Sigma would also go to the acquiring company - AS could prove to be a real pain in the keister down the line for IPIX in selling the platform or the whole company if they say they will match any offer since I think they have first right of refusal (or right to match highest bid) for the whole IBD platform. Anyway, guess the acquiring company inherits the royalties of the part of the IBD platform already owned by AS and any further parts of the IBD platform they desire to purchase? I personally don't think AS has the funding to buy the entire IBD franchise but I could easily be wrong. If I was the acquiring BP wanting the entire B platform, I could easily form a subsidiary that could make an outrageous offer for the balance of the IBD platform that AS couldn't possibly match and since the subsidiary monies ultimately come back to me, it cost me nothing to keep all the rights. Hope I made myself clear as it reads a bit sketchy to me.
Great week looking us in the face!!!!!
Some may say that your estimate for a deal sounds way too lucrative for IPIX based on past deals for bio startups but I fall in line more with you for the following reasons:
1. BP will have bypassed ALL RISK for the drug in both its safety profile and its efficacy shown by all trials to date.
2. BP has RBL investigational support that B should be able to handle not just Covid but ALL corona viruses to include Flu, HIV, Herpes, and more. These revenue streams are huge. It has also shown B should work not just on enveloped viruses but also non-enveloped viruses. This includes those viruses normally affecting young children. Again, more large revenue streams.
3. RBL testing has also shown that B should be a leading candidate to the DOD as a primary defense against all biological and viral attacks on American forces. This is supported in that to date B has not seen a bacteria or virus it cannot kill. 3 RBLs have been testing B now for over a year and the success is shown in that B was to be a topic presented at the major DOD Biological Defense meeting in Orlando in June that had to be cancelled due to Covid. It should be noted that all 3 RBLs plan on issuing peer review papers on their findings - major success right there.
4. Being anti-inflammatory, major lung related revenue streams become a strong possibility (COPD, Asthma, Bronchitis) and also for MANY more issues such as encephalitis.
5. B has shown a propensity to cure most all ailments in the GI tract and this will confirmed soon when the UC trial results are achieved. Again, very large revenue streams being attacked by B.
6. B has been said to have many more areas it should be able to target that have as yet to be found but are strong areas for positive expectations (Example: "leaky gut is expected to be handled by B and leaky gut has now been linked to 'leaky brain' which should also be a promising target and in here we are talking about Parkinson's Disease, Lou Gehrig's Disease (ALS), Alzheimer's, and dementia). Another major area are all auto-immune problems, kidney, and liver problems.
7. To date B has shown an excellent ability to transfer in vitro results into in vivo results so all the above areas mentioned above are not just pipe dreams but very realistic areas that B should prove a leading factor in solving for medicine.
8. The above are just for the revenues based on the "small molecule" targets for Brilacidin. The "polymer" revenue possibilities (polymer being many small molecules linked together to form strings of B) in industrial products to include paints, textiles, plastics, etc. is astounding and I wouldn't even hazard a guess as to where these numbers could lead but it is large.
Now add all the above revenue streams and you are talking hundreds of billions a year. So if the total is $200B/yr and B only gets 5% of the market (which IMO is ridiculously low) that is $10B/yr and the upside could be $50B+/yr.
Remember, we are not talking just a drug but a new arm of medicine and that is what separates the abilities of B to all other drugs.
The numbers above are simply for B. I have not even addressed the potential of Kevetrin and it could be a monster stand alone and/or complementary drug for cancer treatments. It has revenue potential way, way up in the tens of billions, or more.
So add up the possibilities, the lack of risk, the already successful findings for Covid (once successful top line results are released this week or next), and the safety of the drug and what you project is a seemingly paltry amount IMO.
I feel whoever gets the Brilacidin platform is not just buying a drug but is attaining the library of a big pharma in the multitude of major revenue streams it will be able to target.
The problem with "net" profit royalties is like "net" profits from Hollywood movies - I don't know if any movie EVER has posted a "net profit" to date. Accounting games at the highest levels.
I think the actor James Garner got royally screwed in a deal like this.
The producing company of the Brilacidin wouldn't have a QMS at the manufacturing site that would meet the requirements?
In other areas of business, the manufacturer of the product has the responsibility of being fully certified that they can produce to specifications of the industry or government requirements.
Think this is a "non-problem".
I highly doubt IPIX had any form of testing done by themselves as to the B used in the human trial.
If another level of testing to back up the mfr's testing is needed IPIX could always hire a testing facility to run spot checks on the B.
To tell the truth I am pissed off somewhat at first glance. I thought the salaries for Leo (and especially for the BOD which IMO have had NOTHING to do over the years) were acceptable and success is part of normal expectations, not something that sends mgt payola thru the roof.
I didn't see any of them give back part of their monies when Prurisol failed.
But as in most cases I shoot off my mouth prior to getting all facts so that is why I am only somewhat POd. I am sure some people I trust will fill me in on the logic and necessity for these actions.
The fact that Brilacidin is helping Covid patients in severe straits via Compassionate Use is fabulous, but another wonderful result from these applications of Brilacidin is that there should be data being collected that may show improvement in many major organs as well due to B being applied. This should/could include the lungs, kidneys, liver, possibly the GI tract, and other areas that could bring about other great avenues of revenue.
These patients could have some "leaky brain" issues such as ALS or Parkinson's since they weren't part of the trial where such patients I believe were excluded and any improvement in these conditions would be near miraculous.
I am just stating possibilities above as Brilacidin continues to surprise us all with its ever-widening scope of possible uses.
It is not often that a new drug only continues to surprise to the positive side but then how many new drugs are a new arm of medicine such as is Brilacidin?
The delay that was so frustrating a couple of weeks ago is now easily tolerable as it seems there can be no other interpretation of recent events other than we will get excellent top line results.
Anybody else find the recent daily volumes being so paltry a major indication of the "games" being done over the last few years as to IPIX share price? I feel the recent daily volumes are more in line with actual daily trades being done minus those simply being bogus for "volume" resetting.
Attached is a link defining "payment for order flow" and how it may be affecting IPIX.
https://www.investopedia.com/terms/p/paymentoforderflow.asp
Who says Leo isn't doing things to crush those that have been trying to destroy IPIX for years?
Haste is not a great attribute when compiling a compelling case that could be worth tons of money. This is all simply my opinion but I do know that if Leo has the chance he will destroy the clowns that have been haunting IPIX.
My idea of punishment - DECADES of jail time (all to be served,not house arrest) for all top management of these hedge funds and cabals. Money is not the issue as they have near unlimited funds - either eliminate top management thru execution or jail time.
I see no chance in hell that the govt takes any action on shorting rules for MMs. They are all in it together at the expense of the general public.
They will talk a good game until the general backlash seen by AMC and Gamestop dies down and then all action will slip into oblivion.
I still haven't seen any reason a MM has to ever cover their naked shorts since they just keep shifting them between themselves to evade supposed SEC or FINRA oversight.
The only thing possible is MASSIVE trading days for weeks on end so that it becomes shown there are not enough real shares to trade to cover all the daily trades. Hope we get to that point one day.
If this post is rated off-topic, then all is just games as naked shorting has/is/and will continue to be a major feature of this investment.
No, military would be an additional sector with excellent knowledge about Brilacidin.
I was mainly referring to those in Congress and major government agencies.
I think there are people in powerful positions that will not let Brilacidin go unnoticed. Medical, governmental, and media people involved.
There SHOULD be hell to pay, but in today's world of corruption I doubt if anything negative happens to those that repressed many fine medical products over the years from coming to commerciality.
Article IMO has no bearing to Brilacidin as what negative properties can anyone intent on hindering the distribution/commerciality of B use as to negative side effects?
Molin.... caused defects in babies and other MAJOR problems. Without a doubt a drug that should NEVER have been authorized for use. Puts up a MAJOR red flag for Merck in future dealings w/ FDA as I see it since a total sham of a "cure" or "treatment".
Ivermectin - this one is iffy IMO as some say it is wonderful and others not so. Not educated enough about it to make a declaration but the naysayers seem to have found something to make the FDA/CDC not allow it to be used.
Brilacidin - Tingly fingers and toes is about all I have read as to side effects at the dosage needed to combat Covid and for all other uses of it. Why would the FDA have done 3 tests on the safety prior to and during the current human trial, resulting in their OK to use it for Compassionate Use, if it didn't show itself very safe?
Being conservative is one thing, but the safety side of the FDA equation IMO is a no-brainer thumbs up for Brilacidin and those trying to slander/libel it will have some explaining to do as to what they perceive its harmful side effects are and how they came to such a conclusion.
Major issues between posters as to valuation regarding Brilacidin platform. Would be interesting to hear from many posters their ideas to this matter, if only a brief one sentence as to a number placed on the value.
Here is mine: $15B+
Why?
There has never been another drug to date with the wide spectrum of uses, excellent safety profile, and 3 methods of action as does Brilacidin.
There has never been an antiviral, bacterial, fungal, inflammatory, etc drug to date as is Brilacidin.
There has never been another drug to date that addresses problems in a number of different medical areas that are each in the billions of dollars (many, many billions for some areas) as does Brilacidin.
The above sounds good but what sounds even better is that to date Brilacidin has performed in all testing and trials exactly as Dr. D said it would and these tests have proven to transfer to human trials extremely closely to what had been found in the lab.
Brilacidin is truly a new arm of medicine.
This could be as big a difference as what Tesla brought to the table way back in the beginning days of electricity. People were hung up with Edison's near useless DC current while Tesla's AC power is still in use today and is as applicable as ever.
I see Brilacidin in the same light for medicine and thus it should be valued as such.
I only worry about what is happening now, not what could have been or should have been.
I am very happy where IPIX sits today with the potential we have going forward.
You’ve basically bought into the BP scheme of keeping the SP low so value of company must be low. I am at complete odds with your thinking.
Revenue potential be damned, only look at the current financials. Ridiculous IMO
Do you believe reformulation is possible to make B oral?
TIA
I totally agree with what you wrote in that if a BP had offered Leo a proper offer years ago that had a significant increase in royatly percentage as B and K each earned commerciality and grew revenues, thus earning both sides a lot of money and equal risk, that Leo would and should have taken it.
But I believe no BP came forward because the play book always has been the startup bio only gets mere pennies on the dollar at best.
Offers were so meager or lacking that Leo could not take any in good faith to shareholders. Thus we are now at where we are at.
Am I disappointed in the resulting dilution over the years, yes, but they were necessary IMO and Leo did well to keep them below 500MM. What really galled me in your post was saying Leo has been playing the company for his salary and willing to sell out us stockholders for his personal gain. That is the crock of which I spoke.
Now we find ourselves in a position where IPIX has taken ALL THE RISKS and brought Brilacidin to the brink of MASSIVE revenues in the next few years. Thus, I feel IPIX should receive the lion's share of the revenues, not the scraps.
I want Leo to make them pay thru the nose. They were too stupid to realize the value of B, too bad for them, now they pay handsomely to have any part of the platform.
What a crock of crap
How much could it have cost Merck to put out a POS?
And yet some learned clowns were at first praising its properties.
Revolutionary products can do things regular products can't, such as the electric car.
Brilacidin will do the same for medicine IMO