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That is about $100 share price for IPIX. Come on Brilacidin!!
Read May 4th PR. ADDITIONAL STUDIES.....this is the additional studies. We will get human lung data soon
This is same lab data from PR on the 4th? We still will get newer lab data on human lungs soon too.
Right?
Children illness hitting the media across the nation. Some sort of INFLAMMATORY illness associated with children who were diagnosed with COVID at some point. Very strange and also scary if you have kids.
Brilacidin's anti-inflammatory property may be able to help. please.
https://www.nbcchicago.com/news/coronavirus/doctors-warn-of-mystery-illness-afflicting-children-who-previously-had-coronavirus/2267897/
IMO- as you heard....there has never in history been an approved RNA vaccine. The preclinical always looks great but never translates to humans. So....I hope there is a solid vaccine obviously. But.....following history......this is an uphill battle.
Brilacidin as a treatment to save lives and then allow human natural anti body’s to be made is basically the same thing. Less death...treat the disease and allow body to build immunities.
Like! Great Opinion Farrell90!
The facts lead to greatness
Great news. Drug is already delivered too. Test gov! Let the drug do the talking. IMO.
Next week Brilacidin starts testing on human lung tissue. I truly believe and hope the trio effect is proven. This is exciting. Leo please be humble and rub elbows with others that can help. Do not be arrogant
It’s all true. I can’t believe that a pandemic has to happen and did happen to restart this company. The drugs are truly phenomenal and this event could be the chain reaction to get things rolling again.
Let’s pray for a great trial week next week!
Thank. Also saw it on CNBC.
If we go by history: Brilacidin began testing WEEK of March 16th. Results were PRd on April 1st.
So I’d assume Mid May. IMO.
Through his attorneys, Bright said he wants the inspector general to "investigate the manner in which this Administration has politicized the work of BARDA and has pressured me and other conscientious scientists to fund companies with political connections as well as efforts that lack scientific merit."
Exactly why lil IPIX gets no love
I have zero doubt that B can have a positive effect on severe Covid 19 cases. Reading the news from China that they have confirmed over 30 strains I find it very hard to understand how a vaccine will be successful and in short order.
So my question to Leo and the scientists...what is the ideal delivery method for B? IV or inhalant!?
If B can stabilize the cytokine storm that kills patients, we have a home run. IMO.
Additional pre-clinical and clinical data support Brilacidin’s therapeutic potential to inhibit the production of IL-6, IL-1b, TNF-a and other pro-inflammatory cytokines and chemokines (e.g., MCP-1), identified as central drivers in the worsening prognoses of COVID-19 patients.
Great article: https://apple.news/Aci-DmtQVQsu3uWuq5Vz13w
Explains how our own bodies and our immune response are the wild card to this virus. The more and more I read about the science I am more hopeful Brilacidin is an answer.
Thanks TD. Our later days will be better than our former days. IMO.
It is also good PR and free testing on Corona Virus overall. It adds value as long as there is positive results. It appears positive so far.
I wonder if Leo has to order more B for the secondary lung trials?
Has anyone had a chance to read the scientific literature? Will do at lunch but curious
My neighbor works at a Hospital as a Resp Tech. She has worked 3 overtime’s in a row and has seen 12 people die. 3 of which were normal young adults. 30’s-40’s. No underlying conditions on several of those 12. This virus makes zero sense to doctors.
I can only pray for this world.
Remember when Brilacidin was going to be coated on medical devices and surfaces? That was so long ago.....might be a game changer again.
Save lives is what we want
I think 45 patients who are admitted in ICU on ventilators is the start. Let’s see if the govt and Leo agree.
Let’s hope Leo is presenting this data and plan. I hope we just move forward with more testing. It’s free and adds value in the long term. Most trials in this world have halted if not for Covid19, so it’s nice B can get some PR all while adding true data to the library. IMO.
Good info. Wonder if his trials will move forward at this point. Seems like all trials are being placed on hold across the world.
Great Dr!
Thanks Pete! Leo is going full steam ahead. I bet Dr Jorgensen returns soon.
Phase 3 coming in humans. 45 patients. The USA is getting destroyed and there is nothing to lose
IPIX Receives Data for Direct Inhibition of SARS-CoV-2, the Novel Coronavirus Responsible for COVID-19 WAKEFIELD, MA – April 1, 2020 (GLOBE NEWSWIRE) Innovation Pharmaceuticals (OTCQB:IPIX) (“the Company”), a clinical stage biopharmaceutical company, announced today it has received data supporting Brilacidin’s direct inhibition of SARS-CoV-2, the novel coronavirus responsible for COVID-19. The testing of Brilacidin was conducted by researchers at one of the U.S. Regional Biocontainment Laboratories (RBLs). Few compounds have shown activity against SARS-CoV-2, as summarized in the article linked below. Andersen P, et al. “Discovery and Development of Safe-in-Man Broad-Spectrum Antiviral Agents.” Int J Infect Dis. 2020 Feb 17;93:268-276. doi: 10.1016/j.ijid.2020.02.018. https://www.sciencedirect.com/science/article/pii/S120197122030076X https://ars.els-cdn.com/content/image/1-s2.0-S120197122030076X-gr5.jpg VERO cells, a monkey kidney cell line commonly used to screen small molecule inhibitors of viruses, were used to test whether Brilacidin inhibits SARS-CoV-2. Cells were pretreated with Brilacidin at increasing concentrations (at 2 µM and at 10 µM) for two hours prior to the infection. Cells treated with the vehicle alone (Dimethyl sulfoxide or DMSO) were maintained alongside, as controls. At 16 hours post-infection (16hpi), researchers observed a dose-dependent reduction in the SARS-CoV-2 infectious viral titers from the Brilacidin treated cells as compared to the vehicle-alone control, as shown below. (The higher number of asterisks denote higher statistical significance compared to control.) RBL Figure 1 The Company is reviewing data received yesterday and anticipates more data will be forthcoming. Following discussions with researchers at the RBL, the Company will provide additional information and insight into possible joint research plans going forward. It is management’s understanding that few compounds advance to this next stage of SARS-CoV-2 research. In a broader context, demonstration of Brilacidin’s direct antiviral activity against the SARS-CoV-2 virus supports the drug’s unique 3-in-1 therapeutic potential—antiviral, anti-inflammatory, antimicrobial—to treat COVID-19 and its associated complications. Additional data, based on successfully completed Phase 2 clinical studies in other clinical indications, using various modes of administration, show Brilacidin’s ability to inhibit interleukin-6 (IL-6) and other pro-inflammatory cytokines and chemokines, identified as central drivers in the worsening prognoses of COVID-19 patients. Brilacidin’s robust antimicrobial properties might also help fight secondary bacterial infections, which can co-present in patients with COVID-19
Let’s move Trump! Antimicrobial - anti-inflammatory Antibiotic. No brainer! Make it into an inhaler and the world moves forward......back to work we go!
Excellent. Talks to happen this week for next steps?
Very small chance but as this is blowing up....there is a chance. There are about 54 drugs that have extensive clinical data and considered somewhat safe. These are at top of list and B is one. Hopefully we get news soon and some of these dier cases can try IV Brilacidin And in Faith for humans it works. You can’t deny a single dose had phenomenal effects vs dapto in Absssi. So cheers to faith
Dr Zeke Emanuel on MSNBC The Last Word w Lawrence ODonnell
He is from University of Penn and will be back for a full hour to discuss how to fight this on Monday. Someone get his attention to sponsor B.....where it was born!
Trumps touted drug can kill
https://apple.news/AOKRrysD5S9uMyEdMJt90ig
I watched a great interview last night with a world renowned DR regarding the facts on current treatments and pipeline for vaccine and medications. He is a leader in HIV and other viral vaccines and he said that this chloroquin debate is so far off and there is zero proof and is misleading. The quickest path is true of finding a drug and repurpose to fight Covid19 but very unlikely to really work. Newer and less tested drugs is where we will find a more effective drug but will take around 2 years to cross tape. Great interview.
I still think we hear about brilacidin in the days ahead.
Just takes one. The drug has been through a ton which could jump it ahead by light years
That is crazy. Wow.
If IPIX gains national attention because it punctures through the virus like a water balloon.....and Lester Holt talks about IPIX....this could see gains of many tens of dollars with this hysteria.
How about a 20/20 on IPIX shortly after sowing the corrupt path of an emerging public biotech - mako - lawsuits - etc....all resulting in the first line of defense for a pandemic! Air it Lester
Positive results will move this and since there is a decade of data on B already with several human trials on safety this could be a quick remedy for the infected. Not vaccine but as the science states.....bacteria is actually what is killing people.
Hoping B shows it’s muscle over the next few weeks
Great PRESS! Thanks