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70 cents would be a great new launching point.
Is it attainable as the OS continues on the increase? Anyone?
Really, ...just an opinion is all I'm asking for. & from one or several who are not prone to repeating same'ol-same'ol for sake of pumpy-dumpy board design.
I'd certainly enjoy watching DNA[g] put up a "W".
Look After Yourselves,
JBear
top o' the mourning to ya, ........
Just got another call from DNAP BOD.
They called to say GO FCK YOURSELF!!
["...to what do I owe this understated greeting?" I said.
"to your optimism...you dumbazz pennystroker," she said, sneering into the phone again....
~Really, why DOES...DNAP always have the in-house ladies do their communicating...hahahahah]
>> Just joshin'; surely I jest, kid, pull-your-leg, ...quip....
DNA[g] has NOT returned an email (DNAP did rarely with the canned reply) but an incoming phone call would be wholly inconceivable...and unsolicited in most every way; unless it was to offer up a few-hundred-thousand shares in gratuity for the countless hours I’ve spent entertaining select folks with verse-prose on these vile DNA[g]P boards [when you get right down to it.]
Perhaps I'm being short-sighted, as bagholders can be...after so many years of patience...on a pittance gone to nada.
But then, conceivably, I was being that B4
...when the profits were ripe.
After all, hints were written all over the bathroom stalls.
Fodder to the (meaninglessness of) Morosite design & this shadow BOD...in simplest terms.
Time alone will tell the whole story.
I wish Pacino were a DNA[g] bagholder too.
Don’t get me wrong,
...I hope the earnest here find what they are looking for. I hope the process is still fledgling in its signals of the BOD minutes to come, ...and the floodgates are anxious.
I hope an illusive process therein only thickens the tree-line wherein the forest thrives in relative silence, auguring the seeds of integrity; & not that the vital energies of integrity itself had never even seen the reckonings of birth upon one grassy Sarasota knoll.
70 cents would be a great new launching point. Is it attainable? Anyone?
Look After Yourselves,
JBear
Easy: You've got mail._eom
g'mourning,
Just got a call from DNAP BOD.
They called to say FCK YOU!!
["...to what do I owe this greeting?" I said.
"to your trust, you dumb fck," she sneered into the phone....
~Why does DNAP always have the in-house ladies do their communicating...hahahahah....]
>Just joshin'; surely I jest, kid, ...quip....
DNA[g] has never returned an email, ...an incoming phone call would be utterly inconceivable...and unsolicited in most every way [when you get right down to it.]
Perhaps I'm being short-sighted, as bagholders can be...after so many years of patience.
But then conceivably I was being that B4,
...when the profits were ripe. The hints were written all over the bathroom walls.
Fodder to the (meaninglessness of) Morosite design & this shadow BOD.
Time only will tell the whole story.
Don’t get me wrong, ...I hope the earnest here find what they are looking for.
I hope an illusive process therein only thickens the tree-line wherein the forest thrives in relative silence, auguring the seeds of integrity; & not that the vital energies of integrity itself had never even seen it’s birth upon one grassy Sarasota knoll.
Look After Yourselves,
JBear
what'z yer point froggy? hey, aren't you one of those lone gunmen I've read about? ;o)
yes, mikenickels, sometimes less IS more. Agreed, but...
there was once a precedence set that suggested a one page resume of the less-is-more variety was thee preferred and most appreciated-by-personnel-dept-heads, etc. style.
well, truth is I have proven time & again, when revamping resumes for others, that the high-quality-more-information-IS-more variety of two page resume wins over much more often than not in a scenario involving a short stack of select finalists.
so, although keep it simple stupid pleases many, ...epic has been known to move a lot.
opinions vary, certainly, ...and I am pleased to hear so many on IHUB are satisfied with the new site. after all, we all [or most] are watching for those little DNAG successes, yes?
…appreciate the reply.
CosmicLF [big D, & geob]:
User friendlier, more succinct; ...agreed.
I was able to skim the entire site in comparatively little time.
Like a report, hand written by Sergeant Joe Friday. Jus’the facts, madam.
The truly more conservative, less contemporary look of DNAG.
The dynamics of pragmatism. Sometimes called matter-of-factness.
Hey, ...if it pleases you, then good enough; ...you may be of the in majority.
seems like a good question;
but not worthy of a kind reply on this board.
it figures.
Please, ......does anybody else feel that the new site is a bit of a step-down...or minimization of it’s predecessor? Although the other site was not as up-to-moment as a shareholder (...and the world-at-large) would probably like to see, it had more gusto with a hint of colloquial pizzazz, ...a pulse. I mean, from oils on canvas to watercolor on construction paper. Is it an expense cut? Not to put-down watercolor, ...but the site feels more like a placard now, ...and it used to feel...well, ...dense and...established. I, personally, was hoping to see an updated site, yes. But certainly thinking much more “update” than...revamp & pull-back. It’s as though we’ve gotten another big door closed on us, the community; ...or something to that extent. Not trying to be negative...in the candy store, ...just airing a consideration.
In short: The previous site seemed MORE dynamic, ...No? Whereas this one appears stripped-down upon first glance...and with a further look inside. Another pragmatic visual personality change from a T.F. to an R.G. outlook?
Help...me...see...the change-for-the-better; ...all I’m asking.
Anybody care to show me the light here?
Really, ...it’s an earnest question.
Chrisbaskett:
imo: ... .... ...& yet he appears to be able to engage/distract much of your conversational space. Drawing on a measurable amount of yours and others intellectual free-thinking. THAT, alone, IS something, ain't it? Maybe it's everything; ...or, at least, too much. To this day, I still am NOT moved by the fakery of such countless mocking & twisted disingenuous offerings. Even if there’s a premise for argument sake.
So many more literate & evocative panelists who interject here, yearly, ...often see very few significant replies. ...But you get one or two debilitating & vile pizzmongers posting regular vitriol ~ even if there IS a solid point to be made it’s done by way of a derisive & abusive-until-counterfeit-virtuousness-works-better means, ...& what goes down? Why, they're served-up the floor like visiting dank dignitaries with rat hats and wolf blazers. Yet the apparel means nada & the mordant smirk moves no one.
ONLY the moot point prevails as it leads all who follow it like blood-shadow droppings, ...[dreamily] down into the land of Nod.
It’s a great inspiration for all those pernicious pizzmongers to come, ...to know they face such a well-gessoed palette on which to sssscrrrape and molest all the best laid notions.
HEP
...t's like a greasy pole....
...waiting for updates to the www.dnaprint.com site; ie, investor relations...& perchance more key disclosures. ...perchance.
OT/Chrisbaskett,
Gotcha. Sounds like a groovy pond.
I looked over d'field...
& my money's on DNAG!!
Chrisbaskett:
Sounds great man.
Our red radishes had such thick skins...we had to cut them and spoon out the meat to enjoy them. Never had that happen before, ...although we used the same seeds. Hmmm. That, and the snow peas never really took-off. Something about the soil, I suppose; ...but it certainly seems like a great bed of soil. All else is rockin' in the free world...&, Oh, the colors we've had around the house this summer. Almost time for fresh garden tomato &/or carrot/beet juice;
...yeah, babee!
One thing: What's a Shebumpkin? Coi?
Bag8ger:
You've got new mail.
lol, Chrisbaskett,
...nicely said.
In the interim, ...howz the garden bro?
it did work the first time i went to it, Arch, ...but now it shows an "error" message. funny title for the board though. who came up with that? quick thinkin'! 3 cheers for the nag that can RUN!! Giddee-up!!
man, that's an excellent query. i can hardly wait for the reply....
thank u sir,
may i have anuther?
...but the question iz,
will they still disrespect us in the morning?
>>DNAPBODperseverance
;o)
Way OT, ...a spleen drippin’ Offer!!
Listen Here!
I got a plan to put sticky feet on chickens!
No, wait now!!
No sht, chickens! The science is happenin’, the chickens suffer no ill effects ~ THAT’s the real science. The algorithm of choice! Why sticky feet, you ask? So we can get twice as many chickens in the barn. All these cages stacked hundreds on top of hundreds, chicken defecation all over...one’s upon the other. NOW, with this new “Threw Put” technology, ...we can put chickens on the walls; AND...get this...the ceiling. Yes, they actually like it up there, ya’ll can tell. How do we put them up there? Well first...well first we *throw them, ...then they stick...& they stay *put, ...then eventually they...jus’...adjust to it...and walk around up there, ...all happy & a’cluckin’ & and peckin’ sticky feed...like a ho-down at the Jeever’s farm!
Now this’eers the plan. I’m havin’ and IPO. Man I got plans. M’girl Friday’ll answer the phone...when we git it hooked-up. Oh, the plans galore! This thing is goin’ to the moo....n . We will be puttin’ sticky feet on chickens all over the world, ...and oh, the deals we WILL hatch. You can rest THAT ASSured! You ain’t seen nuthin’ like this. This ground floor, fledgling, space-age technology for the health and well-being of all civilization WILL provide the hottest of all up-&-comin’ sectors a “personalized” hen-peckin’ benefit for all humankind.
I will be your CEO AND CSO, until I can unearth some astute and dodgy ol’ silver-spooner with an attitude like the bad guy in the movie “Scanners”...so he can tell you to “SEND MONEY [snarl...] and get out there & VOTE consolidation,” of course! CUZ ARE WE GONNA CONSOLIDATE BABEE!! Till those mooooooooo...n cows come home!!
So send money, lots & LOTS of earnest investment trust; care of my RB email address. I’ll send your shares via USPS; ...don’t let the odd fact that they look much like squares of TP twist ya all up in the barn pardners, ...it’s an illusion, a trick of the eye, ...these are bona fide shares of the great Do Not Asphyxiate the Pigs Company, of Dwight City, Nabraska.
Yeeee-haaaaaw....
& remember the words of the great Jerry Lee Lewis!
Well, I said come along my baby, we got chicken(s) in the barn,
whose barn, what barn, my barn
Come along my baby, really got the bull by the horn...
We ain't fakin', ...whole lotta shakin' goin' on.
JMHumbleParodiedO
Just havin’ a little fun, ...at my own expense.
This is how it feels sometimes:
[from Paradise by the Dashboard Light]
Radio Broadcast:
Ok, here we go, we got a real pressure cooker
going here, two down, nobody on, no score,
bottom of the ninth, there's the wind-up and
there it is, a line shot up the middle, look
at him go. This boy can really fly!
He's rounding first and really turning it on
now, he's not letting up at all, he's gonna
try for second; the ball is bobbled out in center,
and here comes the throw, and what a throw!
He's gonna slide in head first, here he comes, he's out!
No, wait, safe--safe at second base, this kid really
makes things happen out there.
Batter steps up to the plate, here's the pitch--
he's going, and what a jump he's got, he's trying
for third, here's the throw, it's in the dirt--
safe at third! Holy cow, stolen base!
He's taking a pretty big lead out there, almost
daring him to try and pick him off. The pitcher
glance over, winds up, and it's bunted, bunted
down the third base line, the suicide squeeze in on!
Here he comes, squeeze play, it's gonna be close,
here's the throw, there's the play at the plate,
holy cow, I think he's gonna make it!
STOP RIGHT THERE!!
[chuckle/sigh]
nicely said, thanx eb0
Cosmically.inclined.one:
Alrighty then. No harm, no foul.... Groovy.
According to Flip, on the RBDNAP board, they DID have a tent and some breakfast for the shareholders, ...so it was not too far off the truth. Hey, ...double trouble man! I’m pleasantly surprised that they took it up a click or two this year.
Another couple hundred bucks...and they could have had the setting I proposed...chuckle/sigh.
Perhaps NEXT year.
Be Good Cosmic....
Jeez, cosmiclefeform:
...probably by now you've come to find that I was being facetious...and well, ...imaginative for sake of wishful thinking...when I posted that drivel on the RB board this morning.
Sorry for the misunderstanding, man. I thought it would get a grin at best. [Sorry I waited until now to look in on the Ihub board, to find your post.]
Although that setting is certainly what I would aim to provide if it were my meeting to manage. Inexpensive, yet effective; & a show of respect & courtesy. It's the least a public company on the World stage should offer it's visiting shareholders...once a year.
But that's jmho.
Be Well, JB
stuff 2 look at
http://www.sciencenews.org/articles/20050409/bob9.asp
Code of Many Colors
Can researchers see race in the genome?
Christen Brownlee
The first in a two-part series on race, biology, and medicine
Historian Frank W. Sweet of the University of Florida in Gainesville recounts the classic rags-to-riches tale of Louetta Chassereau, an early 20th-century socialite. As a baby, Chassereau was adopted from an orphanage by a well-to-do white couple. She later married a wealthy man, and her children attended the best white-only schools.
Blend Images
However, a dilemma developed when Chassereau's husband died, leaving everything in his will to his beloved wife. Enraged, her husband's relatives contested the will. The reason? Although people in her community had always thought of her as white, "Louetta had started life as a Black baby," says Sweet in a recent essay. Because Chassereau was born of black parents, according to an antimiscegenation law of the time, Chassereau legally could marry only a black man. The white family claimed that she had no right to the fortune.
Although the courts ruled in Chassereau's favor in 1940, saying that her life's path had made her "irrevocably white," her in-laws remained unconvinced.
In the past 65 years, defining race hasn't become less ambiguous. While it's abundantly clear that race exists from a sociological standpoint—racism wouldn't take place without it—does that categorization also exist biologically?
Current genetic research hasn't yet come up with a black-and-white answer. Nevertheless, understanding the biology underlying perceptions of race could have dramatic implications.
Racy subject
It's difficult to get most scientists even to say the word race when referring to people. That's because in traditional scientific language, races are synonymous with subspecies—organisms in the same species that can interbreed but nevertheless are distinctive genetically.
PhotoDisc Red
Many species split into subspecies after being separated geographically for an extended amount of time. During generations of genetic mixing within but not between the isolated groups, some of each group's genes develop slightly different versions, or alleles. Scientists often use a rule called Wright's F statistic to judge whether separate groups are actually subspecies. If 25 percent or more of one group's alleles are different from another's, then by F-statistic standards, the two groups are considered subspecies. A difference of 100 percent would separate them into distinct species.
Subspecies, or races, exist for many animals—for example, the alleles in some populations of grey wolves score up to 70 percent on the F-statistic scale. However, the groups of people considered to be of different races have allelic differences of at most 15 percent, too little to constitute subspecies.
To the nonscientist, however, race clearly is a meaningful term, says Vivian Ota Wang of the Ethical, Legal, and Social Implications Research Program at the National Human Genome Research Institute (NHGRI) in Bethesda, Md. The concept seems to depend on a collection of physical features, "like a checklist," she says, "so that people can categorize each other into groups." Items on the list might include skin tone, hair texture, and the shapes of eyes, noses, or lips.
Most people don't carry a conscious perception of the checklist. Wang says that race has a lot in common with Supreme Court Justice Potter Stewart's famous definition of pornography: We know it when we see it.
About 100,000 years ago, defining race wasn't an issue—all early humans lived in Africa and had similar characteristics. That relatively small population of recently evolved humans carried the majority of alleles present in people today.
But over the next 50,000 years or so, as humans separated into groups, slight differences among populations crept into the genome. First, as waves of emigrants left Africa and spread throughout the world, our ancestors took slightly different groups of alleles with them. Just as each handful of jellybeans scooped out of a jar might have a different mix of flavors, every group of migrant humans carried a slightly different array of alleles.
Later, when roaming humans settled into permanent residences on different continents, new genetic mutations gradually built up within groups as they adapted to their distinct environments. Because people mated most frequently with others from the same region, each population developed its own set of mutational differences, some influencing survival and some being just genetic quirks.
Share, share alike
According to Lisa Brooks, a geneticist at the NHGRI, the genetic differences within each population take several forms. Some people have certain segments of DNA wedged within stretches that run without interruption in other people. Conversely, genetic pieces present in many people are missing in others. Also, stretches of DNA can be flipped so that they read backwards, or they might contain small repeated segments, called microsatellites, that vary in number from person to person.
The genetic variation that most interests Brooks is called a single nucleotide polymorphism, or SNP (pronounced "snip"). It's a one-letter change in the string of DNA components that go by the letters A, C, G, and T. For example, where one person might have a section that reads TAAACA, another person's section might read TAAAGA.
Most SNPs occur in places in the genome that aren't used for making proteins—the so-called junk DNA. But the few SNPs that land squarely in a gene or in a regulatory region near a gene can alter characteristics influenced by that gene—for example, physical appearance or propensity for disease.
Sets of adjacent SNP alleles in the same chromosome region are called haplotypes. Through a collaboration called the International HapMap Project, researchers around the world are recording and analyzing the SNPs present in four populations: Utah residents with European ancestry, a Nigerian population called the Yoruba, Han Chinese in Beijing, and Japanese inhabitants of Tokyo.
Although the study wasn't designed to probe the genetics of race per se, one of the major findings from HapMap so far, says Brooks, is the enormous similarity between the four groups' SNP patterns. In an interview, Brooks illustrated her point by drawing on a piece of paper four largely overlapping circles, with only slim slivers of each ring peeking out at the edge.
RACING IN CIRCLES. Research has shown that the range of DNA variety in populations, represented here by circles of various colors, overlaps by about 85 percent. Only a few of each group's DNA snippets are unique.
E. Roell
Brooks points to the large area where the circles overlap and explains that about 85 percent of variation is shared by all populations. By default, the genetic variation in the slivers includes the alleles that lead to differences among populations, including those on the typical racial checklist. "Superficial traits, like skin color or hair texture, aren't typical in their patterns of variation of [most of] the genome," says Brooks.
This concept can be hard to grasp for people who believe that racial groups are fundamentally different genetically, says Georgia Dunston of Howard University's National Human Genome Center in Washington, D.C.
Dunston studies how the human immune system distinguishes between a person's tissues and foreign material, such as a splinter, a bacterium, or a transplanted organ. The genes responsible for this recognition are called histocompatibility genes. Having similar histocompatibility genes is a major factor in successful organ transplants.
In tissue matching, a bastion of genetic differences between people, Dunston finds that race is not the determining factor. "We have this thinking in America that there are some deep differences in biology between whites and blacks, that tissue in whites is more similar to [tissue in] whites than tissue in blacks," she says. "But when we look at the genetics, because of the tremendous variation in all groups, and especially in the group called 'black,' it's not uncommon at all to find two blacks who could be very different from each other."
In some cases, a black organ donor, Dunston adds, can better match a white recipient than a black one.
What’s the difference?
Nevertheless, no geneticist can overlook the slim fringes on Brooks' overlapping-circles diagram. According to Brooks, the longer people in a population have mated in close association, and so share the same ancestors and kin, the more similar will be their genes—and all the traits they encode—in that 15 percent of the genome.
PhotoDisc Green
Race and family origin aren't entirely synonymous in modern times, when people can relocate around the globe. However, many researchers have found that the distribution of certain genetic variations can lump people into ancient ancestral groups uncannily similar to what nonscientists call races.
For example, Noah Rosenberg of the University of Southern California in Los Angeles and his colleagues published a study in 2002 that analyzed the number and type of microsatellite variations in the DNA of 1,056 people from 52 populations around the world.
Rosenberg's team masked any information about the study volunteers' ancestral backgrounds and then plugged the microsatellite information into a computer program that clusters people by genetic similarities. Six main clusters emerged.
After restoring individuals' ancestry data to the files, the researchers found that five of the six microsatellite clusters corresponded with geographic regions: Africa, Eurasia (Europe, the Middle East, central and south Asia), east Asia, Oceania (islands of the central and South Pacific), and the Americas (specifically native Americans). The sixth and smallest cluster linked to an isolated group of mountain-dwelling Pakistanis known as the Kalash.
The scientists weren't surprised that people's genetic mutations usually lump them into continental groups. For much of history, people have been land bound and so have mated mostly with people from the same continent.
However, Rosenberg says that he was surprised that he and his colleagues found it impossible to predict with certainty which combination of gene variants any specific person in each cluster had. The computer runs couldn't determine, for example, exact shades of skin color or types of hair texture for individuals.
"In a lot of classical anthropological views of race, race is thought to be a quality predictive of a large variety of traits about a person. We found that for any given person, it's not possible to predict accurately which [variant] they have at any particular site in the genome based on their group membership," Rosenberg says.
Neil Risch of the Stanford University School of Medicine and his colleagues recently used a similar method to come to a very different conclusion. Using microsatellite information from another study that had looked for a genetic link with hypertension in several U.S. populations, Risch's team ran data from 3,636 people through a computer program similar to Rosenberg's. However, instead of searching for clusters based on geography, Risch and colleagues compared clusters from the genetic data with self-described race/ethnicity categories.
The genetic data sorted into four categories—white, African American, east Asian, and Hispanic—which neatly matched what each person had checked on a form at the beginning of the study. Only five people had results inconsistent with their self-described race/ethnicity, giving an error rate of 0.14 percent, the team reports in the February American Journal of Human Genetics.
"This shows that people's self-identified race/ethnicity is a nearly perfect indicator of their genetic background," says Risch.
Racism realism
Risch's results have stirred up controversy among many geneticists. For instance, Mark Shriver of Pennsylvania State University in State College says that Risch's method "can overcluster people," making associations between individuals and their race that don't exist with other types of analyses. Shriver and others haven't found similar clusters when they applied a different computer program to similar data.
PhotoDisc Red
Shriver also contends that the study's separation of people into four racial groups shrinks the natural range of genetic variation, making people within each group seem more alike than they really are.
Rather than there being clear racial lines, says Shriver, "there's really a continuum of variation across the globe." If researchers sampled only people in Africa and Sweden, the genetic differences between the two groups would be striking. However, a sampling of people from Africa, Sweden, and everywhere in between would reveal only small differences between each population and its neighbors. "You won't see a place where you'll say, 'There's the racial divide,'" says Shriver.
Nevertheless, Shriver works with a company that uses what variation there is among populations to trace people's ancestry. The company, DNAPrint Genomics in Sarasota, Fla., starts with DNA from a customer's inner cheek. After comparing the sample's genetic markers with those in a data set collected from people around the world, the company estimates what percentage of the person's ancestry is African, East Asian, European, or Native American.
The results can be surprising. When Shriver, who considers himself to be white, analyzed his own DNA, he found that it contained the Duffy null allele, found only in descendants of sub-Saharan Africans. "The test estimated that I have 11 percent west African ancestry," says Shriver.
In spring 2003, Shriver and his colleagues applied the test to an urgent task—they were instrumental in catching a Louisiana serial killer. After analyzing DNA from semen at the crime scenes, Shriver and his colleagues estimated that the killer was 85 percent African and 15 percent Native American. Officers eventually arrested Derrick Todd Lee, a black man whose DNA matched that left at the scenes. As testament to the uncertainty of eyewitnesses, Lee was convicted although several people had reported seeing a white man at the scene of several of the murders.
Although an ancestry test had put police on the right track in this case, Shriver expresses concern about the test's potential for misuse in other social realms. One danger, he notes, is attempting to correlate ancestry with qualities such as intelligence, athletic performance, or musical ability. "It's hard to know what the right use is. We have to be vigilant," he says.
Researchers may never nail down a precise connection between race and genetics, but there's little chance that the concept of race will ever go away, says Charles Rotimi of Howard University's genome center. Over the centuries, some people have used race to set discriminatory categories and then give themselves privileges and take privileges from others. People who have been advantaged by racism aren't likely to give it up, Rotimi says.
"Look at the Hutus and the Tutsis," he adds, referring to two Rwandan tribes that have been fighting each other for decades. "You don't need genetics to be racist."
Next week: "The Race to Prescribe"
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References:
Tang, H. . . . and N.J. Risch. 2005. Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies.American Journal of Human Genetics 76(February):268-275. Abstract available at http://www.journals.uchicago.edu/AJHG/journal/
issues/v76n2/41839/brief/41839.abstract.html?
erFrom=-807749556546761969Guest.
Further Readings:
Rosenberg, N.A., et al. 2002. Genetic structure of human populations. Science 298(Dec. 20):2381-2385. Available at http://www.sciencemag.org/cgi/content/full/298/5602/2381.
Shriver, M.D., et al. 2004. The genomic distribution of population substructure in four populations using 8,525 autosomal SNPs. Human Genomics 1(May):274-286. Abstract.
Shriver, M.D., and R.A. Kittles. 2004. Genetic ancestry and the search for personalized genetic histories. Nature Reviews Genetics 5(August):611-618. Abstract available at http://dx.doi.org/10.1038/nrg1405.
Sweet, F.W. 2004. The rate of black-to-white "passing." Backintyme. Available at http://www.backintyme.com/Essay040915.htm.
Additional information about DNAPrint genomics can be found at http://www.dnaprint.com/.
Sources:
Lisa D. Brooks
National Human Genome Research Institute
National Institutes of Health
5635 Fishers Lane, Suite 4076
Mailstop Code 9305
Bethesda, MD 20892-9305
Neil Risch
Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Noah Rosenberg
Program in Molecular and Computational Biology
University of Southern California
1042 W 36th Place
DRB 289
Los Angeles, CA 90089-1113
Charles Rotimi
Howard University
2941 Georgia Avenue, N.W.
Cancer Center Building, Room 614
Washington, DC 20060
Frank W. Sweet
Backintyme
30 Medford Drive
Palm Coast, FL 32137-2504
Mark D. Shriver
Anthropology and Genetics
Penn State University
409 Carpenter Building
University Park, PA 16802
Sarah Tishkoff
Department of Biology
Biology/Psychology Building
University of Maryland, College Park
College Park, MD 20742
Vivian O. Wang
National Human Genome Research Institute
National Institutes of Health
5635 Fishers Lane, Suter 4076
Mailstop Code 9305
Bethesda, MD 20892-9305
...did u understand the music, Yoko, or was it all in vain? _eom
way off topic [sorry]:
i know i'm taking a shot in the dark here, but...
anybody know something about n-Track Studio (the shareware, not the upgrade)?
i have a puzzle missing a piece, ...& it has chained me to creative motionlessness today.
tia,
jb
Bag
Well said, sir.
"...souls from despairing into the ignominy...."
wow
Chrisbaskett:
Good bud. ...Because pretty much everything that has been said on these boards regarding DNAP the past year has been weighed, measured and found wanting -- both the negative, because the negative is ALWAYS just too dawgone EASY to communicate, and the positive, because of the one-step-forward-one-step-back mannerisms of this company’s communication methodology(or lack thereof), ...some air HAS surely been let-out of whatever mo-mo that may have been developing here. Yep.
But THAT can change at a drop of a dime, IMHO. If a DIME is there to be dropped, & IF Mr. Gabriel & Dr. Frudakis et al. can somehow find a new way to tack in regards to informing down to their earliest investors without legal or sector liabilities.
I am somehow relieved by the news. But it is a puzzle, certainly.
It’s as if DNAP has been relegated to hiding in a fortified bunker 20 floors below some arbitrary law library or water treatment plant...& no one is allowed in or out without a security clearance that would make the Prez blush.
[lol] Keep ‘at Energy bro. Don’t loose your head.
Gcbr:
Funny you should use that [the mountain is beginning to move] phrase today.
I used that same notion in a brief analogy regarding our DNAP in the wee hours of just this morning's email to Bag.
lol
Energy & Endeavor,
JB
Open wide BIG Pharma:
~~
Pharmacogenomics could expand markets and revenues by defining new uses for existing drugs, "rescuing" drugs in development, managing product life cycles, and dominating niche markets. Better- targeted drugs also could reduce the massive marketing costs vital to blockbuster drugs.
* There are immediate clinical demands for pharmacogenomic products.
~~
http://ragingbull.lycos.com/mboard/boards.cgi?board=DNAP&read=321989
http://press.arrivenet.com/bus/article.php/598245.html
ot ~ MykelMan17X:
You said,
"I have this dreadful habit of wanting people to understand because anything can be taught to anybody if it's taught in the right way."
...That’s a magnificent notion, really.
The entire post is well said; on-topic,
but it’s THAT line, in its subtle oblige,
that cribbed me.
A57TBird
Back in the states in 3 months....
Well alright, we'll order you up some North American Springtime for your arrival.
Hopefully DNAP will have taken it to the next level by then.
...see u later Gunny.
ot ~ A57TBird:
I trust yours & yourself were able to be of assistance, as you had envisioned, and some hope was brought to the masses.
Good to hear you're back on that blessed rock in th' Ryukyus.
Ichigo Ichie,
JB
DNAP lil'blurb in BioIT-World today:
http://www.bio-itworld.com/news/021005_report7440.html
...not sure if this link has already been posted on any of the boards. sorry for the repeat, if so.
you're welcome Team.
Who here
...is Sisyphus, who is the stone, who is the hill, who is Odysseus, ...& who is Theseus? Who really gives a fck? Who doesn’t mind a lick? This is not my beautiful house, ...this is NOT my beautiful wife. Toodles droped in for a ruthless howdy. Good that DNAP rolled-out the red carpet for ‘im. It certainly is not an irony. It’s more like black tarnish on good 925 silver. $ there’s no fresh water to boil the aluminum in, $ there’s no fire hot enough anyhow. I can smell carbon in the air, yet it is not St. Crispin’s day. It is not St. Crispin’s day. $ Crispin Crispin shall THERE go by...for this time anyway. The trumpeters have let the pigeons fly, but the GOP Merino Wool camo-utility brigade has blasted them all out of the gray sky with AK-47s and 45/70s with Redfields. Nothing left of those birdies actually exploded by the 45/70 rounds. But so few o’ those cocktailed and hobnobbed cats can shoot anything smaller than a penned boar at the country club with a 45/70 that mostly the pigeons are machine gun fodder...and one guide with a 12 gauge and a bandolier full of 8 shot makes easy breezes of a baker’s dozen. The sneezes were all-out blitzkrieg this day, as the puppets danced and the more angstly bagholders shat a brick of concrete and rebar, ...but it’s only hay pennies...and it’s only January. Who said a calculated risk is anything but a bloodbath beside a bluish parallel universe beyond the sight-grasp of the limpid mortal coil driven to spit anti-peace euphoria and sodden gripper strips at the prettiest young babes aglow with vixen energy and coconut oiled limbs. Her mama’s Depends gave credence to matters of greater degrees than the mood shift of one DNAP board from Month to month. .04 was an eternity ago. I KNOW. .00whatever may be just another strip bar called Cappy’s with boarded-up windows across from a rather epic low-income trailer park, on the forgotten side of town...come February or September. The logic of Theseus has gone on hiatus, the technological confidence is in the side pocket and the cue ball is in the corner, ...ball in hand. Who’s got rounds, $ where are those noble missionaries to Gaul?
~~~~
He that outlives this day, and comes safe home,
Will stand a tip-toe when the day is named,
And rouse him at the name of Crispian.
He that shall live this day, and see old age,
Will yearly on the vigil feast his neighbours,
And say 'To-morrow is Saint Crispian:'
Then will he strip his sleeve and show his scars.
And say 'These wounds I had on Crispin's day.'
Old men forget: yet all shall be forgot,
But he'll remember with advantages
What feats he did that day: then shall our names.
Familiar in his mouth as household words
Harry the king, Bedford and Exeter,
Warwick and Talbot, Salisbury and Gloucester,
Be in their flowing cups freshly remember'd.
This story shall the good man teach his son;
And Crispin Crispian shall ne'er go by,
From this day to the ending of the world,
But we in it shall be remember'd;
We few, we happy few, we band of brothers;
For he to-day that sheds his blood with me
Shall be my brother; be he ne'er so vile,
This day shall gentle his condition:
And gentlemen in England now a-bed
Shall think themselves accursed they were not here,
And hold their manhoods cheap whiles any speaks
That fought with us upon Saint Crispin's day.
--- Henry V, William Shakespeare
[jmhdrivel]
http://ragingbull.lycos.com/mboard/boards.cgi?board=DNAP&read=319377
the moon, & the tides roll on
...the pebble & the pond....
DNAPerseverance
m-16: Aren’t fledgling endeavors always that way? Slow going and resolute. & aren’t there always naysayers...until the proof-pudding smacks-them-in-the-side-of-the-head with remarkable reality?
Overnight success, like the sapling that grows without hardship & lacking the strength for longevity through the thick & thin of it, is usually fleeting.
Can you, in any way, see a furthering process coming out of DNAP? Financial issues aside, just the act of forward progress by the principals? If so, then what’s your beef, really?
I get hammered on occasion by the compensation of the BOD, ...but it’s comparative. Maybe not in regards to shareholder satisfaction & revenues, but they look to be working for their extravagant incomes. & extravagant income IS the call of the day ...these days. It’s tough to swallow, yes, but they put themselves in a position of looking after their own interests. & there is always an air of pomposity in well-heeled business practices. No?
bigdrive:
smarter than what?
the matador's smarts are relative to the bull with which [whom] he's facing-off.
[imho] since i have no bona fide idea why so many handles are over here and over there, for so many hours in a day, seemingly without any other reason for living, pointing out the obvious negative possibilities, ad nauseam/adumbrate, of a fledgling r&d company essentially trying to make ends meet and set the tone for a spanking new sector,
...i suppose i find myself at a disadvantage.
& so i imagine you will have to get used to disappointment.
peace, out