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Aw shucks, Bigworld ... don't you realize that synDNA is the answer ... I have it on good authority (right from this thread) that our time is getting nearer and the train is a'fixing to leave the station and going to the moon.
Malcolm and cronies accomplished exactly nothing. Zip. Nada. Nothing.
Of course, Happy, the PP suit doesn't prevent CYGX from doing additional testing and development. Those are prevented by the lack of funds to perform them. Just one more example of how the CYGX back shop gang is far more proficient at their jobs than the front office mob.
As far as the PP suit, is it possible that CYGX is shooting itself in the foot in order to prevent PP from getting more out of the lawsuit. That does not seem to be in the best interest of us shareholders. Strange that management doesn't have any problem with granting itself tens of millions of share options but isn't willing to do what ever is necessary to recover from its mistakes in granting licenses to underqualified parties (if that is the case with PP).
It seems that we will all be far better off if CYGX settles the claims that folks have against them and get along with the business of getting something to actually producing cash flow instead of a lot of hot air being belched at us.
Killer Bees to the World Series
OT: I hadn't thought about that in many years, although I also still use the phrase. Brings back a few more memories ... thanks.
Although we love Minute Maid, it doesn't evoke the vivid recollections that the Dome does. Charlie was just one of many great characters that flowed thru the organization. I think he still holds the record for the number of Buffalo Wings eaten in a twelve inning game ... rofl.
Do I miss those times? Of course. I just have to be content with the fact that I was there and savor them as they return to my memory. I asked Doc about going back next year and he says that if I keep improving, he may be able to clear me for next summer or fall. If not, I've had enough fun for a half a dozen folks, so I'm not going to gripe too much ... LOL.
Wonder when CYGX will go after stroke and other memory eating proteins?
GO STROHS ... Of course we have been following every moments of the play-offs. This is only the second time I have not been in the club house for the post season ... I miss having the champaign sloshing around in my boots ... remember the shots of Charlie Kerfield soaking Dierker and me?
I think I'm going to get a new TV for the Series ... take some of my ATAHQ profits and get a 60" to watch them on. SC is still celebrating.
We didn't get any tickets in the lottery and when I spoke to friends in the organization, they simply asked ... "Hogger - who?" ROFL
Good luck Scooby (and all other in ther path of Wilma) ... yall stay safe and don't take any chances. We just received our initial activation notice. Here is the latest discussion of Wilma. It was released about three minutes ago. Again, Scooby, good luck and God Bless ...
000
WTNT44 KNHC 201500
TCDAT4
HURRICANE WILMA DISCUSSION NUMBER 21
NWS TPC/NATIONAL HURRICANE CENTER MIAMI FL
11 AM EDT THU OCT 20 2005
WILMA CONTINUES ON ITS WEST-NORTHWEST HEADING...295/6...WHICH
REMAINS A LITTLE TO THE LEFT OF THE SHORT TERM GUIDANCE. FOR THIS
REASON...THE HURRICANE WARNING HAS BEEN EXTENDED SOUTHWARD ON THE
YUCATAN PENINSULA. RAOB DATA IN FLORIDA AND TEXAS SUGGEST THAT
RIDGING IN THE GULF IS WEAKENING AND IT IS STILL EXPECTED THAT
WILMA WILL BEGIN TO TURN TO THE NORTHWEST OVER THE NEXT 12 TO 24
HOURS. DATA FROM THE NOAA GULFSTREAM JET ARE BEING INGESTED INTO
THE 12Z MODELS AND WE WILL SOON SEE WHAT IMPACT THESE DATA HAVE ON
THE TRACK GUIDANCE. THE BASIC SYNOPTIC SCENARIO IS UNCHANGED.
RIDGING IN THE GULF IS EXPECTED TO CONTINUE TO WEAKEN SLOWLY OVER
THE NEXT COUPLE OF DAYS...WITH WILMA ACCELERATING NORTHEASTWARD
LATE IN THE FORECAST PERIOD AS SHORT-WAVE ENERGY DIGS SOUTHWARD
AROUND THE BACK SIDE OF A LARGE LOW-PRESSURE SYSTEM OVER THE
NORTHEASTERN UNITED STATES. THE MOST SIGNIFICANT CHANGE TO THE
MODEL GUIDANCE IS A GENERALLY SLOWER RECURVATURE AND ACCELERATION.
AS FAR AS THE FLORIDA THREAT IS CONCERNED...THE MAIN FOCUS OF THE
THREAT REMAINS FROM CENTRAL FLORIDA SOUTHWARD THROUGH THE
KEYS...AND IT IS STILL TOO EARLY TO NARROW THAT DOWN ANY FURTHER.
SATELLITE IMAGERY INDICATES THAT THE INNER EYEWALL CONTINUES TO
WEAKEN...AND EARLIER RECONNAISSANCE DATA SHOW THAT THE HURRICANE'S
HIGHEST WINDS ALREADY ARE ASSOCIATED WITH THE OUTER EYEWALL.
ALTHOUGH SOME ADDITIONAL WEAKENING MAY OCCUR THIS AFTERNOON...
RE-STRENGTHENING IS POSSIBLE OVER THE NEXT 24 HOURS AS THE EYEWALL
REPLACEMENT CYCLE PROGRESSES...AND WILMA COULD REGAIN CATEGORY FIVE
STATUS BEFORE IT REACHES THE YUCATAN. WILMA IS NOW EXPECTED TO
SPEND ENOUGH TIME IN OR NEAR THE YUCATAN TO RESULT IN A
SIGNIFICANTLY WEAKER STORM IN THE GULF WHEN IT APPROACHES FLORIDA.
FORECASTER FRANKLIN
FORECAST POSITIONS AND MAX WINDS
INITIAL 20/1500Z 18.4N 85.5W 125 KT
12HR VT 21/0000Z 19.1N 86.2W 130 KT
24HR VT 21/1200Z 20.3N 86.9W 140 KT
36HR VT 22/0000Z 21.2N 87.0W 130 KT
48HR VT 22/1200Z 22.0N 86.2W 120 KT
72HR VT 23/1200Z 24.0N 84.0W 105 KT
96HR VT 24/1200Z 28.5N 78.5W 70 KT
120HR VT 25/1200Z 40.0N 68.0W 60 KT
Yet Tatonkano, I do know it to be true. I was one of the folks who tried it. Strangley, I ran into at least two of the others who tried it and we all had similar, long lasting results.
A few years ago, when "chipped" ran this board, he stated also in private messages to me that the herpes formula worked. He knew people who had used this formula and never had further outbreaks. Do you know this to be true.
As for the following statement, I must disagree with you ... management has managed to get themselves a crapper-load of shares and many millions of options ... they have indeed delivered ... to themselves. And as far as getting a closer ... keep your hands off Clemens ... lol.
Anyway, this management team has delivered nothing but repeated pr's. We could seriously use someone who can close the game out.
Happy, the kids and I are all just standing pat. We have all reduced our positions and have ALL made money on our stock. After the first posts concerning an IND submission in December, we decided to increase our holdings again, because we KNOW that the herpes and anti-inflamatory works. Although the verbiage was familiar, thanks be to Arnold for his research.
Guess nobody over in the front office can write new verbiage for the reports ... LOL.
I'd really like to see the front office provide the back-shop with the capitol to FINISH the research on something instead of jumping from horse to horse in order to stir up interest and keep the doors open. Maybe we should surprise the front office boys with an extra 18 million share option package.
I'm still concerned about why the IND has not been submitted in the past ... and I hope nobody is stupid enough to claim that it has anything to do with the synDNA ... that appears to be nothing other than a meritless lame smokescreen.
Happy, give me a call ....
BW, is that the same GE that was going to provide a great big capital boost to CYGX? Is their failure to provide that money something that we should take as a weather indicator?
General Electric is an excellent weather vane for the direction of the US economy.
Good Lord, Scoob ... you have just taken melodrama to a new low ... and managed to border on sacrilidge simultaneously ....
When and how I really cannot say, I am not god but just a servant.
P.S. On this night, someone will betray me.
Wazzamatter P-NESS, you afraid that someone will start reposting your slightly off target posts? Are you really afraid to join the rest of us and put up a wild guess? We've exposed ourselves to being the butt of a few good belly laughs, but all of us have missed our guesses many times in the past, and if my memory serves me, I think you have reposted more than a couple of posts from other people ....
Arnold, please stop rubbing Scooby's nose in those crocks of crappe from the past. Just because he has totally missed every prediction and has hyped every PR in the past is no reason not to give him an opportunity for a fresh start.
And please stop reposting his actually posts where he has totally missed the train as it pulled out of the station as it headed for the moon. There is no reason to impeach someone with their own verbiage ... okay?
Now, stand in the corner and repeat three mea culpa's .... rofl
Actually Holycow, you may be getting the wires crossed with former CYGX employee Maury Fogle ... remember him? Since he left we have not had anything submitted on time and the PR's seldom make sense. Wonder what he is doing now?
This is a hard one Arnold ... I still believe that if there is ever an epidemic of fecal collation in the management, we have products either just entering the approval pipeline or prepared to enter when LW gets one of the big financing deals we have heard so much about over the past several years.
Unlike many, I still have great faith in the potential of a couple of the products ... herpes can be a very major revenue producer if the front office gang overcomes severe cases of rectal cranialitis and finds a way to get it to market. The many, many applications using the ICAM goo would bring PPS up into the $3 - 5 buck a pop range.
Unfortunately, I just don't think our front office gang can bring the works of the very blessed and brilliant back shop gang to the market. So, I suppose that will have to be set aside when making prognostications ... so here goes:
With current management:
SynDNA works ... $.15 - .60 a share
SynDNA doesn't work ... $.15 - .60 a share.
Well ... even SnyDNA will have to be marketed ... so, if we see the academics and penny stock peddlers give way to a first class bean counter and a vaccuum cleaner salesman that will change to:
SynDNA works ... $5.00 - $10.00 a share
Syndna doesn't work ... $.25- 1.00 per share
Hey happy, wazzzup duuude? I just got a break and am sitting here basically monitoring and waiting for some folks to do their recon ... we gotz a little mess brewing over in East Texas and we is doing sum serious praying what thet dam don't break. I'm on the second deployment ... I'd forgotten how well firemen eat (first assignment this time) ... LOL.
Guess it'll be the MRE's again. At least they are a lot better than C-rations ... which weren't too bad with enough Tobasco ... you young fellers really missed getting to live on them ... ROFL
CYGX got next to nothing in the way of WX ... no damage at all. I asked one the the local cops to check it out as he drove by and he called on the radio and said it was all ok.
I must admit that I am shocked that a couple of the rainbow warriors have totally failed to tout the new SynDNA as a cure for both hurricanes and hissicanes ... maybe they haven't been told about that yet. I just wish it would cure my cel phones ... danged blasted SIM card went out yesterday and I won't be able to get a replacement for a few days ...
Hey, has anyone ever answered your questions about the ISIS 2302 vs ICAM stuff? I probably shouldn't ask because I have yet to see any of the RW's give an intelligent answer to anything.
If you get bored and want to relive your somewhat checkered past, we could use a couple of guys with your MOS down here right now, sir. LOLOL For two cents I'd ask the CG of I Corps to recall you ... and I'll bet your wife would provide the two cents ....
Good morning Happy, I'm getting ready to deploy. It's been almost non-stop meetings this week. As of the moment, it is looking like we dodged a fatal bullet, but we're still probably going to get a pretty good flesh wound out here ... LOL. If we don't get over Cat 1 winds here, we'll redeploy to FEMA and Army HQ immediately after the blow dies down.
I used the CYGX coordinates and unless Rita makes a major jog, they will get nothing worse than Cat 1 winds and being on something other than ground floor, they should not have any "major" water to contend with. In our conference call a few minutes ago, we remain very concerned about a jog to the left as she makes landfall and then there are a plethora of scenarios that do not bode well for the greater Houston area. I think it is all Ronald Regans fault ... has something to do with getting Gorby to pull down that wall ... or maybe, just maybe we can blame it on JFK ... you know, "to the moon"... LOLOL.
As for the synDNA and conventional DNA prices, I really wish someone would post the current bids and asks for clinical grade and other grades. I just can't find anyone paying the prices which are being touted. Last time I spoke to anyone at CCSA, THEY WEREN'T EVEN IN THE CURRENTLY TOUTED BALLPARK.
I still hang onto the hopes that began with the herpes and anti-inflamatory stuff. Although the herpes cure may have some questions (in retrospect), we have ample anectdotal proof of the effectiveness of the anti-ICAM ... or was it the Isis 2302 ... hmmmmmm. LOL
Good luck to all who are getting ready to dance with Rita ... she does a mean Cha-Cha and she loves to step on her partners toes ... sorta like Sasha.
Down with the power mad albatross .... arrrgggggg
or
Nothing showing but the chimneys ...
You're pretty close, happy. CYGX started (and for several years operated) from the front room of one of the founders. Ditto for AVGI, except that arrangements were made very early to have testing and the scientific stuff done at one of the worlds premier vet schools - Texas A&M. Additional work would have been done at one of the worlds premier pharmas in Taiwan, Canada and the good old U-S of A.
Look, the bottom line to the AVGI suit was that MS and LW simply did not like some of the folks involved and decided that they could attack Waldroff (a man who had never done anything other than assist and help finance CYGX - nice payback, huh?) and if successful, they could get rid of the folks at AVGI that they didn't like. Never mind that there was a contract in place. Anyone who was not in the court room cannot address what the suit was about ... at least not with any credibility but that probably won't stop any of the apologists for management.
You said something earlier that really worries me. The pattern seems to indicate that there is some problem related to IP belonging to others. Did that have something to do with the fact that CYGX got crossways with everyone involved with herpes? I hope not, but if that were to be true, then, somebody gotz a lot of 'splaining to do.
And the good news is that Katrina will probably not take as much of my time so I can give this board more attention. LOL.
Hey Arnold, just when we thought we had seen the worst of it all, even Old Sol decides he doesn't like us. Today has been the most difficult day for radio communications (especially in the HF bands) that I have seen in many, many years. We have for the most part simply been blacked-out. We're just starting to hear signals from the Northeast US, but they have those wavy sounds on them. Remember how they would be when you had a large aurora borialis out in the North Atlantic ... LOL.
I suppose we will start to catch up tonight with all the traffic that is piling up. I think I may have reached a small peak in frustration a little while ago ... oh, well, I didn't like those headphones anyway and new ones don't cost that much ... and the wall actually looks pretty neat with those little dents in it ... roflmao@me.
I guess that if you read the following, you can get very angry at Bush, the Governor of Rhode Island and of course the Head Chef at Brennens ... now we know how bad FEMA really is ... look at what they did to the sunspot cycle ...
Powerful Solar Flare Disrupts HF Communication
NEWINGTON, CT, Sep 7, 2005--One of the largest solar flares on record occurred today as a very active solar region 808 produced a powerful X17.1 flare--a "severe" or R4 event on NOAA's R1 to R5 scale. NOAA's GOES-12 satellite observed the flare at 1740 UTC. R4 events typically occur about eight times during each 11-year solar cycle, and today's was the fourth largest in 15 years.
"This event created a complete blackout of high-frequency (HF) communications on the daylit side of Earth," NOAA's Space Environment Center (SEC) reported. "Communications used by emergency services along the Gulf Coast may have experienced problems due to this flare. Low frequency navigation systems may also have experienced a period of significant degradation." R4 events also can disrupt satellites.
The effects of the X17.1-class solar flare began at 1717 UTC, peaked at 1740 UTC and ended at 1803 UTC. X-ray flux exceeded M5 at 1726 UTC.
A very bright and fast coronal mass ejection was observed, but the material was not Earth directed. An S1 to S2 is expected following this eruption, but it won't begin until late today or early September 8.
Over the past two weeks, the same active region of the sun has produced a series of significant solar eruptions as it made its passage around the back side of the sun. "Significant eruptions are expected in the coming days," the SEC said. "Agencies impacted by space weather storms may experience disruptions over the next two weeks. These include spacecraft operations, electric power systems, HF communications, and low-frequency navigation systems."
Times like these make me grateful that I'm a fierce independent and think both parties are at least somewhat out of touch with reality. Glad to see we have a moderator ... thanks to junkmasterq for taking on the job.
As I posted before Katrina came ashore, we were activated Sunday night (28Aug2005) and have been providing communications support for the brave heroic folks on the ground in NOL and across the Gulf Coast. If you could monitor the military, FEMA, etc frequencies, you would have your chest swell up a bit as you hear the actual happenings in the disaster area. The current crop of young Americans are a blessing. Then there are the miscreants (sp) who are just the opposite.
I've managed to find a new hero ... General Honore. One of the most level headed, honest, candid men America has produced in recent years. Isn't it wonderful that we always seem to have someone like him come along.
The new technologies are proving to be a mixed blessing. Communications have not been what many expected. Cel service was one of the first victims. Satelite services just require too much electricity for prolonged operations. In the afteraction analysis, we may find that we still need a pool of radio operators who can use CW (Morse Code) to communicate. Some of us old geezers were the only ones who could penetrate propogation and other obstacles and could get messages thru faster than the newer modes of emission.
We still have S&R (Search and Rescue) operations going on. Recovery is just starting and folks, nobody knows what that will produce, but it seems safe to expect it may well be the greatest natural catastrophy in recorded US history. We've had many of the S&R personnel report that they were marking houses and other points containing dead. Many of those voices have not been strong and steady, but they keep on keeping on. God Bless them.
I would like to encourage everyone of us to contribute as best we can. On those rare occassions when I have been able to watch TV reporting, there are some of the saddest stories I have ever seen. I've had tears in my eyes while handling many of the messages both into and out of the effected areas. Even being 'in the loop' we still have several friends and acquaintences not yet accounted for. All of our known family evacuated ahead of the disaster.
I have another hour until I go back on, so time to grab a bite and thank God for strong coffee ... lol.
Well, wish I could look forward to seeing you ... LOL. I'll probably go to one of the Houston Area Armories or Air Bases ... that's the usual routine. I'm getting as little too old for the field work ... LOL. If only CYGX would identify and fix the old age gene and the CRS defunct protein, I'd be swinging again ... If I go into the disaster area, it will be after tomorrow morning. (hopefully)
I'm really afraid of what is going to happen this time. The biggest threat is those levies. If a few of them are breached, it is unthinkable. Some of the folks at the NHC, FEMA, MARS, etc have been passing along some very scary scenarios.
Thanks for the warm wishes ... they are appreciated and we need them.
73 es QRT
It certainly was and it looked good and everyone was touting how much higher it would go with someone with Malcolms credentials at the helm. Some of us even speculated that he might be able to be almost as good as the only real businessman we ever had at the helm. (LM) As for having to go back seven years, that is part of the problem ... have we been floundering for that long? You'd think such giants of industry such as MS and LW would have us much higher, wouldn't you?
hogger you know the 3.00 a share was a spike
and you have to go back 7 years
We then watched CYGX slowly, surely drop to that $ .03 you mentioned. Although I didn't get any of the threepence stock, I did load up at a nickle and guess what ... I've made a lot of money on CYGX and still have stock to spare. 1200 - 2000+ percent isn't a bad profit, junior. Oh, and just to let you know, I didn't buy any of that $3.00 stock, but I did buy some pretty expensive (for CYGX) shares and regretted them. Now I've told you about my stock purchases which was none of your business, so is it true that you prefer members of your same sex. You don't have to tell anyone that, but as long as we're allowing others to stick their noses in each others business, I thought .... hmmmmmmmmmmmmmmmm
Well, we've just been activated to deal with Katrina, so off we go .... maybe I'll see Happy and some of the others at the bunker .... roflmao@littlegdepc
Now are you ready to answer our simple question about how much has CYGX dropped from its high since the current crew took over? Looks like real successful experience doesn't it?
We can buy little gdepc books, send him to school and what does he do ... eat the covers off of them.
He just hasn't been around for all of the other great events that were to take place and then just drifted off into LaLaLand. And if he thinks we are bashers, he should have been here for some real 'Bashers' like Shell, Scion, Salem, Greystoned and all of that group. They would have probably driven him to injesting frozen shrimp embryos ...
And he wasn't around for the plethora of great financing deals, either. Hey, what happened to this latest barrage of great wealth seeking out CYGX ... uh, First Montauk, GE, the Taiwaneese, etc, etc, etc. All of those really paid off didn't they.
The SynDNA offers great opportunity, but so have all of the rest. $5.00 per share would look wonderful and there would be a lot of celebrating around the hoggers household.
Wonder why little gdepc just won't address the great record of the current management ... do you think he has bet the kitchen sink and is terrified at the return so far?
Hey junior, you have hit the nail on the head. Apply the same question to the group running CYGX and guess what ... you get exactly the same answer ... zip, nada, zilch, none ... roflmao. Just which CYGX management crew has ANY experience running a biopharm ... Now are you ready to answer our simple question about how much has CYGX dropped from its high since the current crew took over? Looks like real successful experience doesn't it?
soloman we all know it is easy to be a back seat driver or a monday morning quarterback and that is exactly what you guys are all about
any back ground running a biotech company from your crew
Here is the latest NHC projection ... guess Happy and the family have either departed or gone to the NCWS (National Cyto Watchers Society) bunker with its twenty-two feet thick cement and steel walls. If worse comes to worse, they can go into the Secret Info Locker that will withstand a direct hit from a meteor.
Seriously, they and all the folks in the potential strike area are in our prayers. The ARES and MARS chatter is picking up. I-10 looks like a potential disaster.
http://www.nhc.noaa.gov/refresh/graphics_at2+shtml/204602.shtml?hwind120?large
Thanks for the well wishes ... looks like we will escape most, if not all of the 'big blow.' I'm just hoping that the Mississippi isn't back washed too far north from the Gulf. Just made a trip over there to check on the progress of a new plant we're building. Unfortunately it sit's just off the river with water access to the gulf.
I agree with most of your conclusions. The need for capital has been ther crippling blow for CYGX from the beginning. That is one of the reasons several of us have called for getting someone with the right resume and rolodex to handle funding and being able to plan for capital needs and then having that capital on hand.
It is sad that some fabulous scientific minds have been handicapped by never having anywhere near close to enough money to progress their research and discoveries. It sometimes seems that the science of the day has to be the cheapest one at that moment. We shareholders have paid the price for incompetence in the CFO office. Maybe we just need to vote another few dozen million share options and all of our problems would go away.
Reread what I said:
How far has CYGX stock fallen since Malcolm took over? If it will make it easier, for you, it was around $3.00 per share back a few months after he arrived as Top Dog.
It was on a climb when Malcolm took over and continued for another couple of months. Then it went into freefall and has never recovered. Pull up a ten year chart. I think it hit $3.00+ during the winter of 1999-2000, but will have to re-check it out.
Back then the herpes treatment was getting the red-carpet reception like the syn DNA is now.
ROFL ... 'hook 'em horns' is the battle cry of the University of Texas Longhorns ... it is anathma to Aggies (Texas A&M) and Red Raiders (Texas Tech) ... Have several friends who are of the Illini Ilk (or is it Elk) ... LOL LOL
I'm on the western outskirts of Houston. We are having one heck of a blow here right now. The radar is showing three cascading lines of squals moving our direction, so I may shut down at any moment. My Aggie kid just called and said that they had lost the lights at a pool hall a couple of miles north of our home. A couple of the emergency communications groups have been activated. MARS hasn't yet, so I can stay home and enjoy the thunder ...LOLOL
WOW, that was close ... about 1500 - 2000 meters ... my ears are still ringing ...
We have friends and family in NOL and are holding our breath for them. The current track is defying earlier predictions. I am just waiting for the ninety degree turn to Starboard ...
My little sis just transfered to nights at Scott and White ... seems like it is a lot quieter and fewer stats than in the daytime. Is it the same with you?
BTW, I wonder why nobody will discuss past performances and everyone just wants to keep saying syn DNA ... how many discoveries and courses does this make that were supposed to be our salvation? Unless we get proper financing, Yin and the brilliant back-shop gang are going to be denied their waltz across the stage in Helsinki. Agree?
Wow, just wait till my Raiders get those horns in sight ... LOLOL ... we are having one h&ll of a storm developing here.
The price at which I purchased stock is no more your business than your sexual orientation is mine.
Why are you acting like that poor freezing wet little puppy and refusing to address the value of the stock (both pps and equity) and where Malcolm's vast education and academic credentials have taken it today ... with the assistance of his financial guru, LW, of course.
No, you just have to ANSWER the question. Why are you acting like a terrified little wet puppy and avoiding a direct question? In case you have forgotten, here it is rephrased again:
How far has CYGX stock fallen since Malcolm took over? If it will make it easier, for you, it was around $3.00 per share back a few months after he arrived as Top Dog.
Instead of trying to stick your nose into my business where it doesn't belong, just answer the question:
Hogger wrote:
Uh, and BTW, just how much has CYGX dropped since Malcolm took over? Until you answer that, you are relegated to the cloakroom wearing a dunce hat.
GDEPC had written
Quoth gdepc: "you can make fun but when I asked hc to provide his top secret anti cygx info he bailed
If I am wrong and I must of have missed hc post
where is this info that will blow the lid off of cygx
Sorry, gdepc, Happy didn't bail. He just finds you so amusing ... you know, you're the type that brings more comic relief than a liter of Guiness. I certainly am able to laugh at your attempts to play the little role you are playing. Unfortunately, you must admit, you play it rather poorly.
He might not want to tell you any of the top secret stuff that is so hot that it must be compartmentalized and you just don't belong in the compartment. Sorry, you haven't earned your clearance for that kind of info, junior.
Uh, and BTW, just how much has CYGX dropped since Malcolm took over? Until you answer that, you are relegated to the cloakroom wearing a dunce hat.
Quoth gdepc: "you can make fun but when I asked hc to provide his top secret anti cygx info he bailed
If I am wrong and I must of have missed hc post
where is this info that will blow the lid off of cygx
Pleeeze Happy, say it ain't so and thet youse is jist kiddin ... ya mean them thar midnight swearin's and olth takin was jist kiddin around ... if thair ain't no sekret infurmatiun, then why did we have to hold them burnin papers in our hands and swear not to difulge thair kontents? Huh ... tell me thet. And who was that masked lawyer feller?
Oh, and I lewft youse a sekret messige in the tree stump akross the street frum the Generel JEB Stuart stachew. Itz ritten in the sekret code where you referse the letters ... u know a equal z and b equals y and so-on-an-so-forth. Jist dont let geedeepac know how to cipher it.
darn you figured out my "secret info gig" (and called me to task to boot). Golly geez, I feel so much better since you outed me. It was all a lie and I was just doing a little tree shaking. And Neo does not know anything you would want to know. All is well in cytogenixland . .
roflmao@gdepc ... if you are capable of following a trend, then take it up with your alter-ego paulNESS ... he started it ...
Hello thaliowizard ,I see your command of the English language is still lacking , I hear China is having a problem with overly prescribing antibiotic and the resistant bacteria is overwhelming your people , Cytogenix has the cure, and the bacteria can never get resistant to it .
Now, are you afraid to address the falling PPS? Have you got a link to that independant verification of the "cure?"
You may think you're pretty clever, but you, PN and a couple of others are so deep in the dark that you are in need of light being piped in so you can see the obvious.
My, My ... we would love to see just one iota of proof of that posted and verified ... that bit of news might actually get us back about $ 0.40 per share.
Cytogenix has the cure, and the bacteria can never get resistant to it .
BTW, have you suggested that the "select few" at CYGX get another 18 million options ... I seem to recall how greatly you and a few of the others were claiming it would help the PPS.
And if you are going to again make light of someones command of the English language, you might try talking into a tape recorder and playing it back to yourself and even proof-reading your posts and ... well, heck, you might even question where gdpec learned his English. Or, are you going to launch another little attack on people of the Asian persuasion?
Guang Long (Hoggers Chinese given name)
Good grief gdepc, obviously you have never gone to China. If I get to the Houston consulate early enough in the day, I can pick up my visa that afternoon ... longest it has ever taken is until the next morning.
if you were going to China It would take some time to get permission from china to enter
gdpec, I believe our technology is better and has several advantages. Of course, my worry is that we will not have the funding to get ours to market early enough to become dominant.
The greatest obstacle I can see to Yin and the back-shop gang waltzing across the stage at Helsinki is simple --- funding.
BTW, have we had an SEC filing on time since Maury left?
Here's another application where we are going to get left behind if we don't have enough money to properly fund Yin and the back shop gang's work. BTW, I just had to get the five deuces post ... lol
Friday, August 12, 2005
By Daniel J. DeNoon
A small human study may point the way to a cure for AIDS.
Behind the stunning results is a totally new approach to HIV treatment. It makes use of an epilepsy drug -- valproic acid -- that flushes HIV out of its most remote hiding places in the body.
Combined with powerful HIV drugs, the approach might totally eliminate the AIDS virus from the body. That promises a cure for AIDS, says study leader David M. Margolis, MD.
"This might lead to a therapy that would clear virus from an infected person, or reduce it to such a low level they would not need treatment for a very long time," Margolis tells WebMD. "But that is only a hope for the future. It will require a lot more work. Today, HIV is still a problem."
The Margolis team's groundbreaking report appears in the Aug. 13 issue of The Lancet. Accompanying it is an editorial by McGill University researcher Jean-Pierre Routy, MD, PhD.
"This is very serious data -- a very exciting piece of information," Routy tells WebMD. "For the first time, the disease may be attacked in the last cells where it is hiding. That is a sign of hope. We can expect one day to remove all these infected cells."
Read WebMD's "Statins May Help Curb Spread of HIV in Body"
HIV in Hiding
A decade ago, there was great optimism that powerful AIDS drug combinations would eliminate HIV from the bodies of infected people. These highly active antiretroviral therapies -- HAART -- put the AIDS virus on the defensive. The drugs kept HIV levels so low, it was hoped that the virus would soon vanish from the body.
That didn't happen. The reason: latent HIV. Latent HIV is inactive virus planted deep in the DNA of human cells. There it lies in wait, beyond the reach of anti-HIV drugs. This tiny, smoldering infection is enough to burst into full-fledged AIDS once a person stops taking HAART.
Researchers have tried everything, from years of toxic drugs to bone marrow transplants, to get rid of latent HIV. None of it worked. Making this even more maddening were recent findings that this last reservoir of HIV infection is very small.
"The total amount of infected cells is very small: just 1 gram in a person with normal body weight," Routy says. "But until a few weeks ago it was impossible to attack these cells."
Read WebMD's "Study: Many in U.S. Misunderstand HIV Vaccine"
Unmasking HIV
What changed? Until now, most efforts focused on turning the latent infection into active infection. The idea was to get HIV out in the open where HAART drugs and immune responses could get at it. But these approaches had the disadvantage of making HIV replicate faster throughout the body.
Margolis' team was one of several taking a different approach. Instead of activating the HIV gene in latent cells, they changed the cells' DNA architecture. To do this, they took advantage of the ability of valproic acid to inhibit an enzyme called HDAC.
"We thought a way to unmask latent virus would be to inhibit HDAC so you are not activating the virus but sort of taking the brake off," Margolis says.
Read WebMD's "More Than 1 Million Americans Living With HIV"
Patients Respond
It worked in the test tube. So Margolis and colleagues tested their idea at the University of Texas Southwest Medical Center in Dallas.
They recruited four volunteers with HIV infection. Each of them once had AIDS, but had their virus brought under control by HAART drugs. However, none of these volunteers had immune responses capable of fighting HIV.
Margolis and colleagues first intensified the patients' treatment by adding a new kind of HIV drug, Fuseon, to their treatment regimens. Then they gave them valproic acid for three months.
The results were unprecedented. Three of the four volunteers had an average 75 percent decrease in their latent HIV pool.
That's pretty amazing -- but none of the patients were actually cured of HIV infection. Margolis says it's going to take time to learn the best way to use valproic acid as an anti-HIV drug. And even if it's 100 percent effective at eliminating latent virus, he notes that current HAART treatment does not totally eliminate HIV replication. Until that happens, the pool of latent virus could always be replenished.
But that isn't always going to be an obstacle, Margolis predicts.
"If I look backward five to 10 years to the relative impotency of treatment, and look forward to how simple and effective treatment might be in five or 10 years, you will see the field does a good job of inhibiting HIV," he says. "If that is the only problem to overcome, we can definitely cure infection."
Read WebMD's "U.S. HIV-Infected Youth Take More Risks"
Warning to Patients: Don't Try This at Home
Margolis warns patients not to try taking valproic acid. It's a drug with serious possible side effects that include liver damage and, if taken by pregnant women, birth defects. Valproic acid also has dangerous interactions with AIDS drugs. In fact, one of the four patients in the study developed serious anemia because of an interaction with one of the drugs in his HAART regimen.
"It is totally irrational for patients to add valproic acid to therapy, outside clinical trials, at this point," Margolis says. "How much valproic acid would they take? How long would they take it for? How could you measure when they had enough? How do they know when to stop? There are plenty of reasons not to take valproic acid at this point."
Routy says that his team is organizing a clinical trial to try to find the best way to use valproic acid as an adjunct to HAART. He also expects the findings to give new impetus to therapeutic AIDS vaccines.
Meanwhile, the world AIDS pandemic continues unabated.
"We have to focus on HIV treatment today," Margolis says. "Right now we must continue to prevent, detect, and treat HIV infection. Finding a vaccine to prevent AIDS is still very important. But that goal is no more challenging than the goal of eradicating infection. And that is a worthy goal as well."
"Eradicating HIV from the body is a big hope," Routy. "But the hope is not today."
By Daniel J. DeNoon, reviewed by Brunilda Nazario, MD
SOURCES: Lehrman, G. The Lancet, Aug. 13, 2005; vol 366: pp 549-555. Routy, J.-P. The Lancet, Aug. 13, 2005; vol 366: pp 523-524. David M. Margolis, MD, professor of medicine, microbiology and public health, University of North Carolina, Chapel Hill. Jean-Pierre Routy, MD, PhD, associate professor, division of hematology, McGill University, Montreal.