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The trial didn't even started yet!
Nobody wants to sign the deal yet unless they see some positive data with NEO IMO!
I don't expect anything surprise until march 2019!
[$$] Cellular Biomedicine, Novartis in CAR-T Cell Therapy Pact
seems the chinese is getting more attentions from BP
https://finance.yahoo.com/m/ad55d252-8d08-35c0-a858-a4e6bcb6741c/%5B%24%24%5D-cellular-biomedicine%2C.html
New updated website leadership
https://www.advaxis.com/about-us/?pagelink=leadership
Alexion (ALXN) to Acquire Biotech Syntimmune for $1.2 Billion
Good news! This is why most Neoantigen companies are up today
https://finance.yahoo.com/news/alexion-alxn-acquire-biotech-syntimmune-143802663.html
The problem with this company is every time new management team came on board, they make some changes but never get things done on time!
I have to say Idiot BOD hire Idiot management team. dump people always dump!
Anavex Life Sciences to Present at the 2018 Cantor Fitzgerald Global Healthcare Conference
They also Live webcast, so no big deal with webcast Advaxis. Don't speculate too much about it.
https://finance.yahoo.com/news/anavex-life-sciences-present-2018-110000383.html
President and Chief Executive Officer of Advaxis, will present a corporate overview at the Cantor Fitzgerald Global Healthcare Conference on Monday, October 1, 2018 at 9:30 a.m. Eastern time.
Agree, it is just a regular investor conference, don't speculate anything special. For the last two years, advaxis only delivered negative news during most conference all. so let's just hope we don't get negative news! One bad news we could expect is Ken will offical announce the end of AXAL trial. That we know already from previous CC. we had enough all this kind of CC!
The number one important for advaxis right now is good positive data, this is the only thing could take care the share price and cash issue. good data could lead more investment from big BPs and good deals.also stock price could reach to a fair value. AMRN is a great example what the market wants to see.
Focus: As China builds biotech sector, cash floods U.S. startups
Ken needs to pay some attention to china, chinese got the money!
https://finance.yahoo.com/news/focus-china-builds-biotech-sector-042629387.html
AXALis done IMO. advaxis has no money to support this anymore. They just dont'want to have a CC to PR it.
You get what you pay for! Advaxis has no money to hire a CEO from top BP.
batermere, buy 10K shares for $8K now, or buy 10K for $80K later. Make your own decision.
i dont think they want to reverse 70million shares to 7 million shares right now.
how many outstanding shares advaxis has now?
Historical low share price, PSA data first QT 2019, NEO data first half 2019 and more data throu 2019. No hurt to pick up some shares at this moment IMO.
AXAL is out IMO. Too much money wasted on this old science.
Investors Cash Out of Biotech ETF as M&A Boom Never Materializes
https://www.bloomberg.com/news/articles/2018-09-17/investors-cash-out-of-biotech-etf-as-m-a-boom-never-materializes
CEO and CFO are on the right track, the most important is trial data, without a good positive data, the company is not going to surive.no matter how many trials or partners they have.good positive could lead advaxis to many good deals IMO. AXAL is history, spend too much on that. lets stop it and move on.NEO and HOT are the future. all we need is good data,data,data!!!
If they have a big deals and good data coming soon, share price will take care itself, i don't see reverse split. remember outstanding shares still not that much.
All I did last week was buy buy buy, don't ask me why.
Here are my thoughts: Ken reached Amgen, Amgen said go fxxk yourself, we have NEO that covers everything, we don't need HOT. so no money from AMGEN. Then KEN reached Merck, BMY, ASTRA, and told no money until we see some positive result from NEO and HOT.
So Ken got fxxked and didn't get any deals and money. Here is the dilution we been waiting for!
Conclusion: Either we have good science and later get bought out, or our science is bull$hit and this is totally scam, and file bankrupcy at end just like He did with Rossett!
This is JMHO
Buy or Sell?
Well Ken did again!
aduro doing very well recently, why?
looks like Dan nailed another $15 million dollars for ONCS today
https://finance.yahoo.com/news/oncosec-announces-15-million-market-113000006.html
Got give credit to Ken this one, making a dead one alive again!
why yahoo dont' show the news?
this news is just appetizar, more to come. os therapedic ceo from johnson&johnson and amgen. very interesting.
September presentation is up, any changes?
https://www.advaxis.com/wp-content/uploads/2018/08/Corporate-Presentation-September-2018.pdf
S3 Barometer
16 Nov 2012 | 00:50 GMT | Posted by Adam Bristol | Category: Finance
Access to capital is essential for development-stage biotechs, yet the capital markets for public and private biotech companies are notoriously fragile. For private companies, venture investing in the life sciences has recovered from a rough patch in the ’08-’09 span to the robust financing environment in last year and a half. In the public markets, IPOs haven’t fully rebounded to historical levels, but follow-on financings and debt deals have been brisk as the biotech sector has performed extraordinarily well in 2012. Indeed, the NASDQ biotech index is up ~35% YTD at the end of the third quarter.
Public biotech companies have a mechanism, a shelf registration statement (or S-3, as it is known in SEC terminology), to register securities in advance of their issuance. The securities are “put on the shelf,” generally speaking, allowing them to be sold at any point within the 3-year lifespan of the shelf registration statement. One would think that having an active shelf registration on file is a must-half for public biotechs; they exist in a topsy-turvy macroeconomic environment compounded by the highs and lows of product development. Allowing them to raise money opportunistically and take advantage of strong capital markets or simply strong interest in their stock should be a good thing.
However, this is not the typical view. The filing of a shelf registration statement is often met with derision, and considered a bad omen that shareholder dilution is around the corner. If you follow any of the biotech stock watchers on Twitter, you know what I mean. My sense is that complaints arise primarily for three reasons:
Investors seek to avoid dilution, and the issuance of new shares via draw downs from a shelf dilutes existing shareholders.
Filing of an S-3 shelf registration signals to the market that a financing is forthcoming, thus creating an overhang on the stock, depressing its performance. In other words, why should big institutions buy shares in the open market if they can simply wait and buy in an upcoming follow-on financing?
An active shelf is like a credit line for management that can be tapped at their discretion, so incentives are not fully aligned with shareholders if shelves are utilized haphazardly.
I don’t like dilution either, and I don’t like the artificial feel to the market cap increases that result from the issuance of more shares. But is there empirical support to the notion that S-3 filings predict subsequent financings? Is filing an S-3 a reflection of management and corporate strategy or a fact of life for R&D stage biotechs?
To address these questions, I looked at new shelf registration statements filed between Q2 2008 and Q2 2012 by US-based small cap biotech companies devoted to new drug discovery and drug development. I defined “small cap” as less than $1 billion, as this captures the vast majority of pre-commercial companies. I restricted the list to drug discovery and development companies because a) their value is largely “technology value” — the value ascribed to their development programs above the cash balance, and b) their cost of capital is heavily influenced by the perceived value of their technology.
During this period, I tallied 269 new shelf registration statements by 180 companies (some companies filed more than one, a replacement to an existing shelf that was either depleted or not). By my calculation, there are approximately 340 US-listed, small cap drug development companies in the sub-$1 billion range, so around 50% of these utilize shelf registration statements. Filing S-3s are not a universal capital-raising strategy.
But S-3 filers are a diverse group, with market caps at filing of between $11 million and $840 million. Further, the size of the shelf (that is, the total amount of capital that can be raised by the securities contained in the shelf) varied as well, though there was a slight trend for larger market cap companies to file larger S-3s. Of course, shareholders are interested in “implied dilution,” or the dilution that would occur if the entire shelf was drawn down. As expected, the implied dilution, or the ratio of the shelf size to market cap at filing, tends to be larger for small companies, but as shown in the figure (click to enlarge), there are some significant outliers. I assume that shelf size is related to the cost-intensiveness of future development plans, but perhaps I’m giving management too much credit.
Is an S-3 filing a harbinger of a near-term financing? The data say: Yes. Of the 269 shelves, 207 (77%) have raised money. Of those 244 S-3s filed before January 1, 2012, that number rises to 82% (199 of 244). If one excludes those companies that were acquired with an active shelf in place (e.g., ISTA, ANDS, INHX, CLDA, ISPH, ADLR, MITI, PRX, PPCO), the number is closer to 85%.
The average time to the first financing was 207 days, with a median of 240 days. The magnitude of the first drawdown covered the full range, from 1% of the shelf to the full 100%. As shown in the figure, the majority of the first financings raised 50% or less of the full shelf value.
Taken together, the data around S-3s in recent years, a period of economic hardship, indicate that:
Only about half of small cap therapeutics companies file shelf registrations
For those that do, the overwhelming majority utilize them, usually in about 6 months
The first drawn down is usually 50% of the shelf or less, which could give shareholders an estimate of the extent of dilution at a first raise.
Of course, as I noted above, raising money is a necessity for biotech, so noting here that they do, via the shelf mechanism, is somewhat self-evident; if a company files a shelf, why not use it? More important is when and how. Ideally, shelves are utilized at opportunities when share price is high. Remember that S-3 remain active for three years, so market cap at the time of shelf drawn downs is perhaps a more important metric than market cap at the time of filing. If share price rises (and so market cap) during that time, the implied dilution would decrease. These are questions to explore in future posts.
I should note that, in the process of compiling these data, I put together a fairly extensive spreadsheet with numerous metrics related to S-3 filers, such as stock performance, extent of insider holdings, estimated runway at the time of filing/draw-down, share price at first raise, etc. If any readers are interested in a particular question, please let me know in the comments below or via direct message on Twitter and I’ll see if I can address it with my database.
Aduro is $7.00 now! I'm praying KEN not going to kill us with bad news!
September CC: we will know if AXAL find a partner or will be shelved, that's what Kenneth said in the last CC. I really don't expect anything spectacular at this moment.
I dont' think we will hear any HOT deals in the CC, i think it will be after CC.
Also we may hear raising money again with more shared issued.
Possible Amgen payment, we will see!
More executive left Amgen, Laura Hamill switches from Amgen to Gilead
https://www.thepharmaletter.com/article/laura-hamill-switches-from-amgen-to-gilead
I had a nightmare last night about advaxis news! fxck! the dream news was ken didn't create any deals, he did dilution instead, the stock crashed. What a bad dream! also i lost my wallet too in the dream! I hope my dream not coming true.
Amgen missed KITE, this time they will not let that happen with advaxis!
Rmarc, you are too late, it was there this morning, they removed later!