Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
I wrote Nader a longer email. I don't expect any answer. I pointed strongly out that it is a severe mistake that he didn't apply for EUA for M&M and now for S&C. If you always obey you just get more kicks in your butt. Very weak performance. You need not only to be smart, you need also balls.
Great action. Better than any blabla - like from me.
What is that "mercy"? Only money counts. Woodcock doesnt need to have mercy, she should decide in interst of people's life.
I wrote this journalist 1 week ago a email with our k8 enclosed. Except an automated answer I didn't get any reply. It seems that they are not interested. Do investigative journalists still exist? I thought these dinosaurs died Million years ago. Today only sh.t mainstream media are consumed by our "Mickley Mouse Society".
I get on board as a sponsor. But what is about FDA who is infact the biggest cheater on earth in this game?
Assumption Standard Care Average Mortality 30%
total Death 90
Reduction Mortality for Critical 24%
Mortality Placebo Severe 28%
Mortality Placebo for Critical 80%
LL Placebo LL Placebo
all 384 67% 33% Death 20% 30%
all 384 257 127 Death 52 38 90
critical 62 41,54 20,46 61% 80%
critical 16% 16% 16% 25 16 42
Severe 84% 84% 84% 9% 28%
Severe 322 216 106 19 30 48
44 46 90
20% 36%
Unfortunately, the Excel Paste doesn't work very well but I recalculated for Mortality for LL for SEVERE: 9%
After reading the results, I was disappointed as I hoped, based on my calculation with the 50% data, to see a 40% reduction in mortality.
I was thinking too complicated, but a long walk cleared my mind, and I see now the situation is simple and straight, very positive. Best illustrated by the following example:
Assumptions:
1) mortality with Standard Care when one is in the critical phase (one called the phase on the "bed of death") is, let's say, 60%
2) for the sake of simple calculation, let's say 100 people in the hospital in critical condition.
3)When my father died, he was in ICU for a different reason, cardiovascular matters. I had with the doctor a discussion of what to expect. Now let's assume he got a second life and is unfortunately in hospital but this time because of Covid and he is again in very critical condition.
Now the doctor asks me, should we treat your father with Leronlimab? I don't know anything about Leronlimab and Statistical Relevance, but my doctor explains to me:
1) we have currently 100 patients here in the same condition as your father.
2) only 40 of these 100 people will survive; 60 will die. Your father might be among them.
3) if I give him LL like I will give now the others, 54 instead of 40 will survive, and he will less likely become a long hauler.
4) But when we give your father Leronlimab like the others, we are going to keep 14,4 People more alive
5) I ask, what is the risk of another severe health damage when you treat him with LL?
6) Doctor says "zero risks" for adverse effects.
7) I ask then: AND WHY DO YOU ASK ME WHEN HIS CHANCE BECOMES MUCH BETTER?
8) Doctors answers because it is not FDA approved, and the results were not statistically significant! But 24% reduction in mortality it showed.
9) I say right away: "I give a sh.t on statistical significance."
If the FDA let people die, although LL showed a 24% reduction in mortality for those on the "death bed" and the medicine has no adverse effects, the FDA needs to be sued from today onward for murder on each death.
That simple it is!
Thank you
Further to my previous 2 posts:
1) getting sick on Covid taking the treatment with LL is a nobrainer for everyone. 24% better chance without risk. Maybe no non- hauler risk. The best timing needs to be defined.
2) severe arms results are unknown. Considering results of treatments early last year in Montefiore hospital the results comparing with placebo arms should be much better. But why not published?? If results great we are winners and get EUA, if not, I believe FDA will satisfy BP in the following way:
3) we continue the trial to get much more patients enrolled for 42 and 60 days.
4) FDA will keep us in the waiting loop for another 3 months without any kind of further approvals.
5) this keep us in check for another 3 months and give BP another time to be successful.
6) FDA has covered it's a.. as no denial but just wait to be more sure.
7) no FDA means no other country will go ahead. The world is governed by corrupted beaucrats.
8) Monday we will know 100% our near term destiny
Further to my previous post:
For me it would be of highly interesting how many patients change from critical to severe for both arms. Such figure would support my view mentioned in my previous post.
Another interesting analysis would be to know the percentage of the longhaulers coming from each group (M&M, critical...). Also here one could recalculate the impact of LL. In my opinion this is anyway a "Must Be Done" homework before recruiting patients for LH study. I need to know what damage has been generated, not only which one.
Without homework the LH trail will generate a missed endpoint.
For me the whole story is discussed in the very wrong and narrow way.
Facts:
1) very good on NEWS2
2) very good on critical
Consequence for me for the total picture:
1) better in NEWS2 means less mild & moderate
2) less in M&M means less critical
3) less critical means less severe
4) 24% less deaths on critical
5) less longhaulers as less in any status above M&M
If we see the change in this pyramid than we wouldn't discuss on 24%. The whole benefit is incredible much more better.
Will we have any discussion on this chain of reaction? I guess not. Would be a great task for a good statisican.
I watched today for 1/2 hour level 2 trading. The unbelievable manipulative pattern of the criminal gang, called MM, is visible after 10 minutes, even for a greenhorn like me.
Do all these guys shaving in the morning without mirror?
If you want to buy today in this tight market 1 mio shares, you will end up to pay for the last shares already 10$. Good luck for those who in need of shares. Time is over.
Great information. Thank you!
Any idea why Nader never published the enrollment of the first patient or similar?
I am convinced the results of CD12 are great. I expect 40% reduction of mortality.
I understand that FDA stopped recently many trials which failed terribly while our drug are after unblinding is still in use.
Do we have not a longterm experienced expert on this board who knows what this "confidential whispering means"? Negative results should be already out if any. 2 months after end of the trial the mortality is known. What does this mean? Is FDA trying to spin for us other obstacles to delay us again without EUA?
Come on, why such a post? We all have seen in the last few weeks that FDA stopped several trials from well-known companies. Does anyone really believe that FDA would hesitate to send CYDY to hell if the results would be bad?
Here is my view and it would be interesting to get the opinion from practitioners:
Question: If one takes LL against e.g. lung cancer and LL works for 18 other cancers as well, is he/she at this time also protected against Covid, HIV and the other 18 types of cancer as well?
Others:
1)Manufacturing and logistics are much simpler and cheaper for a drug that works for 20 different indications than for 20 different drugs which work only for one indication
2)Such a drug is killing BP and in a buyout too expensive and these are the reasons why CYDY has so many and strong enemies.
Volume is totally drying up. Everybody is waiting and holding his cards.
Vaccines don't hurt therapies business. If you say like this, it is just proof that you have no understanding of vaccines and therapies.
How is such an affront against BP company possible? They got a huge amount of money and can't deliver now? What has changed?
What doesn't make sense to us or not doesn't matter, what matters is what is written until corrected.
Therefore, I asked Rockleo to give us his interpretation as he is using LL in his hospital. He will know what matters and how to read this sentence.
Rockleo,
please be so kind and comment on the following quotes:
1) your quote:
If data was bad..FDA would close down the EIND’s and OLE ..Right away..!!!
2) quote from a previous press release:
"Treatment of qualified patients will continue until the trial’s data is unblinded."
Does this mean that people again start to die as no EIND application is now for the next 2 weeks possible? Or has FDA released a new permit? You are a practical doctor using LL. Are you now continuing or have you stopped today?
Guys, what do you expect? We have 394 complex data sets. It took them 6 weeks to sort these data out and make them reliable a clean. Now data can't be changed anymore.
We have many important endpoints, and of course, mortality is the most important one. But looking into these data, making the right conclusions, discussing them and coming to decisions with such an important impact will take 2 weeks. Whether we like it or not, we are not the only ones who want to talk with them.
FDA has been, in my opinion, not our friend, but now they need to cover their a.. why we have been on hold for 1o months.
The data are, in my opinion, excellent. As I wrote some time ago, I expect a 40 to 50% reduction in mortality. Will this result in approve? The game we know- its about money and not life!
50 days ago the hottest spot for LL success was the Philippines. And now we don't talk anymore with them? Was the Philippines just to entertain us?
From Yahoo; very interesting!
Mass obduction in Hamburg hospital
What causes covid 19 deaths
Hamburg forensic pathologists performed autopsies on more than 600 Covid-19 deaths to understand the course and cause of death. They found out what people with severe courses die of and what can prevent death in some cases.
Most Covid 19 patients with a severe course die from the viral infection due to pre-existing conditions and because of their advanced age. This is the result of an evaluation by the Institute of Forensic Medicine at the University Medical Center Hamburg-Eppendorf (UKE). The physicians performed 735 autopsies last year. Of these, 618 died from Covid-19. In seven percent, however, another cause was responsible for the death, they said.
Overall, 88 percent of those who died from Covid-19 had at least three to four pre-existing conditions, he said, and the vast majority of all deaths were older than 76. Some deaths with the new Covid-19 mutations have also been autopsied, UKE scientists said. However, the causes of death were the same as with the conventional virus variant.
But the forensic scientists also had some good news: the number of Covid-19 deaths from pulmonary embolism has dropped noticeably. "Among the first hundred deaths in the spring of last year, more than half still died from pulmonary embolisms," said forensic pathologist Benjamin Ondruschka when asked by SPIEGEL. In the meantime, he said, the number has declined noticeably.
The chances of survival for seriously ill Covid 19 patients could be increased by anticoagulants. This was also confirmed by the autopsy of the more than 600 cases, Ondruschka said. The anticoagulants - or blood thinners - reduce thrombosis and pulmonary embolism. As the study of the deceased showed, life was prolonged by the blood thinners, yet the patients could not always be saved.
Already in May, researchers at the UKE had warned that blood clotting often becomes extremely unbalanced due to Sars-CoV-2. In many Covid-19 patients, the blood clots, they said at the time.
The German Society for Thrombosis and Hemostasis Research also recommended at the time that every hospitalized patient be treated with the drug heparin in high doses, unless there was something to the contrary.
"The anticoagulants help, but cannot prevent fatal pulmonary embolisms in every case," said study author Ondruschka. Nevertheless, he said, physicians have had a "learning curve" since the first wave a year ago. "We have reduced the absolute number of thromboses and prolonged the phase of survival for the final deceased," the forensic physician said at the presentation of the study in Hamburg.
Causes of death: Age, pre-existing conditions and obesity
Most corona patients with severe courses die of multiple organ failure or sepsis in addition to pulmonary emboli.
Often, these causes of death are favored by a number of pre-existing conditions, which are particularly prevalent in people of advanced age, the UKE scientists said. People with severe courses usually suffered from high blood pressure, renal insufficiency, diabetes, tumors or chronic obstructive pulmonary disease (COPD). Only one percent of those who died had no previous illness - here, more detailed research is needed into the causes.
An unhealthy lifestyle is often an aggravating factor: 20 percent of those who died were morbidly overweight, he said. "Obesity is a decisive factor in severe courses," Ondruschka said.
The youngest Corona deceased autopsied by medical examiners was 29 years old, he said, and the oldest deceased was 100. Seven people died as a result of the infection before reaching the age of 50. The men who died were statistically slightly younger than the women, and more men died than women. Children or adolescents were not among the deaths studied.
Only one effective drug
Despite intensive research, there are still too few effective drugs against covid-19, says Stefan Kluge, head of the hospital's intensive care clinic. "Dexamethasone is the only drug that has been shown to reduce mortality," Kluge says. With remdesivir, on the other hand, high hopes would have been disappointed. "Large studies have shown that remdesivir has little effect on severely ill patients," Kluge said.
Currently, 400 drugs are being studied worldwide, but there are also extremely many setbacks, he said. "We know, for example, that vitamin D does not protect against severe courses, despite all the announcements," Kluge said.
sug/dpa
Thank you so much. Your guidance very much appreciate. Finally I know it is time to sell my 100 000 shares.
Have you also sold already?
We are playing in a game for which the rules are adopted by FDA as needed to please BP. They dont like LL and lifes they dont care. I am here for almost 5 years. I expect, reading the figures, a 40% reduction of mortality by LL. Will we get an approval for the CD12 results when they are as fantastic as I expect? If not, then also for HIV we will never get an approval or maybe in 2030. The agenda is very clear and has only one topic: money for BP friends.
It honors you that you believe in ethics. Real world is only about making money by drugs. Leronlimab is real medicine to save countless people's life.
LL makes money for 50000 retail investors and not just for ONE pharma company. Big Pharma is angry about the fact that NP didint give LL as a cheap gift.
I dont need the virus to get sick. I just need to listen to the recent interview of JW. No way that she will admit that she promoted and approved during her time with OWS mostly ineffective therapeutic drugs to fight Covid.
Regeneron was approved due to hype generated by Fauci and FDA. In her interview she tells it like it was a success. The whole strategy she run over months with her approval process was deadly wrong.
In my opinion, Woodcock is a part of the BP-Mauci- gang. She had many months to prove otherwise- she didn't. Why she should it do now? If it depends on her, I think we will never get any kind of approval. Does it matter how many unnecessary deaths we got and we will continue to have? If one lacks ethics then you can do any crime. I hope there are other decision-makers in the FDA than her. She has gone so far, she will not return. You would do better to send emails to God than to her! He might have mercy with us.
Woodcock made it very clear in an interview many months ago that she likes BP as small pharma are just incapable to bring something to an end. She should know that the BP prevent small pharma to succeed so they can buy them cheaply. And she is collaborating with BP by thinking like this.
FDA should be on the side of sick people and bring promising medicine as quick as possible to the market.
Bravo!
Now BP- lover Woodcock needs finally to decide. Another unnecessary 100 000 deaths more and continue in bed with BP or approval of LL.
To put all expectations for the release of CD12 results into a perspective of real-world, I reviewed the last relevant press releases:
1) 25.8. The Press release that 195 patients were enrolled
2) 20.10. The Press release that DSMC recommended the continuation of the trial without changes.
In short, it took for the first 150 patients 2 months to get a decision of DSMC. What could we expect for the second 150 patients? It could be faster of course as the evaluations could be definitely quicker. It could be even very fast, but who is in a hurry except for CYDY? Not AMARAC, not FDA, only those who are in Emergency Rooms and seeing the death into its eyes! And of course, the doctors who are fighting for their patient's lives. But who cares?
So we can assume that results might come up not earlier than within 1 month after the 28 days completed (12.1.21), rather 6 weeks and then another 2 weeks for FDA, precondition CYDY doesn't forget to apply for EUA.
Get your expectations down and don't expect anything before 15.2. (Monday) or better 22.2. (Monday). FDA decision rather 15.3. (Monday).
We will need to have a lot of patience. The share price will continue to erode as I don't expect Nader to up-list to NASDAQ before 15.2. All other news, except the Philippines, will not matter.
I will be happy if you know it better and it will be faster, but I will not wait another 3 weeks day by day with the frustration because I have the wrong expectations.
OWS is dead. It was a money destroying machine in favor of BP. One crocked organisation less. FDA, OWS, BP ALL all are one gang. People move from one place to the other, like Janet, but stay within the clan.
This statistic is a typical example of how you can manipulate people. In fact, it says nothing. Absolutely nothing. These guys have either no clue about what they are talking or simply intentionally manipulators.
Mr Fauci is a man of principles and honour! If he declares today that he is happy and has the pleasure to announce that the USA is again joining WHO; shouldn't he have resigned when Trump declared USA quits their membership?
This type of turning neck men turning their head according to how the wind blows. This type of human species is surviving in every political environment.
Long live Mr Fauci, CYDY's best friend.
How can shorties cover their 25 to 30 Mio shares with 1 to 2 Mio shares turnover per day? Any day now the Philippines can come in; Any day now positive results will be reported.