I wish I would have bought this yesterday. Holy cow.

What is the current float? Interested in locking up some shares.

I could be wrong but it appears to only be
mobile surveillance. It doesn't have capability to apprehend/stun a
perpetrator or to stop an assault, for example. Drones have a much larger
field of view and don't have to worry about obstacles. Granted, drones
need an operator. This also needs someone to view the video that this
thing shoots in real time and then needs to act in order to prevent
anything that might be going down. What is it that makes you all think this
will move up?

Wish I would have waited.

I'm in. Got some at .006 - Lets go to .025!

The Republican candidate who is running to replace Jeff Sessions senate seat, Mo Brooks, is embracing legal medical cannabis. It's happening.

Getting ready for liftoff

Good news usually on Tues or Wed. morning

Exactly right. That's what I do too.

Yeah I totally agree. The upside here is tremendous. The recent selling has been mostly triggered stop-losses and irrational sells below .50-.55. Some people don't have any patience. Remember, never set a stop-loss on a volatile stock unless you want your shares stolen.

DEA could reschedule sooner than we think...

Disclaimer: I am loading up on US weed stocks right now

I think it happens in the next 6 months. I think it happens this fast because:

Epidiolex has been waiting for approval since March 14/16 and enough clinical trials have been past that approval is inevitable (last year the FDA gave its recommendation on scheduling to the DEA. DEA said they would have a position by July 2016. Never happened and more burying of the head in sand has ensued)

Vegas and its State of Emergency add to the farce that is playing out between the States and the Feds. The will of the people is not being followed by the Feds and they increasingly understand the gap between the electorate and the Feds policy.

California goes early next year. Game over.

And maybe most importantly the research that is coming out on cannabis is off the charts great in so many therapeutic areas. I'm not going to bother listing all the conditions that cannabis is showing efficacy for. So the Feds stance on cannabinoids having no medical value is increasingly at odds with the scientific community.

If this change happens I think it has to happen sooner in Trumps Presidency than later. You would not want to enact this thing later in the term and have it part of a messy election fight is my bet. You would want to do it early and get some traction and have some positivity going into the election cycle. It would also take a platform away from the Democrats who are obviously more aligned with this type of policy and would garner votes from youth and cannabis positive voters.

Bottom line: No one likes looking stupid. The Feds are looking dumber by the day and real change will happen soon. I think it now happens within 6 months...and a year at tops from today.

ps I did not even mention the dollars. This is the biggest driver for many politicians obviously. The dollars are for the back room discussion so a politician does not come off looking greedy...they need to be perceived as putting public safety above all other considerations. So it will be the medical research, FDA approval requirements and public opinion that moves the needle, but make no mistake the Benjamins are on Trumps mind.

He was nicknamed "The Worm" and was known for his fierce defensive and rebounding abilities.

What's happening in a week or 2?

Disclaimer: I am loading up on US weed stocks right now

I think it happens in the next 6 months. I think it happens this fast because:

Epidiolex has been waiting for approval since March 14/16 and enough clinical trials have been past that approval is inevitable (last year the FDA gave its recommendation on scheduling to the DEA. DEA said they would have a position by July 2016. Never happened and more burying of the head in sand has ensued)

Vegas and its State of Emergency add to the farce that is playing out between the States and the Feds. The will of the people is not being followed by the Feds and they increasingly understand the gap between the electorate and the Feds policy.

California goes early next year. Game over.

And maybe most importantly the research that is coming out on cannabis is off the charts great in so many therapeutic areas. I'm not going to bother listing all the conditions that cannabis is showing efficacy for. So the Feds stance on cannabinoids having no medical value is increasingly at odds with the scientific community.

If this change happens I think it has to happen sooner in Trumps Presidency than later. You would not want to enact this thing later in the term and have it part of a messy election fight is my bet. You would want to do it early and get some traction and have some positivity going into the election cycle. It would also take a platform away from the Democrats who are obviously more aligned with this type of policy and would garner votes from youth and cannabis positive voters.

Bottom line: No one likes looking stupid. The Feds are looking dumber by the day and real change will happen soon. I think it now happens within 6 months...and a year at tops from today.

ps I did not even mention the dollars. This is the biggest driver for many politicians obviously. The dollars are for the back room discussion so a politician does not come off looking greedy...they need to be perceived as putting public safety above all other considerations. So it will be the medical research, FDA approval requirements and public opinion that moves the needle, but make no mistake the Benjamins are on Trumps mind.

OWC's psoriasis creme is going to "reduce pain, inflammation and irritation in psoriasis patients." There is more to the science than some would imagine. It is extremely complex.

Any time now we'll see efficacy results & completed safety study updated on clinicaltrials.gov

Looking nice. I'm in.

**PSORIASIS & CANNABINOIDS SCIENTIFIC INFO**

Will the cannabinoid cream work on Psoriasis?
To be seen as effective from a patient's point-of-view, the cream will need to reduce redness, inflammation, pain and the itch.

Pain and itch are two irritating sensations sharing a lot in common.
Another study of 22 patients cannabinoids reduced psoriasis itch by 86.4% when topically administered.

Psoriasis, an autoimmune disease is characterized by an abnormally excessive and rapid growth of the epidermal layer of the skin.
Skin cells are replaced every 3–5 days in psoriasis rather than the usual 28–30 days. These changes are believed to stem from the premature maturation of keratinocytes induced by an inflammatory cascade in the dermis involving dendritic cells, macrophages, and T cells.

CFN Interview with Dr. Yehuda Baruch, Chief Science Officer OWCP, starts at 2:57.
"We have proven that it inhibits proliferation of keratinocytes. We are working on how does it manage in certain interleukins which cause inflammation. We are looking at the various interleukins to see what does medical cannabis, especially THC & CBD, do to those various interleukins."

Which interleukins is OWC focusing on?
IL1, IL2, IL3, IL8, IL10, IL13, IL15, IL17, IL20, IL23, IFN-gamma, TNF-alpha

Conclusion:
I believe OWC's psoriasis creme will drastically reduce pain, inflammation and irritation in psoriasis patients. There is more to the science than some would imagine. It is extremely complex. Scientists are still making huge discoveries in this field. OWC is quickly getting their cream formulated and out to market to generate revenue ASAP. That is how confident they are in the research and product potential.

Sources:
http://www.ct.gov/dcp/lib/dcp/pdf/mmp/cannabinoids_inhibit_keratinocytes.pdf
http://onlinelibrary.wiley.com/doi/10.1111/all.12183/full
https://link.springer.com/article/10.1007/s00702-014-1251-x
https://en.wikipedia.org/wiki/Interleukin#List_of_human_interleukins
https://www.owcpharma.com/newsroom-photos/ (CFN Interview with Dr. Yehuda Baruch)

(Psoriasis and beyond: targeting the IL-17 pathway)

Still here and holding for the next several years. This company has many big things in the works. Just look at my past posts about the science they are working with. BIG things happening this year and next!

My average is right under .60 so I don't expect it to go lower than that. Great news seems to be just on the horizon!

This provides no information on product release.

Says it was supposed to be released in 2015.

It's 2017 and still no sales or revenue.

What happened to their product release?

Last Fall, 'V' was saying not to buy OW*P at 10 cents.

Don't listen to idiots if you want to make $.

$DOLV Long.

Sessions doesn't make the laws, he's supposed to enforce them. Imagine if he was soft on the current federal drug laws.. no one would take him seriously on illegal immigration. Sessions is a dinosaur. Congress must act, they are the ones who can change the laws.

US Cannabis industry employs as many people as dentist offices. Trump knows this. He wants more JOBS. Watch him address cannabis soon (next 4-6 months).

medIQ business name changed over the years. Established 2006.

"In the past 10 years we have enabled companies varying from startups to multinationals to successfully enter the European healthcare market."
http://innovationexperts.de/who_we_are

Most recent name was, "medIQ Life Science Solutions" in 2012.
http://www.prweb.com/releases/2012/3/prweb9356177.htm

People behind MedIQ Innovation Experts *links*

David Furst - Managing Director, Israel
"Mr. Furst has over 37 years of corporate experience as a veteran of the Home Land Security, and Electronic industries. Over the recent 17 years, Mr. Furst is active in the Life Sciences Industry, benefit from his reputation and intimate acquaintance with the Israeli Life Sciences industry."
https://il.linkedin.com/in/furstdavid
https://twitter.com/davidfurst
http://www.lifesci.biz/Management.asp

Benjamin (Benny) Arazy - Managing Director
"Benny Arazy - Arazy Group Benjamin Arazy is founder and CEO of Arazy Group, an established global medical device consultancy group with over 18 years of experience. Benny Arazy has 16 FDA 510(k) Applications with his name ( see link below )."
https://ca.linkedin.com/in/bennyarazy/
http://510k.medevnet.com/applications/index.cfm?fuseaction=list&contact=BENNY%20%20ARAZY

What happened to the volume here?

When will CNBX's first product hit the shelves?

When is CNBX product release?

Looks like it will be late 2018 before they have sales.

Cash of $2M, No debt, 8 U.S. patents, Q3 Revenues, 140M o/s, 1st NIH cannabis cream safety study, 2017 Myeloma treatment plans and New delivery system..

The Ebers Papyrs (ca. 550 BCE) from Ancient Egypt describes medical cannabis. The ancient Egyptians used hemp (cannabis) in suppositories for relieving the pain of hemorrhoids. Around 2000 BCE, the ancient Egyptians used cannabis to treat sore eyes. The Egyptologist Lise Manniche notes the relevance to "plant medical cannabis" in several Egyptian texts, one of which dates back to eighteenth century BCE.

10-Q will be out today or tomorrow.

Let's hope a couple big 8k's follow next week.

What Type of Investors Attend Monaco Growth Forums?

Monaco Growth Forums Founder Andreea Porcelli breaks down the types of investors companies can expect to find at the conference.

Will the cannabinoid creme work on Psoriasis?
This is the #1 question I ask myself and every shareholder should be focused on the upcoming clinical results. To be seen as effective from a patient's point-of-view, the creme will need to reduce redness, inflammation, pain and the itch. 2007 [UK] Cannabinoids may be useful for psoriasis, as THC, cannabidiol, cannabinol, and cannabigerol have been found to inhibit keratinocyte proliferation in hyperproliferating human keratinocyte cell lines.

Pain and itch are two irritating sensations sharing a lot in common.
2005 [Croatia] In a study of patients with a chronic itching that occurs in patients with advanced kidney disease, topical application of a cannabinoid creme applied twice daily for 3 weeks completely eliminated itching in 8 of 21 patients (38%). Another study of 22 patients reduced itch by 86.4% when topically administered.

Psoriasis, an autoimmune disease is characterized by an abnormally excessive and rapid growth of the epidermal layer of the skin.
Skin cells are replaced every 3–5 days in psoriasis rather than the usual 28–30 days. These changes are believed to stem from the premature maturation of keratinocytes induced by an inflammatory cascade in the dermis involving dendritic cells, macrophages, and T cells (three subtypes of white blood cells). 2013 [Germany] In mice, topical THC application effectively decreased contact allergic ear swelling and myeloid immune cell infiltration which influences inflammation. Topical THC limited myeloid immune cell recruitment by a decreasing T-cell production of interferon-y and keratinocyte production of CCL2, CCL8, and CXL10 chemokines. In terms of atopic dermatitis, the activation of CB1 receptors in mice has been found to improve epidermal barrier function, decrease Th2-mediated inflammatory response, and suppress mast cells. Mast cells (type of white blood cell) play a key role in the inflammatory process.

Although there are existing reports and studies on CBD and THC (on mice and humans), OWC's formulations will contain several active compounds from the cannabis plant, that must be fully researched and documented (but not exclusive to) the cannabinoids CBD and THC, and identifying potential therapeutic applications of the synergistic effects of these active compounds. THC may also demonstrate anti-inflammatory effects independent of CB1 and CB2 receptors, which needs to be further studied and I believe they are doing it right now.

What other skin conditions have most similar symptoms?
Acne
Basal cell carcinoma
Allergic contact dermatitis
Atopic dermatitis
Contact dermatitis
Eczema

Which interleukins is OWC focusing on?
IL1, IL2, IL3, IL8, IL10, IL13, IL15, IL17, IL20, IL23
IFN-gamma
TNF-alpha

Conclusion:
Based on the preliminary studies I believe OWC's psoriasis creme will reduce pain, inflammation and irritation in psoriasis patients. They will be able to adjust the formulations to determine the most effective syngergistic effects of several cannabinoids (not just CBD/THC). The more I look into the science, the more confident I am that this investment is well deserved and the research on the subject just isn't what it should be. OWC is on the frontier of these breakthroughs and the most valuable asset OWC will have is the intellectual property of their formulations.

Sources:
http://www.ct.gov/dcp/lib/dcp/pdf/mmp/cannabinoids_inhibit_keratinocytes.pdf
http://onlinelibrary.wiley.com/doi/10.1111/all.12183/full
https://link.springer.com/article/10.1007/s00702-014-1251-x
http://www.owcpharma.com/newsroom-photos/ [CFN Interview with Dr. Yehuda Baruch]
[Psoriasis and beyond: targeting the IL-17 pathway]

**COULD THIS BE THE NEW DELIVERY SYSTEM?**



Is an Asthma Inhaler OWCP's next delivery system and target?

Why the Inhaler delivery system?
Fastest method of delivery cannabinoids into the blood stream while being able to accurately dose each inhale.

Can Cannabinoids treat Asthma attacks?
There are 24 million Americans who are living with asthma today. THC can function as a temporary bronchodilator. Anti-inflammatory, regulates muscle spasms (which is how it treats IBS), antispasmodic properties.

Why an Inhaler vs. Smoking?
..So someone who can't breath properly is going to be treated by a drug that is most popularly smoked.. How dumb does that sound? Most would think that's an unimaginable scenario and just an outright dumb decision. (Most would be mistaken). It's hard to imagine an asthma sufferer reaching for a joint or bong when they need immediate relief. Some would think they would end up being more choked up by the smoke and lack of fresh air. However, some pre-clinical studies are proving that cannabinoids, when introduced to lung tissue directly can have a significant effect on reducing the inflammation and regulating immune responses that can cause asthma attacks.

How is asthma similar to psoriasis and IBS?
The inflammatory mechanic similarities between psoriasis, fibromyalgia, asthma and IBS are very similar. They can happen due to unregulated immune response cascades. With asthma most people are atopic (allergic to external triggers in the airways). Anxiety, stress, laughter. Airways narrow and cause wheezing. Mucous is produced in the lining and clogs the airways (mild, moderate, and severe). Narrowing of airways is reversible if trigger is removed or treated medically. Preventative treatment for an acute asthma attack: Mast cells contains granules rich in histamine and heparin. Role in allergy, play protective role in wound healing and defense against pathogens.In anaphylaxis (severe systemic reaction to allergens, such as nuts, bee stings or drugs), body-wide degranulation of mast cells leads to vasodilation and, if severe, symptoms of life-threatening shock. Histamine is a vasodilatory substance released during anaphylaxis.



What happens during an asthma attack?
Asthma is an immune response going overboard. A part of our body's natural response to a foreign body that then causes us harm by reacting to strongly and releasing things that cause us discomfort. IgE works with immune system to find mast cells. The mast cells contain granules rich in histamine. The IgE carries a foreign substance to the mast cell to attach to. The attachment wakes up the mast cells and the granule pockets open and release the histamine into the blood stream. Smooth muscle layer controls the diameter of the lumen (opening). Smooth muscle you can't control consciously. It reacts to the environment. Mucosa layer coats the inside opening of the airway. Glands in the mucosa keep our airways moist so they can clear out the debris with phlegm. During asthma, the muscles spasm (constricting) and the airway opening is getting much smaller. The smooth muscular layer has thickened and is clamping down on the opening. The mucosa layer has been compressed inward and decreases the lumen further. The glands continue to secrete mucous into the lumen which makes matters worse. Coughing and wheezing follow.

Conclusion:
Since OWC is already doing research on cannabinoids and their synergistic effects with the human immune system. Mainly focused on the functions dealing with white blood cells, cytokines and interleukins. Their studies could easily adapted for asthma since they will already have a wealth of information on how THC/CBD interact with certain immune functions. Just one more huge, exciting possibility for the company!

Sources:

(Asthma pathophysiology | Respiratory system)
Mast Cell (How Allergy Works)
(Asthma Cannabis Treatment Works Wonders On Lungs and Breathing)

Methotrexate vs. Cannabis *Psoriasis PHOTO*

pic.twitter.com/4LDG4PXNXb

Arm treated with methotrexate. Side effects. Feeling of being sick, fever, diarrhea, increased chance of infection, abnormal liver function. (Left)

Same arm after treatment with Cannabis Oil applied topically 3 times a day for 9 days. Side effects. Can now go swimming with her family for the first time. (Right)

**IMPORTANT SCIENTIFIC INFO**

Will the cannabinoid creme work on Psoriasis?
This is the #1 question I ask myself and every shareholder should be focused on the upcoming clinical results. To be seen as effective from a patient's point-of-view, the creme will need to reduce redness, inflammation, pain and the itch. 2007 [UK] Cannabinoids may be useful for psoriasis, as THC, cannabidiol, cannabinol, and cannabigerol have been found to inhibit keratinocyte proliferation in hyperproliferating human keratinocyte cell lines.

Pain and itch are two irritating sensations sharing a lot in common.
2005 [Croatia] In a study of patients with a chronic itching that occurs in patients with advanced kidney disease, topical application of a cannabinoid creme applied twice daily for 3 weeks completely eliminated itching in 8 of 21 patients (38%). Another study of 22 patients reduced itch by 86.4% when topically administered.

Psoriasis, an autoimmune disease is characterized by an abnormally excessive and rapid growth of the epidermal layer of the skin.
Skin cells are replaced every 3–5 days in psoriasis rather than the usual 28–30 days. These changes are believed to stem from the premature maturation of keratinocytes induced by an inflammatory cascade in the dermis involving dendritic cells, macrophages, and T cells (three subtypes of white blood cells). 2013 [Germany] In mice, topical THC application effectively decreased contact allergic ear swelling and myeloid immune cell infiltration which influences inflammation. Topical THC limited myeloid immune cell recruitment by a decreasing T-cell production of interferon-y and keratinocyte production of CCL2, CCL8, and CXL10 chemokines. In terms of atopic dermatitis, the activation of CB1 receptors in mice has been found to improve epidermal barrier function, decrease Th2-mediated inflammatory response, and suppress mast cells. Mast cells (type of white blood cell) play a key role in the inflammatory process.

Although there are existing reports and studies on CBD and THC (on mice and humans), OWC's formulations will contain several active compounds from the cannabis plant, that must be fully researched and documented (but not exclusive to) the cannabinoids CBD and THC, and identifying potential therapeutic applications of the synergistic effects of these active compounds. THC may also demonstrate anti-inflammatory effects independent of CB1 and CB2 receptors, which needs to be further studied and I believe they are doing it right now.

What other skin conditions have most similar symptoms?
Acne
Basal cell carcinoma
Allergic contact dermatitis
Atopic dermatitis
Contact dermatitis
Eczema

Conclusion:
Based on the preliminary studies I believe OWC's psoriasis creme will reduce pain, inflammation and irritation in psoriasis patients. They will be able to adjust the formulations to determine the most effective syngergistic effects of several cannabinoids (not just CBD/THC). The more I look into the science, the more confident I am that this investment is well deserved and the research on the subject just isn't what it should be. OWC is on the frontier of these breakthroughs and the most valuable asset OWC will have is the intellectual property of their formulations. Have a great day and enjoy the holiday! Happy 4/20 everyone!

Which interleukins is OWC focusing on?
IL1, IL2, IL3, IL8, IL10, IL13, IL15, IL17, IL20, IL23
IFN-gamma
TNF-alpha

IL1 participates in the regulation of immune responses, inflammatory reactions and hematopoiesis (formation of blood cells).

IL2 regulates the growth and differentiation of T cells and certain B cells through the release of secreted protein factors. (T-cells cause inflammation, activate macrophages and get other T-cells fired up, regulate much of the immune response) (Types of T-cells include Helper, Cytotoxic, Memory, Suppressor, Natural Killer).

IL3 regulates hematopoiesis by controlling production, differentiation and function of granulocytes and macrophages.

IL8 induces chemotaxis in target cells, primarily neutrophils but also other granulocytes, causing them to migrate toward the site of infection.

IL10 is a protein that inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF, and GM-CSF produced by activated macrophages and by helper T cells.

IL13 is a pleiotropic cytokine that may be important in the regulation of the inflammatory and immune responses.

IL15 is a cytokine that possesses a variety of biological functions, including stimulation and maintenance of cellular immune responses

IL17 is a potent proinflammatory cytokine produced by activated memory T cells.

IL20 regulates proliferation and differentiation of keratinocytes.

IL23 maintenance of IL-17 producing cells, increases angiogenesis but reduces CD8 T-cell infiltration

IFN-gamma (interfering gamma activates macrophages and they turn into granulomas).

TNF-alpha is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages.

Conclusion:
There is more to the science than some would imagine. It is extremely complex and scientists are still making huge discoveries in this field. OWC is quickly getting their cream formulated and out to market to generate revenue ASAP. That is how confident they are in the research and product potential. As more studies are done and funded by the sales of creme via licensing, OWC will garner huge respect from the industry as they increase and secure their IP portfolio.

Sources:
http://www.ct.gov/dcp/lib/dcp/pdf/mmp/cannabinoids_inhibit_keratinocytes.pdf
http://onlinelibrary.wiley.com/doi/10.1111/all.12183/full
https://link.springer.com/article/10.1007/s00702-014-1251-x
https://en.wikipedia.org/wiki/Interleukin#List_of_human_interleukins
www.owcpharma.com/newsroom-photos/ (CFN Interview with Dr. Yehuda Baruch)
(Psoriasis and beyond: targeting the IL-17 pathway)

Which interleukins is OWC focusing on?
IL1, IL2, IL3, IL8, IL10, IL13, IL15, IL17, IL20, IL23
IFN-gamma
TNF-alpha

"We have proven that it inhibits proliferation of keratinocytes. We are working on how does it manage in certain interleukins which cause inflammation. We are looking at the various interleukins to see what does medical cannabis, especially THC & CBD, do to those various interleukins. We have got already primary results. This study will be finished by the end of April and we can have the results published."
*CFN Interview with Dr. Yehuda Baruch, Chief Science Officer OWCP, starts at 2:57.

IL1 participates in the regulation of immune responses, inflammatory reactions and hematopoiesis (formation of blood cells).

IL2 regulates the growth and differentiation of T cells and certain B cells through the release of secreted protein factors. (T-cells cause inflammation, activate macrophages and get other T-cells fired up, regulate much of the immune response) (Types of T-cells include Helper, Cytotoxic, Memory, Suppressor, Natural Killer).

IL3 regulates hematopoiesis by controlling production, differentiation and function of granulocytes and macrophages.

IL8 induces chemotaxis in target cells, primarily neutrophils but also other granulocytes, causing them to migrate toward the site of infection.

IL10 is a protein that inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF, and GM-CSF produced by activated macrophages and by helper T cells.

IL13 is a pleiotropic cytokine that may be important in the regulation of the inflammatory and immune responses.

IL15 is a cytokine that possesses a variety of biological functions, including stimulation and maintenance of cellular immune responses

IL17 is a potent proinflammatory cytokine produced by activated memory T cells.

IL20 regulates proliferation and differentiation of keratinocytes.

IL23 maintenance of IL-17 producing cells, increases angiogenesis but reduces CD8 T-cell infiltration

IFN-gamma (interfering gamma activates macrophages and they turn into granulomas).

TNF-alpha is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages.

Conclusion:
There is more to the science than some would imagine. It is extremely complex and scientists are still making huge discoveries in this field. OWC is quickly getting their cream formulated and out to market to generate revenue ASAP. That is how confident they are in the research and product potential. As more studies are done and funded by the sales of creme via licensing, OWC will garner huge respect from the industry as they increase and secure their IP portfolio.

Sources:
https://en.wikipedia.org/wiki/Interleukin#List_of_human_interleukins
www.owcpharma.com/newsroom-photos/[/url](CFN Interview with Dr. Yehuda Baruch)

Yes.

Additionally, OWC could license their several IP formulations to other cosmetic distributors in all the MMJ U.S. states and European countries.

Will the cannabinoid creme work on Psoriasis?
This is the #1 question I ask myself and every shareholder should be focused on the upcoming clinical results. To be seen as effective from a patient's point-of-view, the creme will need to reduce redness, inflammation, pain and the itch. 2007 [UK] Cannabinoids may be useful for psoriasis, as THC, cannabidiol, cannabinol, and cannabigerol have been found to inhibit keratinocyte proliferation in hyperproliferating human keratinocyte cell lines.

Pain and itch are two irritating sensations sharing a lot in common.
2005 [Croatia] In a study of patients with a chronic itching that occurs in patients with advanced kidney disease, topical application of a cannabinoid creme applied twice daily for 3 weeks completely eliminated itching in 8 of 21 patients (38%). Another study of 22 patients reduced itch by 86.4% when topically administered.

Psoriasis, an autoimmune disease is characterized by an abnormally excessive and rapid growth of the epidermal layer of the skin.
Skin cells are replaced every 3–5 days in psoriasis rather than the usual 28–30 days. These changes are believed to stem from the premature maturation of keratinocytes induced by an inflammatory cascade in the dermis involving dendritic cells, macrophages, and T cells (three subtypes of white blood cells). 2013 [Germany] In mice, topical THC application effectively decreased contact allergic ear swelling and myeloid immune cell infiltration which influences inflammation. Topical THC limited myeloid immune cell recruitment by a decreasing T-cell production of interferon-y and keratinocyte production of CCL2, CCL8, and CXL10 chemokines. In terms of atopic dermatitis, the activation of CB1 receptors in mice has been found to improve epidermal barrier function, decrease Th2-mediated inflammatory response, and suppress mast cells. Mast cells (type of white blood cell) play a key role in the inflammatory process.

Although there are existing reports and studies on CBD and THC (on mice and humans), OWC's formulations will contain several active compounds from the cannabis plant, that must be fully researched and documented (but not exclusive to) the cannabinoids CBD and THC, and identifying potential therapeutic applications of the synergistic effects of these active compounds. THC may also demonstrate anti-inflammatory effects independent of CB1 and CB2 receptors, which needs to be further studied and I believe they are doing it right now.

What other skin conditions have most similar symptoms?
Acne
Basal cell carcinoma
Allergic contact dermatitis
Atopic dermatitis
Contact dermatitis
Eczema

Conclusion:
Based on the preliminary studies I believe OWC's psoriasis creme will reduce pain, inflammation and irritation in psoriasis patients. They will be able to adjust the formulations to determine the most effective syngergistic effects of several cannabinoids (not just CBD/THC). The more I look into the science, the more confident I am that this investment is well deserved and the research on the subject just isn't what it should be. OWC is on the frontier of these breakthroughs and the most valuable asset OWC will have is the intellectual property of their formulations. Have a great day and enjoy the holiday! Happy 4/20 everyone!

Sources:
http://www.ct.gov/dcp/lib/dcp/pdf/mmp/cannabinoids_inhibit_keratinocytes.pdf
http://onlinelibrary.wiley.com/doi/10.1111/all.12183/full
https://link.springer.com/article/10.1007/s00702-014-1251-x

New 8k!! First time Dr. Rozenblat quoted as part of OWC in a press release. And HUGE NEWS of future plans for efficacy tests for other skin conditions!! <--Some said this wasn't true when it was first announced.

"The global market for skin disease treatment technologies, which reached $17.1 billion in 2015, should reach $20.4 billion in 2020." -marketwired.com dermatology article 2016.

I am LONG, I am and many others are still here invested BIGLY in OWCP.

Just because you don't see us, doesn't mean we aren't here.

For my own reasons I don't post much.

OWC is a solid company, verified DD, so I have no worries.

Efficacy result will be out soon!