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Guys NNVC is a company like no other. When penicillin was discovered the tools were very primitive. The FDA was non existent, and communication were like two tin cans and a string.
Today we have great tools, internet, and an FDA totally ficused on "do no harm>! Our scientists are being attacked repeatedly, but are staying the course to bring a unique product to fruition The course is set, men are doing the job, and the beginning .of a major set of virus cides ready to roll. IMHO
Why hasn't NNVC received money to fight Ebola?
1st. We are a for profit company with PLENTY of money to complete to process to show we have a product! Research outfits don't have the cash to pay their people on new projects.
2nd. The frugal way Dr. Diwan works is so streamlined it does not require a wheelbarrow of money to get to a solution.
3rd. We are doing it to prove our backbone works and this will propel Flucide to a very fast spot.
Good morning to all. And I am hoping that we are another day close to stopping people from dying from all viruses!!!!
Your response is very misleading!
_____________________________________________________________
increasingly disgruntled investors the board just isn't fun to read anymore
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It seems to me there are two camps using this board.
One camp usually/always presents a negative point of view and keeps looking in a distant rear view mirror. This camp has 6 at most posters, some of who are suspected of using multiple alias.
This camp is what makes the board hard to read as there are so many rebuttals that distract from the facts.
The other camp is way bigger and have many more forward looking positive points of view.
For example:
6,000+ tested animals with only positive, for NNV,C results.
A new Plant being certified NOW. Built in the last year. A state of the art facility. Expected to be open in 1/2015. Capacity to greatly increase from 200gs per batch in the Wood street lab.
Lab reports ( all labs are independent of NNVC) that show Flucide is 1,500x more effective than Tamiflu. All subject animals survived with Flucide (sacrificed after 28 days and not toxicity found)vs dead after 8 days(Tamiflu) or 5days untreated. BASi now doing toxicity testing with "NO BAD NEWS" REPORTED TO DATE! This daily non reporting translates to good news.
See post from changes_iv for a better list of a programs underway.
Flucide is not on hold, it is not stopped. The testing is happening at BASi. No NEWS IS GOOD NEWS!
And it will not be stopped, more cides will be delivered on time for the next step to happen.
The Army will take over all the time tables and DEMAND NVC supply what ever they need/want. This by supping all the money necessary to get the job done quickly!
There you go again. Using the word MAJOR, and very poor choice of words.
I put it in bold; just shows you have a reading problem along with a science problem! 6,000 aminals, 1000x more effective, insiders buying, no insider sales!
When you make vague unjustified statement on this board they are quite often taken a fact.
For Example:
BASi has done tox testing for many different pharmaceutical companies many times before. We know they'll do their side of the work, and most likely with little delay on their part. It's NNVC that we worry about, and with good justification.
Any proof of this would be welcome.
IMHO
He should also include the transactions of the insiders to show how they are duping the investors.
drkaz,
Congratulations on acquiring all of the shares. You're not the only one gathering up all you can, i have been doing the same. So have the insiders.
Take a look at all of the insider buys in 2014 by the company's directors.
Insider Transactions Reported - Last Two Years
Date Insider Shares Type Transaction Value*
Nov 7, 2014 BONIUK MILTON
Director
380,954 Indirect Purchase at $0 per share. N/A
Oct 1, 2014 BONIUK MILTON
Director
19,700 Direct Purchase at $3.10 per share. 61,070
Sep 30, 2014 BONIUK MILTON
Director
61,292 Direct Purchase at $3 - $3.16 per share. 189,0002
Sep 29, 2014 BONIUK MILTON
Director
15,841 Direct Purchase at $3.20 per share. 50,691
Sep 26, 2014 BONIUK MILTON
Director
3,167 Direct Purchase at $3.20 per share. 10,134
Aug 25, 2014 DIWAN ANIL
Officer
28,571 Indirect Purchase at $3.50 per share. 99,998
Aug 25, 2014 VYAS MEETA
Officer
21,429 Direct Purchase at $3.50 per share. 75,001
Jul 17, 2014 BONIUK MILTON
Director
28,572 Indirect Purchase at $3.50 per share. 100,002
Jul 17, 2014 BONIUK MILTON
Director
28,572 Direct Purchase at $3.50 per share. 100,002
Feb 20, 2014 DIWAN ANIL
Officer
15,000 Direct Purchase at $3.80 per share. 57,000
Feb 18, 2014 DIWAN ANIL
Officer
35,000 Direct Purchase at $3.30 - $3.62 per share. 121,0002
What? NO SALES?
repost
drkaz,
Congratulations on acquiring all of the shares. You're not the only one gathering up all you can, i have been doing the same. So have the insiders.
Take a look at all of the insider buys in 2014 by the company's directors.
Insider Transactions Reported - Last Two Years
Date Insider Shares Type Transaction Value*
Nov 7, 2014 BONIUK MILTON
Director
380,954 Indirect Purchase at $0 per share. N/A
Oct 1, 2014 BONIUK MILTON
Director
19,700 Direct Purchase at $3.10 per share. 61,070
Sep 30, 2014 BONIUK MILTON
Director
61,292 Direct Purchase at $3 - $3.16 per share. 189,0002
Sep 29, 2014 BONIUK MILTON
Director
15,841 Direct Purchase at $3.20 per share. 50,691
Sep 26, 2014 BONIUK MILTON
Director
3,167 Direct Purchase at $3.20 per share. 10,134
Aug 25, 2014 DIWAN ANIL
Officer
28,571 Indirect Purchase at $3.50 per share. 99,998
Aug 25, 2014 VYAS MEETA
Officer
21,429 Direct Purchase at $3.50 per share. 75,001
Jul 17, 2014 BONIUK MILTON
Director
28,572 Indirect Purchase at $3.50 per share. 100,002
Jul 17, 2014 BONIUK MILTON
Director
28,572 Direct Purchase at $3.50 per share. 100,002
Feb 20, 2014 DIWAN ANIL
Officer
15,000 Direct Purchase at $3.80 per share. 57,000
Feb 18, 2014 DIWAN ANIL
Officer
35,000 Direct Purchase at $3.30 - $3.62 per share. 121,0002
Your right about the prices being low for years. But early adopters, like myself, still welcome all to start the gain now that we have soooo muchhhh good information.
The old stuff about 6,000 animals and 100% cure and 1000x better than Tamilflu and the ebola life extension the Army saw are going to be just the starting steps to a rocketship. IMHO
TRy thanks for this post. Could you please post a link?
I like how this sounds. A little NNVC UNTWISTED TRUTH:
NNVC was not a stock halted despite some of and disappointing some of the crowd.
Changes_IV would you put this in English for all to understand in our non Doctor level brains? TIA very much.
I read that our cides work well by mating with the virus and making it into a dead virus to no longer be a problem for the body. Again, TIA.
Quote:
--------------------------------------------------------------------------------
NanoViricides, Inc.: “NV-INF-1, INJECTABLE FLUCIDE™ FOR TREATMENT OF HOSPITALIZED PATIENTS WITH INFLUENZA"
NanoViricides, Inc. (NYSE-MKT stock symbol: NNVC) is a pioneering company developing nanomedicines against viruses. A "nanoviricide(r)" as defined by the company, is a drug that is designed to bind to the virus particle, encapsulate it, and possibly dismantle it. The nanoviricide drugs are developed using a unique polymeric micelle technology. Each polymer chain comprises a homopolymer of a proprietary monomer that contains PEG in the backbone. At each monomer unit, the polymer chain has pendant alkyl chains that lead to self-assembled surfactant-like polymeric micelles. At each monomer unit, the Company attaches multiple proprietary anti-viral ligands that direct the polymeric micelle to specifically bind to a virus or virus family. The Company designs the virus-binding ligands to mimic the virus-binding sites of the cognate receptor(s) of the virus. Thus, no matter how much the virus mutates, it is expected to continue to be affected by the nanoviricide, since the cognate receptor binding does not change. INF-001, Injectable FluCide™ , is the Company's first lead candidate for the treatment of hospitalized patients with influenza. INF-001 has shown as much 3 log reduction in lung viral load, and has shown full 21 day survival in lethal mouse model studies, wherein oseltamivir treatment led to only 8 days survival. It was shown to be effective against both Type I (H1N1) and Type II (H3N2) influenza viruses in vivo. The Company has recently completed construction of a cGMP-capable manufacturing facility for the scale-up and production of nanaomedicines in kg-scale, to enable supply for human clinical studies. The Company is also developing a drug candidate against Ebola in response to the current epidemic.
Yesterdays email and a late reply from Dr S.
eugeneseymourmd@mac.com
8:50 PM (11 hours ago)
If I remember correctly we did 8, sent them out for animal testing, took the best two, expanded them to 8, sent out again and then choose the best one
Not doing that with Ebola in the interests of time. Making many more and sending them ALL out at the same time
Speeds up the process
Thus it takes longer on the front end to make all the candidates but shorter on the back end since all of the testing can be done together
Went to visit the plant yesterday
Absolutely blown away by the speed of the move-in of most of the equipment in the past two months
The place really took my breath away
There is nothing like it anywhere in the world
It will eventually be seen as a model for all nanotechnology plants world-wide
The attention to detail is really amazing
I’d love to do a video tour but probably isn’t smart from a competitive point of view
Eugene Seymour MD MPH
Chief Executive Officer
NanoViricides, Inc
eugene@nanoviricides.com
www.nanoviricides.com
310-486-5677
"NNVC" on the New York Stock Exchange
On Nov 19, 2014, at 1:58 PM,I wrote:
?Sir from your release of information,
And this 100% survival result with FluCide is a fact.
So we can estimate the same success for the next TOX.
This is a serious prediction.
Could you tell us how many different iterations of ligands Dr. Diwan tried before such good results?
An approximate is ok. It could have been in the hundreds or thousands. I have no idea, but think the answer would help your loyal supports.
Another_voice_2, boB
Ebola is so contagious that NNVC does not have any samples to work with. Only in labs with the IV designation can have a sample. This is one reason for the lack of candidates. NNVC's approach uses a computer model to design a ligand or set of ligands to attach to the backbone. Andif you look at the structure of the virus you can how tricky it can be to find it's Achilles' heel. IMHO
OK everybody, EB2 has taken our eyes off the goal.
Flucide is the goal! TOX is underway!
No News IS Good News!
Every day with no bad news re the tox testing is GOOD news.
TOX was so safe, and now it is being proven with large doses.
Too large IMHO, but required for the FDA. So, infuse away until you kill a mouse or ferret or ???.
FLUCIDE!!!
OH Yeah, EB2 will reset the goal posts in our favor, but it is not required. 100% cure and 1,500% better than that other stuff that does not work very well.
A surprise fantastic reply to my post!
At Last you admit that the Army used our cide to test and GOT RESULTS. mANY OF THE VACINES GET NO RESULTS. Whe I was a kid you could drive a car and wear it out in 50,000 miles. Now you can drive over 200,000 miles with the improvements. The same will be seen from the new 8 candidates.
The Army used them before and got mediocre results. The mice lived longer, but they all died of Ebola anyway.
We are still at least two months away from Ebolacide being delivered to USAMRIID. I'm always amazed at the people who have seen delay after delay after delay yet nonetheless assume that the very next thing will be done lickedly split. I've seen this pattern over and over again over the years on this board.
Don't forget the Army used them before and got positive results. The program was pulled by the government and NNVC did not do any more work on improving the ligand attachments. This is why we are days/weeks away from the Army asking for the sample cides, at least 8 of them, to test. The best will be our product to manufacture and ship to CURE some unfortunate souls otherwise destined to DIE. IMHO
ow can you call a fox channel "insignificant".
The Keystone pipe line vote was ...
Why are the networks not castigating the NO senators?
When the Army orders some EB2 will all the channels come calling? You bet!!!
?Sir, very sorry not to see you on tonight. I broke my bum here in my winter getaway (AZ) to get hook up to watch.
Could/would you tell US what you planned to say. I will repost it or you could post a letter on the web site.
Thanks, your loyal supporter, another_voice_2
UGENE SEYMOUR
9:21 PM (19 minutes ago)
to me
They bumped me when I walking to the studio in 24 degree weather. Sent an email. I may be on tomorrow night
Don't know yet
Sent from my iPhone
Eugene Seymour MD MPH
Chief Executive Officer
NanoViricides, Inc
eugene@nanoviricides.com
www.nanoviricides.com
310-486-5677
"NNVC" on the New York Stock Exchange
If guidance is missing leading then lawyers get involved. So, by being on the long side they can stay clear.
Lawyers never sue because guidance is wrong on the short side.
Right now EB2 has the POTENTIAL to throw the guidance out the window.
Africa need EB2 to work. What % of a cure would you like? 100%, me too, but what % would you consider a success? With the recent published facts about hydration entending life a few days will let the water work and help people recover, IMHO.
When the first patients can to the USA for treatment if was clear to me that good medical practices were very important. This meant IVs and water, as no cure is available. In Africa many are just left untreated and die. ~70%, so EB2 is the ONLY hope at present.
As soon as we ship and the Docs at Ft. Detrick can observe EB2 results all timelines will be forgotten.
EB2 WILL SAVE LIVES, and the protocols will be overridden.
IMHO
to EUGENE
http://www.foxnews.com/health/2014/11/16/172-people-on-cruise-ship-fell-ill-with-norovirus-cdc-says/?intcmp=latestnews?
All the cruise lines would pay handsomely to stockpile a cide. It is very costly for them. Bob
eugeneseymourmd@mac.com
6:53 PM (47 minutes ago)
to me
My thought exactly
Have to stay focussed on Ebola and FluCide for the time being
Sadly, none of the drugs are going to work and GSK dropped out of the vaccine race
This is terrible for the West Africans but terrific for us!
Eugene Seymour MD MPH
And, to what FNposted and NNVC has said.
I just drove from Seattle to Mesa. It took about 50 gallons of gas. My tank only holds about 15 gallons. I did not need the 50 on board to start. When the miles built up and the gage read down I would stop and fill it up. The last tank might not even have been refined before I left. I only need it close to the end of the journey!
Get it! You only need the cides as you proceed on the journey.
For all those interested in the size of the company, look at a light bulb! How many people worked in the lab with Edison. His cot was in the corner of his lab. He did not waste time explain in endless meetings about the work he was doing!
1st. the amount of cide required to do the tox testing was a result of having work so well with any side effects.
2,nd even if Ebola is "winding down" for any reason why let ANYONE DIE because you don't want EB2 to be used in a human?
To answer you question a different way.
Why dose the medical community insist on testing in a certain protocol. because they have a mantra, "do no harm", The heck with fixing a problem fast.
NNVC has used a product that has been used in humans for years! This is our backbone! the ligands are a chemical structure that are attached to the backbone.
Do you think that our doc have not used HUMAN BLOOD to test the viruses of it they are being disassembled, (destroyed, made inactive) and can then be eliminated thru the kidneys.
If 70% victims die, would it not be better to test something so agnostic as a cide with informed consent. IMHO
NO NEWS IS GOOD NEWS!!! If the cides were not working their would report and we would get a PR to that effect!
NO NEWS IS GOOD NEWS
NO NEWS IS GOOD NEWS
If our cides fail the stock goes to ZERO and he gets NOTHING. So, what is your point ...
Ok, Ebola is a big bad virus in the wild of Africa. Could it be with proper care the death rate is reduced dramatically?
As an aircraft carrier sailor I could say even some very senior pilots had trouble doing their monthly carrier quals. It was before we had very good flight simulators. But if you had the skills on a simulator your chances would be a lot better than someone who was not even remotely trained.
What NNVC is doing with the computer chip has been proven with animals. No reason to believe it will not work in humans. It is only in the blood stream, it has nothing to do with cells.
Chnges_iv I have reposted your message on the yahoo facebook Nano club BLOG. I hope you don't mind but it is an important post.
Changes_IV, Sir we need to ASSUME (yes in caps) That the scientists in Ft. Dietrich, MD. have what is so desperately need to test the 8 sample cides that Dr. Seymour is sending at the end of this week. If enough is not on hand I would ASSUME they can grow more to make what is needed.
EB2 as all of the cides are not a vaccine. The mechanism of action depends on finding the weak spot on the cell and using that spot to start the apoptosis process.
This is a good reason EB2 will stand out from all the other suitors. We have a unique approach thanks to the good Doc in Charge.
IMHO, and as I have written before it will not take long to look in the dish and see EB2 doing the JOB!
Don't forget the 30% who survive must deal with the now apparent after effects from the virus.
1st. What the he77 is a Reverse merger?
2nd. How does this apply to a go it alone for all these years NNVC?
3rd. Why would you post this here?
great analogy!
DAVIDC2, One set cries that the top guys are making too much salary, now you suggest that they are cheating, gamming the system by manipulating the news.
As I have said if this is a scam it is the best one running. All the people, labs, army, consultants, PHE, and more must be lying about the results of the various trials. This is a BIOTECH, not a Ponzi scheme.
FDA’s decision to step in to conduct trials on its own instead of relying on companies to conduct trials for their respective drugs is motivated by the need to speed up the process of discovery for an Ebola cure, by cutting down time required on administrative and regulatory procedures. Scientists conducting the trials will continuously monitor the results and not wait for the trials to reach completion. As soon as a drug is found to be effective, it will be rolled out for use against the deadly virus, depending on supplies available."
However, the optimist in me says that when they put EB2 in a petrie dish with Ebola and see the reduction in viral count a loud applause will breakout in the lab. Then the head guy will make a new plan. IMHO!
And in reply to TOX testing so far
NO NEWS IS GOOD NEWS.
eVERY DAT WITHOUT NEWS MEANS WE PASSED ALL THE TEST UP TIL TODAY!!!
how many shares will you sell me at what price. Since you think it is a total failure I should get a deep discount! This is a serious proposal.