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I agree Spanky. I enjoy CP's posts as well.
Atone
Those who react purely on emotion and do not carefully deal with each other with patience and benefit of doubt should not be marriage partners!
AtonewithPPHM
Jim,
With all thats happening with trials I imagine a ICPT move someday and by suprise! Oh happy day.
AtonewithPPHM
Yervoy trial supposed to start by end of month! 7 days and ticking! Anyone with any sense should see that that is a big deal! (no pun intended) I love to use the word deal! Its coming soon. What will Dr. Brekken say tomorrow?
AtonewithPPHM
A new week and we are surely closer to our goal then ever before! I am positive, long and strong! I am buying pullbacks and cheering jumps. Thats as good as it gets. What a great life!!!
AtonewithPPHM
I have high hopes for Dr. Brekken's presentation this Tuesday. This is his first US, I believe , presentation for Peregrine as our new lead Scientist taking over for the Late Dr. Thorpe. Dr Thorpe presented last year at NYAS and I don't think Dr. Brekken is going to make his debut with ho-hum data.
I could be wrong but I don't think so!
AtonewithPPHM
Goat, FANTASTIC! Please clear up for me where the trial was congressionaly terminated? Could this be why some of our company info has been sealed for so long? National Security!
AtonewithPPHM
Sell and try to get back in at your peril! Any day, week or month in my opinion and I am patient enough to make sure I am here when that moment comes.
AtonewithPPHM
Stone,
Probably by Thursday!
Atone
I think we should all remain in our seats and stay buckled up this week!
Atone
Massive exit? We traded 35+ million last 2 days and you call169K a mass exit? Let's get real!
AtonewithPPHM
Smart advice Goat! I feel sorry for anyone selling right now, profits or no profits. They are going to miss out on one of the biggest runs ever seen!
AtonewithPPHM
CJ.
May the Lord welcome Dianne into paradise and comfort you during this time. She and you are in our prayers.
AtonewithPPHM
Sunstar,
"If a combination of bavituximab and your company's anti-PD-1 or other immuno mAb, shows a 100% response rate, and a doubling or tripling of cancer survivors, maybe you want to make Peregrine an offer that won't be refused before another company does. What are prevalent cures in cancer worth to BPs?"
This is what I believe and am waiting for! You are right on!
AtonewithPPHM
I am going to believe that us true longs will be rich when that happens, so 'no worries'
Atone
Hold onto your shares guys. We are almost there!
Atone
Bio,
I am on trials.gov and don't see the March date? Can you provide the link?
TIA
Atone
I am looking for some nice announcements in the next 2-3 weeks. Is there anyone who doesn't believe we will create a big demand by then for those preferred shares? Is K&L Gates behinds us to fail? They don't strike me as people who fail.
Has to be done with some outstanding news. Hey, I wonder if we have a Cotara deal to round our treasury up to the 200 mil range? How about some consistent outstanding data from other down stream check points? And what about that Yervoy trial? Could BMY be getting on board? Wait, what about liver data? Mind boggling what could be happening in the next few weeks!
Some things to think about.
Atone
We have a powerful team and will prevail. Only a matter of time. When you least expect it, BAM!! SP soars and you say "what the $$$$" Hang onto your shares!
AtonewithPPHM
Hmmm I wonder if we already locked up something with BMY and weren't interested in MRK? We have to be real careful who we allow to test with our Bavi.
AtonewithPPHM
Jeff,
I believe in the management. I believe that they are doing what they have to to get us across the finish line. I also believe that when they do the reward will be so great it will make an earlier deal pale by comparison. I believe this whole heartedly!
AtonewithPPHM
Bio ,
I wouldn't care if they went to 250 mil shares tomorrow. Even that will not be enough to satisfy the demand once Bavi is validated! We are going to need multiple forward splits for that.
AtonewithPPHM
There aren't any options available beyond July 2014 either. There has always been October options out there? Wonder Why not now? ;)
Atone
I think a few people are going to be surprised today!
Atone
I just placed my order to buy!! Picture a race car with its wheels burning rubber, gripping the road, gaining traction and leaving the other cars (BPs) behind! Thats our little PPHM. Powered by the greatest new fuel to be discovered, BAVI! In the drivers seat, K&L Gates, the distinguished Dr. Robert Garnick, Dr. Stephen King and several mystery co-pilots plotting every curve and track condition. I have placed my bet and I am waiting to join my team in the winners circle.
GO TEAM PPHM!
Atone
Bingo! I agree. Its a win for us.
Atone
CP. I'm betting we will have investors lined up for these shares well before the 30 days cited. I think we won't have long to wait till we see the light!
AtonewithPPHM
As per Revenue monster's post:
Looks like its priced at $25.00 per Preferred Share. Applied to sell it on the NASDAQ under ticker PPHMP however at this time there is no market available for E-Series Would all have to be done via private placements until its open to market.
Quote:
There is currently no market for the Series E Preferred Stock. We have filed an application to list the Series E Preferred Stock on the NASDAQ Capital Market under the symbol “PPHMP.” If that application is approved, trading of the Series E Preferred Stock on the NASDAQ Capital Market is expected to begin within 30 days after the date of initial delivery of the Series E Preferred Stock. We cannot assure you that a market for the Series E Preferred Stock will develop prior to commencement of trading on the NASDAQ or, if developed, will be maintained or will provide you with adequate liquidity.
OK, I'm buckled up just in case today is the day! I slept in my beach shorts and my Florida shirt, you know, the one with all the flowers on it. (FF thought you would get a kick out of that one) Big news any day now and I want to be ready when the fast track/AA/partnering/financing train leaves for the West Coast if Florida!
AtonewithPPHM
Porkchop,
Did you see the post by sunstar with the slides of the Yervoy and Bavi combo? BREATHTAKING! I am thinking we are about to do something more with BMY than just start a trial with their drug Yervoy!.
AtonewithPPHM
Jim,
I predict early retirement with Boku bucks is in your near future!
Atone
P.S. Do you know anything about RE on the West Coast of Florida, say somewhere near Port Charlotte?
Close enough for government work as they say!!
Atone
Jim,
No doubt of it! Just look back at DNA Genetech. . Over a 15 year period it split at least 6 times. Each time it climed to $80+ . Just do the math. 6- 2 for 1 splits and you will have 320,000 shares!! By the way, home of our illustrious Dr. Garnick!! I think he can do it again
Atone
Let's not anyone forget that docetaxol is off patent and we could possibly go with a generic.
Atone
zare2
"One possibility is that this is not good news, that the data from Checkmate 012 indicate the combo of the two drugs is not sufficiently effective or is excessively toxic in NSCLC," he wrote in an email to clients.
This may bode well for us as Bavi does not increase toxicity but does improve effectiveness!
Atone
Free ,
I am so happy you are back! Your understanding of the science is extremely valuable to us all. Wait till the PD-1 data gets out. The slides might have been a slip.
AtonewithPPHM
I hear you Goat! Any day, any day...
Atone
Free,
Under Immunotherapy Checkpoints: Potential Synergies Between Upstream and Downstream Targets
Y = Bavituximab Y = Anti-PD-1, Anti-PD-L1, Anti-CTLA-4
While they didn't specifically show a graph of PD-1 and PD-L1 results they showed pictures of the PD-1 receptor being covered (shown as purple Y) being lumped in with the results of CTLA-4 as if the outcome was the same. If you notice the receptors are PD-1 not CTLA-4. Doesn't it seem strange that if they are just talking about CTLA-4 they would have at least shown the receptor?
Then under 3. Sustained Immune Response, they had this sentence.
Anti-PD-1 and CTLA-4 inhibits the generation of immunosuppressive T-regs and maintains a cytotoxic T- cell response
Thats about as close to saying that the PD-1 receptor works the same as CTLA-4 as I think you can get. Why they aren't saying it outright yet is the question. What is going on behind walls of our little PPHM? ;) Good stuff I think!
AtonewithPPHM
I just went to trials.gov and this is what it showed:
16 Not yet recruiting A Two-arm, Single Center Phase 1b Trial of Bavituximab Plus Ipilimumab in Advanced Melanoma Patients
Condition: Advanced Melanoma
Interventions: Drug: Arm A-Bavituximab with Ipilimumab; Drug: Arm B-Ipilimumab
I hope we are not disappointed today! I would like to see this trial started today and details of last nights presentation.
AtonewithPPHM
Hope to have start of Yervoy trial tomorrow and highlights of tonights presentation. Could be a "BIG f......n deal: to quote Joe Biden!! Anyone care to bet that they say that the PD-1 results are similar to the CTLA-4 and that they look forward to a starting PD-1 trial in the near future?
AtonewithPPHM
Amen! Well said. Factual and to the point! Thanks Jim
AtonewithPPHM