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An interesting item, that relates to the NPR Radiolab piece on DNAPrint Genomics, and whether "race" exists or not:
Global variation in copy number in the human genome
Nature 444, 444-454 (23 November 2006) | doi:10.1038/nature05329;
Received 13 June 2006; Accepted 10 October 2006
http://www.nature.com/nature/journal/v444/n7118/full/nature05329.html
See Figure 7, and the comments surrounding it.
"We obtained the optimal clustering with the assumption of three ancestral populations, with the African, European and Asian populations clearly differentiated (Fig. 7)."
"A triangle plot showing the clustering of 210 unrelated HapMap individuals assuming three ancestral populations (k = 3). The proximity of an individual to each apex of the triangle indicates the proportion of that genome that is estimated to have ancestry in each of the three inferred ancestral populations. The clustering together of most individuals from the same population near a common apex indicates the clear discrimination between populations obtained through this analysis. The clustering was qualitatively similar to that obtained previously with a similar number of biallelic Alu insertion polymorphisms on different African, European and Asian population samples60."
Paradigms change with emerging evidence. We're in the midst of a very major paradigm shift.
Daniel Gannon
Portland, Oregon, USA
Ann,
Thank you.
Good luck to all of us!
Daniel Gannon
Portland, Oregon, USA
Hi Ann,
I'm very optimistic about DNAG. Is it coincidental that DNAG stock performed so poorly during that period of time (approximately the last 10 years,) which was roughly the same period of time, when the loudly-announced "official truth" was that there was absolutely zero biological/genetic basis for race, no racial differences at all (as the NPR Radiolab broadcast concerning DNAG delved into)? It's been an article of faith, undermining the credibility of the science and technology that actually detects differences. We've even seen some rabid, zealous people attacking anyone who mentions such realities -- there are some extremely fearful, zealous people out there. For just one example, see what this "Don Moody" character posts here, regarding DNAPrint Genomics and the NPR Radiolab program:
soc.genealogy.britain newsgroup
NPR Radiolab program on DNAPrint Genomics, "Race Doesn't Exist. Or Does It?"
http://groups.google.com/group/soc.genealogy.britain/browse_thread/thread/aa83fc9abbed143c?hl=en&q=radiolab
Positively rabid and irrational. It's not even worth arguing with such cranks. Note the delusions of grandeur, and other signs of mental illness, that this individual displays in those messages.
Now, a different tune is emerging. There's an about-face in this "official truth," and even the Obama incoming administration is looking to boost progress in personalized medicine (which keys in on such differences, in a medical context.) Very significant differences have been detected in individual humans' DNA, between different races, and documented in such seminal papers, as Nature's paper on CNV (Copy Number Variation in the Human Genome,) authored by a large, international, multi-racial, well-respected group of scientists. Here's one dramatic quote, regarding CNV:
New human gene map shows unexpected differences
22 Nov 2006 23:01:11 GMT
Source: Reuters
http://www.alertnet.org/thenews/newsdesk/N22205028.htm
"LONDON, Nov 22 (Reuters) - One person's DNA code can be as much as 10 percent different from another's, researchers said on Wednesday in a finding that questions the idea that everyone on Earth is 99.9 percent identical genetically."
Will DNAG see much better times, as a result? Are the dark clouds, and the irrational fear of acknowledging differences, dissipating? It appears that way. (A few diehard cranks notwithstanding.)
Wikipedia entry on Copy Number Variation in the Human Genome:
http://en.wikipedia.org/wiki/Copy_number_variation
The seminal Nature paper I mentioned:
Global variation in copy number in the human genome
Nature 444, 444-454 (23 November 2006) | doi:10.1038/nature05329; Received 13 June 2006; Accepted 10
(Note the lengthy, international, multi-racial, list of well-respected scientists, who authored this paper)
October 2006
http://www.nature.com/nature/journal/v444/n7118/full/nature05329.html
Daniel Gannon
Portland, Oregon, USA
"frogdreaming,"
Yet another unfounded personal attack!
I did not do what you accuse me of, "presenting false information." Nor was I "pretending" anything or being "misleading" in any way.
The 2008 dates are there in plain sight, attached to those applications. See for yourself. I only reported the dates in context, with links! No reasonable person would presume I was being deceptive about it, in any way, shape, or form. The items are labeled as patent applications. I faithfully repeated the language used on that website. The dates are clear. If the dates are deceptive in some arcane way, it is clearly not anything to do with me. At least, we do see the activity listed as occurring in the current year.
Daniel Gannon
Portland, Oregon, USA
"frogdreaming,"
You falsely claimed that I "have access to all manner of information not available to the rest of us." I do not possess any insider information, whatsoever, nor do I "have access" to such. I am only an "insider" in the sense that I own so many shares! That is the _only_ sense in which I can accurately be considered an "insider!" That has nothing to do with inside information, nothing whatsoever, as I have repeatedly pointed out, in the face of your repetitive, unfounded personal attacks!
Two patent applications listed with current-year filing dates:
SYSTEMS AND METHODS FOR IDENTIFYING AND TRACKING INDIVIDUALS
Publication number: WO2008005309 (A2)
Publication date: 2008-01-10
Inventor(s): GABRIEL RICHARD [US]; FRUDAKIS TONY N [US]; THOMAS MATTHEW J [US]
Applicant(s): DNAPRINT GENOMICS INC [US]; GABRIEL RICHARD [US]; FRUDAKIS TONY N [US]; THOMAS MATTHEW J [US]
Classification:
- international: A61B19/00; G06Q50/00; A61B19/00; G06Q50/00
- European: A61B19/00A
Application number: WO2007US15088 20070629
Priority number(s): US20060817760P 20060630
http://v3.espacenet.com/publicationDetails/biblio?KC=A2&date=20080110&NR=2008005309A2&DB=EPODOC&locale=en_EP&CC=WO&FT=D
Compositions and methods for the inference of pigmentation traits
Publication number: EP1873257 (A2)
Publication date: 2008-01-02
Inventor(s): FRUDAKIS TONY N [US]
Applicant(s): DNAPRINT GENOMICS INC [US]
Classification:
- international: C12Q1/68; G01N33/53; C07H21/02; C07H21/04; C12N15/09; G01N33/566; C12Q1/68; G01N33/53; C07H21/00; C12N15/09; G01N33/566
- European: C12Q1/68M6
Application number: EP20060022589 20020528
Priority number(s): EP20020739467 20020528; US20010293560P 20010525; US20010300187P 20010621; US20010310781P 20010807; US20010323662P 20010917; US20010344418P 20011026; US20010334674P 20011115; US20020346303P 20020102
http://v3.espacenet.com/publicationDetails/biblio?KC=A2&date=20080102&NR=1873257A2&DB=EPODOC&locale=en_EP&CC=EP&FT=D
I do not see any earlier dates listed, associated with these patent applications. Instead of making unfounded personal attacks and unfounded accusations, why don't you stay on topic, and substantiate whatever it is you're claiming, with evidence, instead of merely claiming it?
There is quite a lot of third party information about DNAPrint Genomics that has emerged this year. Not merely the growing list of AncestryByDNA distributors, but releases from various news media (including Ancestry Magazine, and NPR Radiolab,) and other organizations. These pieces of evidence have been posted here, mainly by Sam, and can be verified by clicking the links and doing the barest of due diligence.
Cease and desist the repetitive, unfounded personal attacks.
Daniel Gannon
Portland, Oregon, USA
"frogdreaming,"
That is an unfounded personal attack, which you well know I have previously refuted.
I have stated multiple times, that I have zero insider information. You repeatedly accuse me of having insider information, which of course, you have zero evidence of. You accusation is unfounded. I still have precisely zero insider (material nonpublic) information. For you to continue to insist otherwise, is nothing but an unfounded personal attack.
Also, look up the word, "evidence." What third parties (more than 30 distributors, news media, agencies, other companies,) disclose publicly about DNAPrint Genomics certainly _is_ evidence.
P.S., if you follow the links I gave here:
http://investorshub.advfn.com/boards/read_msg.aspx?message_id=33933513
You can plainly see that some of the patent applications are listed with 2008 (current year) dates. That is where I got that information. I have been quite plain about the source of that information; I mentioned the current-year patent applications only in this context.
Cease and desist the repetitive, unfounded personal attacks. Thank you.
Daniel Gannon
Portland, Oregon, USA
(Possessor of Precisely ZERO Material Nonpublic Information Pertaining to DNAG)
A poster on the DNAG board of Google Finance, has asked me to explain why I think DNAG is the world's most undervalued stock. I tried to explain it, relatively succinctly. There's a lot more to say, but hopefully what I said is a good start. (If there's more I should tell Wenz, please let me know! The DNAG story is fairly complex, and I'm sure there's more I should say about DNAG's value.)
Here is Wenz's question for me:
http://finance.google.com/group/google.finance.717321/msg/dfee72d55384eb7c
xtrop, could you please explain to me exactly why you think DNAG is the worlds most undervalued stock? if its so undervalued maybe i need some ;) just whenever i look at it it doesnt seem to do anything but .0005 and .0006
You can read my response here:
http://finance.google.com/group/google.finance.717321/msg/603483e7f70e13ff
Thread view:
http://finance.google.com/group/google.finance.717321/browse_thread/thread/961b31a5e61161bc/67776bba7394863a?
Good luck to all DNAG shareholders!
Daniel Gannon
Portland, Oregon, USA
I mentioned previously, how I'm buying DNAG with some of the profits I've made on other trades. One of these trades was, buying DTO (double short crude oil) at its bottom. It has since gained ~500%. Now I'm starting to buy its inverse, DXO (double long crude.) It's pretty much a consensus that crude oil will not remain at these levels (it will go up as the global economy gains traction.) Why is crude this cheap, then? Market irrationality (or what are people pricing in? Global thermonuclear annihilation?) Which means, good opportunity.
As always, looking for those extreme value plays, and putting my money where my mouth is,
Daniel Gannon
Portland, Oregon, USA
A very active heckling alias, on Google Finance, asked me this question, today:
--
What's going to happen to the stock price when you run out of money and remove your buy order at 0.004?
--
My response was as follows:
--
Even when I wasn't buying, relatively few DNAG shares were sold at the low of .0002, and none were sold cheaper than that. One reason I didn't buy for some months, was, I wanted to see how the stock would behave, without me in the picture. I also was waiting for a great opportunity to average down, which, of course, I received.
It's all about risk VS reward. I view this as an extremely undervalued stock, with high risk, but even higher potential reward, that more than makes up for the risk (especially if diversification and other prudent investment strategies are employed.) With stocks that have (for example) a 50-50 chance of either blowing up or gaining 1000% or more, it only takes a few of those in someone's portfolio, to make a _lot_ of money. Simple mathematics. I think DNAG is an extreme case, with better than 50-50 odds of success, and much greater than 1000% gain potential. Hence, it's my favorite stock. Risky, as I said. But very attractive to investors such as myself, who aren't blindly scared off by risk.
--
Link to this thread:
http://finance.google.com/group/google.finance.717321/browse_thread/thread/961b31a5e61161bc/67776bba7394863a
Note: There has been a lot of buying volume, since DNAG lifted off the .0002 bottom, that came from other people buying. (I'm definitely not the only buyer.)
Good luck to all DNAG shareholders,
Daniel Gannon
Portland, Oregon, USA
bag8ger,
Done.
http://investorshub.advfn.com/boards/read_msg.aspx?message_id=33933513
Our messages must have "crossed in the mail," so to speak.
Daniel Gannon
Portland, Oregon, USA
Thanks, Sam! Very informative.
It's good to see a recent snapshot of which companies have commercial interests in biomarkers.
DNAPrint Genomics is listed among 28 other companies in Table 1. In my opinion, DNAPrint Genomics' intellectual property in this area is highly valuable, especially given how important this field is becoming. Who holds the relevant patents in an emerging field, is always an important factor.
List of patent applications with Frudakis, Tony listed as the applicant or inventor:
http://v3.espacenet.com/searchResults;jsessionid=C420DE0643B29EF23EAA145EE96F5D99.espacenet_levelx_prod-sna_4?locale=en_EP&ST=quick&IA=frudakis+tony&compact=false&DB=EPODOC
(Note: multi-page list; click Next to navigate to next page)
List of patent applications with DNAPrint Genomics listed as the applicant or inventor:
http://v3.espacenet.com/searchResults?locale=en_EP&ST=quick&IA=dnaprint+genomics&compact=false&DB=EPODOC
Note, some of these applications were submitted this year.
Daniel Gannon
Portland, Oregon, USA
"frogdreaming,"
Not totally true. I have received emails from two people at the company, relatively recently. Also, keep in mind, we have continued to see news pertaining to DNAG, coming from a number of other parties, and not just the long list of AncestryByDNA distributors. Incidentally, that news, and those comments, have all been positive... some very much so.
> The company has been silent and dark for well over a
> year now.
You know very well they fixed the registration issue in Utah.
> Not a peep about revenues, possibilities, whether they are
> still in business, (they let their registrations lapse),
There are issues, sure, but it's far from the bleak picture that your post describes. "Lying through omission" is still lying.
Daniel Gannon
Portland, Oregon, USA
PL1,
You're very welcome. I'd like to thank the same people, and you as well!
Here's to the struggle for a level playing field (manipulation under control so we can have stock valuations that actually make some sense,) and well-earned success,
Daniel Gannon
Portland, Oregon, USA
Thanks, Sam, that's certainly good news!
> FDA May Collaborate with Personal Genomics Firms
> to Track Adverse Events [...]
Daniel Gannon
Portland, Oregon, USA
Ann,
It's great to see the positive developments continuing to emerge! These developments with the incoming Obama administration, as well as the exposure DNAG is getting through NPR Radiolab, could turn out to be very big positives for this company, and its stock.
Daniel Gannon
Portland, Oregon, USA
"frogdreaming,"
What I said is observably true. When the bid was .0002 and the ask was .0003, I entered large buy limit orders at .0003. I received a lot of shares, then the bid changed to .0003. The same thing repeated when I started buying at .0004. That occasionally there is an exception to this rule, is not in dispute. (Hence, we saw some sales at .0003, even when I had limit orders in at a higher price. Market maker screwing around to get profit.)
Do not presume to speak for me. Your representations about what I think have been completely inaccurate. Just stop it.
Daniel Gannon
Portland, Oregon, USA
Thanks for the link, Sam!
http://www.wnyc.org/shows/radiolab/episodes/2008/11/28
The four segments accessible there are:
--
Race
The U.S. Census defines five races, and an "other" category. When the human genome was first fully mapped in 2000, Bill Clinton, Craig Venter, and Francis Collins took the stage and pronounced that "The concept of race has no genetic or scientific basis."
Great words spoken with great intentions. But what does that mean and where does it leave us? It doesn't seem to have wiped out our evolving conversation about race.
Race Doesn't Exist. Or Does It?
Tony Frudakis and his company DNA Print Genomics believe they can identify hair, eye, and skin color and point to the genetic ancestry of test subjects by scanning their DNA. NPR's Nell Greenfieldboyce goes to investigate, using a sample of Jad's DNA to find out what they could discover. The results? Surprising to all. We found another surprised DNA test subject, Wayne Joseph, a high school principal and writer on the topic of race.
Race and Medicine
BiDil was the first drug approved by the FDA for a specific racial group. We want to know what the ramifications are for using skin color as a diagnostic tool for diseases and disorders that can't be seen. Producer Soren Wheeler talks to Dr. Jay Cohn, developer of BiDil and cardiac specialist. Sociologist Troy Duster and epidemiologist Richard Cooper discuss race, medicine, slippery slopes, and the dangers of false stereotypes.
Journalist Malcolm Gladwell has thought about stereotypes. Growing up in Ontario to an English father and Jamaican mother, he became one of the top sprinters in his age-group and he noticed that a surprising number of the most successful runners in Canada were from Jamaica. It got him wondering about the relationship between race and athletic success, and he's pretty sure his initial ideas were wrong.
Can You See Race?
Teacher David Sherrin presents an exercise called "Sorting People" to his 9th graders at the Facing History School. The outcome? Well, have a listen. How accurately can you guess a person's background from their appearance? Reporter Ali Abbas takes us to Baghdad, where that question has become an issue of life and death as tensions and violence have risen between Sunni and Shi'a in Iraq, and safety can come down to the spelling of your name.
--
I hope everyone had a great weekend! Best of luck in the coming week...
Daniel Gannon
Portland, Oregon, USA
Sam,
Very impressive! That kind of positive exposure is certainly good news for DNAG.
Daniel Gannon
Portland, Oregon, USA
Reading through the comments on that page, one user (Carolina) reports she heard the program on the 19th, but isn't sure of the date of recording. Perhaps it is scheduled to air again, on November 28, hence the listed date?
At any rate, it's very positive for DNAPrint Genomics. A major vindication, and added publicity.
Daniel Gannon
Portland, Oregon, USA
Many publishers, such as magazines, post-date their material (articles and whatnot,) and it's not uncommon for the material to be accessible online, some time before the material is accessible through other media. This must be for their November 28 edition, or something like that.
I presume this piece hasn't hit the airwaves yet, in which case, we've seen a valuable preview of what is going to be broadcast!
Daniel Gannon
Portland, Oregon, USA
Success in DNAG may be closer than any of us suspects.
It's good to see positive developments continuing to emerge, at any rate!
Daniel Gannon
Portland, Oregon, USA
It is very exciting.
DNAPrint Genomics and its technologies can certainly use the broadened exposure! And this looks like a big step in that direction, perhaps the beginning of the end for the taboo/myth, as well.
Daniel Gannon
Portland, Oregon, USA
You're welcome.
OK, the link itself isn't presented in a complete, clickable format (some of it isn't considered part of the URL, by this board... not Sam's fault, I'm sure.) Two more ways to access the radio program:
- Cut-and-paste to reconstruct the entire URL in the address bar of your browser
- Click this TinyURL link, which takes you to the same page:
http://tinyurl.com/6fpd2u
I hope that helps,
Daniel Gannon
Portland, Oregon, USA
Works for me; I'm able to listen to it.
Maybe the server is temporarily overloaded, or some other temporary technical issue?
Daniel Gannon
Portland, Oregon, USA
Sam,
Wow. This is big. Thanks for posting this!!
Happy Holidays, to you and to all,
Daniel Gannon
Portland, Oregon, USA
Hi Ann,
I hope so. We are seeing promising mumblings and beginnings of developments, that look to be very positive, re: Obama's incoming administration, and Pharmacogenomics. It seems like headway will be made.
Regards,
Daniel Gannon
Portland, Oregon, USA
Very interesting article, PL1. Thanks!
Daniel Gannon
Portland, Oregon, USA
Sam,
Good points... and good news!
Thanks again for sharing,
Daniel Gannon
Portland, Oregon, USA
Sam1933,
Good article. I agree with Secretary Leavitt. Thanks for posting this, and your other informative messages, lately, as well. It's interesting to see positive news items still coming out, after the most recent SEC filing from the company.
Daniel Gannon
Portland, Oregon, USA
"frogdreaming," wrong again. Sam provided a link to the relevant SEC filing (a Form 4 filing, by me.) Click the link, and read the filing. Simple and easy.
Daniel Gannon
Portland, Oregon, USA
I'm proud to announce, I've passed the 200 million mark.
My DNAG share count is now: 213,637,284
I just filed another Form 4 with the SEC.
Cheers,
Daniel Gannon
Portland, Oregon, USA
Some people my not be reading the article, "Cousin Barack and Me," but instead do a keyword search on "DNAPrint." The article has a space incorrectly inserted into the name, so "DNAPrint Genomics" is written as, "DNA Print Genomics." The article is definitely talking about us. It should not have been deleted from Google Finance and Yahoo Finance (I'm sure some heckler reported it as being off-topic, or some such ridiculous thing.)
Daniel Gannon
Portland, Oregon, USA
PL1, Thanks for posting yet another interesting and relevant article. It appears, increasingly, there is an enormous amount of important progress to be made, in Pharmacogenomics (also known as Personalized Medicine/Theranostics.) I'm glad that DNAPrint Genomics is one of a handful of companies, that is pioneering this field.
P.S., I currently own 198,411,787 shares of DNAG. (15.3% of outstanding shares.)
Daniel Gannon
Portland, Oregon, USA
Sam, That's very true. A good sign!
Daniel Gannon
Portland, Oregon, USA
PL1, Thanks for posting these articles.
Pharmacogenomics/Theranostics is obviously a field with tremendous therapeutic potential. I think we're only at the beginning of this particular medical revolution.
Thanks again!
Daniel Gannon
Portland, Oregon, USA
mbmun,
You're welcome. The more it's reported, the harder it should be for the SEC to ignore. This stock has value, and it should trade properly, without manipulation.
Daniel Gannon
Portland, Oregon, USA
Looks like a good one, Ann.
Thanks for the link!
Daniel Gannon
Portland, Oregon, USA
I just finished filing another complaint to the SEC. I've filed so many complaints, as have others, that surely they must have taken notice of the manipulation of DNAG, by now! Perhaps they are collecting evidence, in preparation for prosecution.
It's fast and easy to report blatant price manipulation and illegal propaganda, intended to manipulate share price:
SEC Complaint Center
http://www.sec.gov/complaint.shtml
select "online forms" --> "Manipulation of security price or volume"
At least we're not at .0002 any more... but this manipulation must stop.
Daniel Gannon
Portland, Oregon, USA
Today: Higher volume buys, very low volume sells. Looks like still more of the same manipulation. Someone tries very hard to keep this stock from gaining, which is, of course, extremely illegal to do. As always, I report these manipulative trades to the SEC, and I encourage others to do the same.
In the absence of manipulation, when the great preponderance of shares are transacted at the BUY price, then share price increases. It's not doing that, because of manipulation. This has been going on for years! But this stock has a lot of value... manipulators will not win forever, and hopefully, the SEC will come knocking and bring them/him/her to trial, sooner rather than later.
Daniel Gannon
Portland, Oregon, USA