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Agreed SFT. Many many dedicated longs are quietly loading in the background waiting for the news we all know is coming. It’s nice to see them stop in here for comic relief on occasion.
Maybe I should have said four?
Why do I keep humming “Three Blind Mice” and picturing the three stooges....LOL. Crazy. Scary too. Weeee
Further evidence is the registrant info. The real website is registered by Motovox....
Registrant Name: IT Department
Registrant Organization: APT Motovox Group INC
Registrant Street: 8844 Hillcrest Rd
Registrant City: Kansas City
Registrant State/Province: Missouri
Registrant Postal Code: 64138
Registrant Country: US
Registrant Phone: +1.8167678783
The fake one was private. Go figure.
Phd... remember this GEM?
I’ve been following this group since the $0.01’s and have been thinking of posting this for a while. This is my first post on this website actually, but of all the stocks I’ve followed I feel like $CELZ has the greatest potential to be $10.00 and above.
As my profile name suggests I am a physician (training as a 1st year resident) and I was introduced to this stock by one of our attendings who held a financial seminar earlier this year. As you can imagine, most of us graduate with crippling debt from medical school (where a good portion of our salary is shoveled to) which is why he held these seminars – to teach us some of his experience with bonds, stocks, and business, and the importance of investing our hard earned income.
So during his similar there were talks of some bio-medical stocks and Creative Medical Technology Holdings Inc (CELZ) was discussed as a potential stock to look at. There were others, but due to my field ED treatment seemed like familiar territory for me. I’ve since then looked into it and have read the various research and DD posted here and I’ve got to say I’m impressed! Today I want to contribute some knowledge from the inside perspective of the field everyone here is heavily invested in. Just note that this is WHY I BELIEVE this stock will grow, you can look at this any way you want but please do your own DD before you fully jump on board.
These are some of the things we learn in medical school up to residency and are found in most of our text books and step reviewers. My main source will be Harrison’s Principles of Internal Medicine, 19th edition since that’s what I currently use. I also took a look into the research articles on the CaverStem website themselves (most of them were just abstracts, but I managed to find the full articles and linked here to share in case you’re interested).
Overall, amazing work by the CaverStem team!
__
So first of all, how prevalent is ED?
In the National Health and Social Life Survey (NHSLS), which included a sample of men and women age 18–59, 10% of men reported being unable to maintain an erection (corresponding to the proportion of men in the MMAS reporting severe ED). Incidence was highest among men in the age group 50–59 (21%) and men who were poor (14%), divorced (14%), and less educated (13%). By 2025, experts predict that 322 million men will have ED worldwide. This is an increase from the estimated 152 million men with ED way back in 1995 (Aytac, McKinlay, & Krane RJ., 1999).
“The incidence of ED is also higher among men with certain medical disorders, such as diabetes mellitus, obesity, lower urinary tract symptoms secondary to benign prostatic hyperplasia (BPH), heart disease, hypertension” (Kasper, et al., 1999)
So we know that ED will continue to climb thanks to its close connection to the prevalent lifestyle diseases mentioned above (hypertension and diabetes being to most common). CMTH, Inc. (CELZ) is not only targeted here in the US, but will be spreading out internationally as well. Imagine how many patients this could potentially be used to relieve the burdens that come with ED.
So to know what is abnormal about erectile dysfunction (ED) we’ll need to know what the normal physiology is like. The normal male sexual function requires:
(1) An intact libido
(2) The ability to achieve and maintain penile erection
(3) Ejaculation
(4) Detumescence (tumescence means engorgement due to vascular congestion).
A lot of problems can come from (1) (no will to have sex in the first place), but those can usually be treated by treating the underlying cause; such as stopping certain conflicting medications or treating abnormal hormonal irregularities for example. Our focus of concern will be (2) as CaverStem targets the inability to get an erection and maintain it (the will is there, but the equipment is malfunctioning).
To understand what’s happening we should define what exactly leads to and maintains an erection.
The corpora cavernosa (or cavernous bodies) contain most of the blood in the penis during an erection. Penile erection depends on an increased flow of blood into the lacunar network within the cavernosa accompanied by complete relaxation of the arteries and corporal smooth muscle. The problem happens here when blood is unable to completely engorge these channels. This is essentially the target of CaverStem, hence the name (Cavernosa + Stem cells).
Of all of causes of ED the most common organic cause of ED is vascular disturbance. Atherosclerotic or traumatic arterial disease can decrease flow to the lacunar spaces, resulting in decreased rigidity and an increased time to full erection. Excessive outflow through the veins despite adequate inflow also may contribute to ED. Structural alterations to the fibroelastic components of the corpora may cause a loss of compliance and inability to compress the tunical veins. This condition may result from aging, increased cross-linking of collagen fibers induced by nonenzymatic glycosylation, hypoxemia, or altered synthesis of collagen associated with hypercholesterolemia.
So how does CaverStem fit in to all this?
“The possibility of using mesenchymal stem cells in the treatment of ED is enticing because these cells are known to secrete various growth factors that are beneficial in ED such as IGF-1 [133-135], VEGF [136], and FGF-2 [137], but also because of their anti-inflammatory activities [138], as well as possibility of differentiating into tissue relevant to the penile architecture [139].” (Ichim et al., 2013)
I really want to break this down for you:
IFG-1: Is commonly known to help build muscle and is also crucial in healing
FGF-2: This protein has been implicated in diverse biological processes, such as limb and nervous system development and wound healing.
And now here’s the really important one -
VEGF (Vascular endothelial growth factor): This stimulates the growth of blood vessels.
CaverStem HEALS and STIMULATES tissue and blood vessel growth, which has significant meaning the world of ED. Viagra and similar drugs work by increasing blood to the penis, and it works because just like a balloon you’re pumping it full of air. However, CaverStem essentially heals and repairs the damaged/blocked vessels by stimulating more to grow.
When introduced, Viagra and similar drugs were considered revolutionary in the world of ED. CaverStem, however, can one day be considered as a CURE.
This is why I consider this stock to be severely undervalued. If given the choice between a patch or a cure, which would you choose?
Also I know most of you have seen the procedure itself posted online. Bone marrow aspiration is a procedure that is commonly being done already for blood diseases, cancer, and other disorders. The only new thing that physicians need training for is how to operate the Magellan Cell Separator. Training shouldn’t be all that difficult.
I hope that this contributes something to your already established DD. Most of what I said could be taken from the articles posted on the official CaverStem website, but I wanted to simplify it because I know not a lot of people here work in the medical field.
I won’t be posting much here since between my rounds, patients, and other duties I only have free time to browse after my shift or during breaks. I will say, however, that I’m glad to be part of this ride with all the longs! Add me to the list of long holders: 300,000 strong. Not a lot compared to some of your millions, but it should be enough to help pay off part of my loan from medical school.
Sources:
I.A. Aytac¸ , J.B. Mckinlay And R.J. Krane (1999). The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU International. Retrieved from https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1464-410x.1999.00142.x
Ichim, T. E., Warbington, T., Cristea, O., Chin, J. L., & Patel, A. N. (2013). Intracavernous administration of bone marrow mononuclear cells: a new method of treating erectile dysfunction? Journal of Translational Medicine, 11, 139. http://doi.org/10.1186/1479-5876-11-139
Kasper, D. L., Fauci, A. S., Hauser, S. L., Longo, D. L. 1., Jameson, J. L., & Loscalzo, J. (2015). Harrison's principles of internal medicine (19th edition.). New York: McGraw Hill Education.
OK, see ya in the next one I guess.
Wolf, ya gotta let it percolate. This is not a flipper or swinger you are used to. Buy in, let them get the doctors in place and let the patients show up. Revenue will ramp up and you will reap the rewards. It will be growing each quarter. Not every 13 minutes.
The real website is motoped.com. Motopeds.com is a hater IMO.
All in the filings Polebarn. Nothing new, no secrecy. All part of the startup process. No different than any other company starting from the same spot. The question is, when will the notes end and when will revenue take over? There is no dying here to be a die hard. You gotta have your tickets when the game starts. This company is in its infancy. Come back and check this summer.
Offshore hedge accounts ;)
LOLOL Gobsmacked. I needed that :)
Really great post JB
We finally agree. You are just about spot on. It is way to early to tell, and yes, this is just the beginning of the advertising. CELZ need more doctors and more patients, that’s when more mainstream advertising will come in IMO. It is just getting started Wolf. Not a quick flip or swing stock. Buy in for pennies on the dollar is where we are at now.
I will ask you the same question, what do you think will happen when the Q1 is out and we see decent revenue?
Revenue absolutely is coming in. Each patient is generating revenue for CELZ. You cannot say there is no revenue. Come back when Q1 is posted and we can discuss it further.
1. Nope. Not correct. It is OFFICIALLY announced. They told us where to look in the shareholder update last month.
“The company will from time to time post announcements via social media. This includes FaceBook pages CaverStem, CaverStem International, Urology Updates, Fem Celz and Creative Medical Technologies. Other social media sites will include You Tube, Instagram and Twitter. We continue to work on all aspects of the company and updates will be provided as milestones are met.”
Some of us just refuse to see it if it’s not in a PR. They update social media frequently. Us old guys just have to get used to the social media world IMO.
2. No argument there.
Glad you are watching radracer. Doing a deep dive into the 2018 filings will tell you that CELZ issued several notes and warrants to pay for the commercialization of CaverStem and more.
The investors here are well aware that the notes are slowly clearing.
The good thing is that CELZ just renegotiated the most recent notes and could be working on the others, who knows?
More importantly, the commercialization phase has paid off because now we have several doctors treating patients with CaverStem and, starting this week treating patients with FemCelz.
We have two revenue streams now that are just starting to build up steam.
We should also see the acquisition close this Q which will help.
Do you think CELZ might buy back some of the notes?
Thanks whitehotcoal. I have been saying the same thing for months.
It is OFFICIALLY announced. They told us where to look in the shareholder update last month.
“The company will from time to time post announcements via social media. This includes FaceBook pages CaverStem, CaverStem International, Urology Updates, Fem Celz and Creative Medical Technologies. Other social media sites will include You Tube, Instagram and Twitter. We continue to work on all aspects of the company and updates will be provided as milestones are met.”
Some of us just refuse to see it if it’s not in a PR. They update social media frequently. Us old guys just have to get used to the social media world IMO.
$CELZ dipped sub penny and ready for a bounce. CELZ just put out a great video.... https://www.facebook.com/209079446282902/posts/525588401298670?sfns=mo
CELZ.... it will run soon. New video. https://www.facebook.com/209079446282902/posts/525588401298670?sfns=mo
CELZ... new video. Will be running soon IMO
https://www.facebook.com/209079446282902/posts/525588401298670?sfns=mo
Very nice! Thanks JB
Coming up on my year too!!
Or here too. https://www.facebook.com/UrologyUpdates/?__tn__=%2Cd%2CP-R&eid=ARDA9W7iCYB2ef46hkVKdv4PgoUTM2gKRYUZarTv2fsFJzVP1doctzlvVTrNNZhpa9jp771_4v-CXzrA
There are many posts and video you can watch.
Let me help you out JDFF. https://www.facebook.com/CreativeMedicalTechnologyHoldings/
Joh. One HUGE thing to take into consideration. The CEO, Tim Warbington holds approximately 79 million shares. All but approximately 5 million are common shares, not preferred shares, so he would be subject to any splits as well. Again, this is not a normal OTC pinky (it’s a QB) where the company hold preferred and RS the common shares into oblivion. Not in the cards here IMHO
Here is one more for you and me to chew on CP. Like I speculated in the past, once this gets rolling doctors and patients will talk and things will ramp up. It could happen fast, right? The old saying, I tell two friends, who tell two friend who tell two friends.
Dr. Said already has had so many doctors calling him and asking about CaverStem and regenerative medicine, that he hosted a webex.
Now some of those folks are out telling two friends. His next webex could have as many as 50 doctors present.
“It is important to organize the next WebEx meeting and set rules of Q&A as well as limit times when the number of hosted doctors will exceed 25, 50, or more. Interest in regenerative medicine is growing. I will work with professionals to organize the next one.”
Let that sink in. The pot is about to boil IMHO.
Thanks you weesnel. They make it easy when it’s all in black and white. Contrary to what I have been called lately, a paid pumper, I am a confident long who sees tremendous difference in where the company sits since the May 2018 AUA where much of this started. All you have to do is look at what has happened, all backed up by filings and shareholder updates.
If I have said it once, I have said it a hundred times. The PPS sucks... unless you are buying.
Last summer we moved nicely on the thought that doctors would sign up and start using CaverStem. I guess it was all a false start so to say. It bounced like a normal OTC stock that ran on rumor. IMHO, too much time played out as those doctors came online and the company switched to CaverStem 2.0. and we lost the buzz and fell back down to .01’ish. Still much higher than where it was a year ago.
We will see that run, and more again very soon. They are no longer rumors. Doctors have signed, more are being trained, FemCelz is ready.... i will stop there, it’s getting redundant.
I read the frustration here and agree with some of it. But I asked myself, is there ANY stock i have invested in that I knew 100% of what they are doing? Did any of those other companies change plans, or have something get delayed?
Hell yes, is the answer.
What happened to Freedman and Wachs? I think it’s obvious they changed their mind or did not clear the vetting... IDC. We picked up Antonini and Sanderson and have three more being trained. Things change, I am OK with it. Heck, maybe they had personal issues and they are the ones being trained in March. I guess we will find out soon.
Where is Mells? Personally, I don’t care. If he is working hard for us, has been fired, quit, or is just doing his thing where I cannot see it, I don’t care. Is LinkedIn the gold standard? I don’t have any idea, I am not on their either. Maybe that’s why it’s not important to me.
Personally I don’t want the COO giving pep talks to shareholder that are down. I do wish there was an outlet like a IR person, but we have all been there right? They can’t say much either.
We all want to know what’s going on in Russia and Switzerland and more. I trust we will find out when it’s prudent.
That’s my rant for the day. I have to run out soon.
Bottom line, I see the company progressing nicely. The open offices mean the world to me. It’s verification that some doctors and some patients see what I see.
Will there ever be enough doctors and enough patients to move the needle???
I have my bets in ;)
"And where is the Efficacy Report? How can we even discuss actual treatment of patients before this is published and shows successful trials?"
CaverStem™ clinical trial: We understand the eagerness to receive published data. We are currently working on our paper for publication as soon as possible.
I think we have discussed this many times. It is in PEER REVIEW. It can take a few months, to up to a year. When the REVIEW is completed, all the T's crossed and I's dotted they will COMPLETE the paper and issue it.
I am going to go out on a limb here, and its only my own WAG, but I bet they want it out as bad as any of us. Its NOT in their hands.
And... They OFFICIALLY told us to watch social media for info. They update their milestones weekly.
The company will from time to time post announcements via social media. This includes Facebook pages CaverStem, CaverStem International, Urology Updates, FemCelz and Creative Medical Technologies. Other social media sites will include You Tube, Instagram and Twitter.
The acquisition of the Virility Centers of America brand from affiliate company Creative Medical Health, Inc. will be completed by the end of this quarter. The company will then begin to offer this to new and existing physicians.
Lets see if this plays out.... I bet it does :)
FemCelz™; we've made great progress in the last 30 days. The procedure protocol has been completed and submitted to 4 of the existing CaverStem™ physicians that also practice female sexual function medicine. We are developing content for the FemCelz.com website and FaceBook page to launch very soon. FemCelz is commercializing.
Note... they did all of that and the accomplishments were posted on their respective FB pages, and the first patients are scheduled for this coming week.
Our progress in Russia continues. As was announced on our social media sites Dr. Gabrielle Antonini will treat the first 5 patients in Rome on February 16th. We wish to again welcome Dr. Antonini and we look forward to a successful relationship.
We have begun the physician marketing campaign and have sent out the first mailers in Januray We have received numerous email inquiries and we are reaching out and scheduling interviews. This process involves an in depth series of emails and calls with questions and answers from the physician and the Company. Once both sides agree a contract is signed.
We are currently scripting a 30 second and 60 second television commercial that will be edited with each physicians information. The advertisements are intended to air regionally on networks such as MSNBC, CNN, Fox News, ESPN, The Golf Channel and The History Channel. These networks have the ideal demographics for potential CaverStem™ patients.