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42,212 since Nov 8th
Have any of my longs here witnessed deals such as;
Minimal upfront
Commitment to pay for all future trials
Heavy milestones
A commitment to purchase shares on open market
I think a commitment to say 10 million in open market shares would do so much here rather than take more upfront?
I feel we may have several deals in the pipeline and could be very creative in putting the share price where it should be.
IE imagine:
10 mil upfront
10 mil in open stock purchase
Paid for trial expense to market
250mil in milestones
30-40% royalties
IPIX takes care of drug manufacturing costs and provides drug
Those numbers have no justification, just an example.
Just curious about open market purchase agreements. Not from our shelf.
Scroll down on each filing. They give the exact percentage of OS.
“Strategic M&A and licensing deals are therefore inevitable for innovation starved drug/biotech companies looking for growth in a highly competitive and global marketplace.
Given that it takes several years and millions of dollars to develop new therapeutics from scratch, large pharmaceutical companies sitting on huge piles of cash may prefer to buy innovative small/mid cap biotech companies to build out their pipelines.”
Since November 8th, IPIX has only increased the OS by 42,212 shares of common stock. That is 21,106 per month over last two months.
Prior to that was much much more.
I have a good feeling with trials ending and data being released there will never be a need for Aspire dilution in the future.
Think about all the data releases and PR’s since Nov 8th!!! There have been 8 releases........You would think that Leo used Aspire during those PR days, but it sure does look like that is false. Everything is tight at IPIX.
I got that feeling.
7,501,224 owned by Arudas on 4/28/17 which was 5.82% of OS which was 128,887,010 total OS
7,316,824 today. 5.22% of OS = 140,169,042 OS
The 10-K in November said they had 140,126,830 OS
Sooooooo since November, iPIX has diluted 42,212 shares
Hmmmmmmmmm.....and I can't buy shares on the ask. ?
Weird
Or you set "anchors". They are setting a few
Huh? Literally dumber....from reading that. What does IPIX bring? They have and own all patents to compounds. They have done years of research and have funded through multiple clinical trials.....millions of dollars. They have highly intellectual scientists employeed.
IPIX can run a phase 3 for BOM and Prurisol, we just need funds if they do not want to dilute or give up ownership.
That’s what BP pays for. Science.
Read the article on fierce bio today. The big wigs at BP say SCIENCE trumps all and brings innovation. There is no worry for small bio who have real solid science.
You underestimate Dr B’s relationships. IMO. We shall see who is on the right side in the next year imo.
I keep track of shares since I invested my first dollar here in 2012. There was zero financing agreement, they had zero trials in the clinic, just K and P in preclinical They had about 70K in cash or maybe less..... and 93million shares outstanding.
Wow how time flies.
We have another 30 million financing deal with Aspire. Where Leo controls the throttle. We have a 75 mil shelf.
We have completed 6 human trials. 2 are almost done, so 8 trials!!! We gained polymedix and drugs. We are around 140 mil OS now and at the same share price as 2012 ......
Did I mention we have passed every trial to date with flying colors? Not one failure. Yet we are valued by the market as the same as 2012. Where we had zero cash. Zero financing and zero drugs in the clinic?
I’m pretty sure poly was valued in the 200 million range prior to collapse.
I think the market will wake up here
Hahahaaaa!!! Every time someone claims Aruda is dumping....post the 13G. I don’t think a 13g is even necessary just like the last. They are under 5%???
Thank you. Very much.
LBK - had a great post a while back with actual numbers for IPIX if they partnered for B-OM and took the market share for SOM in prevention.
If the share structure stayed in tact from here.
What is the current market multiplier for value?
Every $5 is a billion in MC -
Say B-OM made 1 billion on the nose. Hypothetically what should the value of the share price be if IPIX took all 1 billion? Without any other drugs.
This entire conversation today is completely outlandish. IMO
The idea that IPIX is only worth 100-200% on a buyout is absurd.
Here is a little hint on how things move:
1) Acquire or Develop a compound
2) Raise funds to further develop the compound
3) Raise funds for pre-clinical testing
4) Based on results - Raise funds to take the drug into the clinic
5) Raise more funds to pay your company and third parties to continue to test and develop said drug.
6) Keep raising funds if you see more and more positive results, because the company has to move forward and to the next phase and present at the next showcase etc...
7) Keep raising funds
At some point there is validation and a ton of cash that is thrown at the company if the drug proves out. When this happens.
THE SHARE PRICE RISES! It's not hard to understand. There is no more reason for the company to raise funds through stock, so what happens? The share price rises!
We are waiting for that point.
The X factor between IPIX and many other bio's is that IPIX has 3 potential blockbuster drugs and we know currently that 2 of those compounds have multiple blockbuster indications.
There is no way that IPIX is sold any time soon. The validation must come first to increase our share price, and then every move that is made and every result that is documented the share price rises even more and more and more and more and more because IPIX is off the OTCBB and has INSTITUTIONAL SUPPORT by being on the NASDAQ and IPIX has an injection of cash from partners and support from partners to help expedite everything. At that point and when they get to phase 3 in many of the indications, a full buyout could potentially happen IMO - and by that time we are looking at 6-80-100 dollars a share price ---- so the buyout YES could be 100-200% the share price. Maybe 160, 180 200? That is when a buyout occurs.
There will be no buyout at this point for $5 or whatever is being thrown out around here.
Go look back at the major success stories starting out in the OTCBB - .55 to 1.60 to 3.00 to .80 to 4.60 to 14.80 to 33.80 to 68.00 to 101 to 211 buyout.
That happens over a 9 year span and the major take off occurs over the final 2-3 years...
WE ARE SO CLOSE IMO -------- the first domino will fall sooon!!!! IMO
I filled finally!!! 7K more boys. Locked up. No sale until Leo sells.
Because there is a difference in value by data. We show good data, we make more. Is that hard to understand?
For example, if Prurisol phase 2b data uses the same scale and criteria that Otezla used...and we show greater than 30% PASI 75...and show good safety then we know we get more money than if Leo just took a 100 bucks for the drug.
Data is what delivers money.
Later phase trials deliver more money.
It’s pretty elementary.
So we drip and wait
I did not have AON checked. That’s why I was surprised they didn’t tag me for like 10 shares at end of day for their 4 dollar fee. Lol
It was strange. But it happens often here for me. I’ll just put a buy at .75 this morning.
It’s a constant ASPIRE drip.
It’s an unknown -NO analyst coverage stock
It’s an iHub stock
I’ve played the pennies, the otcbb the pinks etc..... financial pressure always rules the day and that is where you find the most undervalued bargain stocks .... during times of raising money.
Leo has decided to go the long term responsible drip way. No huge CDs or other extreme toxic route, he has slowly milked over 40 million in shares into the market over the past 6 years. And believe me....to pay for 8 human trials and pick up 10 additional compounds is unheard of for only 40 plus million shares.
Nonetheless, it’s a constant pressure.
The minute we get validation and a deal this will re-evaluate in a flash.
Leo will only license IMO. ATLEAST first. The value of the company is no where near true value.
Everything will change in a blink soon enough.
Imo
The stock should be well over a billion MC at this date. Too many drugs too many trials too many good data sets. The market will agree once a major outlet confirms. The investment community are lemmings. Follow one follow all....lol
Keep up the science IPIX. The rest will follow one day
I attempted to buy at .73 this afternoon. 7K and it would not let me. However many trades occurred below at .7139. So freakin weird. Can we please leave the otc? I’m ready.
Pound the table! Great insight. No one at IPIX is feeling any heat or pressure to sell or partner for anything less than they want. IMO.
Read the PRs and you will understand that BP knows that Mgmt know just how valuable their pipeline is.
I tried buying more at the ask and could not get filled in the last 10 min even though it closed 2 cents below my ask. Crazy stuff
I love the Prurisol phase 2a data. It’s funny, I bet that this trial and results spark an epic run while everyone is dogging it and saying it’s so bad.
Really good post. The market will understand when its printed and confirmed in the phase 2b data. Peeps like Infiniti need apple to apple tests to understand.
He shall have it
Honestly. What is with the 59%? Go through your past week or two. 59% has occurred on more than 3-4 times.
Check. Awesome snippets from the companies mouth
I’m talking about investment community Bunhun. And no one has unless They read the mako hack dribblings. So I think I am correct.
BP has absolutely heard of IPIX and it absolutely takes many months to years to iron out deals especially when bringing in more than one Party which IMO is the case here. Also the final data is always needed. We are just about there.
No deal was going to be done prior to this late stage data. Leo has always said. Maximize value. You don’t get that in phase 1.
Keep trying. Not sure why you stick around. But for your families sake please do....
There is a major difference that puts K ahead...I’m trying to find the email from the company but I think it was to my old work email.
There is not much data out on the web for the MoA to decipher on my own.
It may have to do with mutant and wild type p53.
Just bought 5100 more. Waiting on 7000 to Clear for more. I’ll take it
Something is not right - I agree. That is for a separate discussion. I'm not going to go that route because I'm a firm believer there are some hedge funds that have some illegal holdings in a heavy short way here. My beliefs are my own and I have my reasoning. However a constant drip from Aspire does not help anyone, but it does buy us time and does move us forward. I mean you can't argue Dunn. They have used aspire to complete 8 trials. Mid trials and all have been successful ----- just one left in Prurisol and read outs are weeks away.
The data and the fact the FDA has allowed us to plan and move forward should have this stock over a billion MC.... IMO. Easily.
I think there are so many options outside Aspire to move a phase 3 forward. But I'm also thinking we are over a year in the making of a mega deal and deals take years.... I personally think iPIX has climbed the wall and sits on top .............we just need that one domino to fall and this will be a watershed moment in iPIX history. As I look at the history of companies and the movement of single drugs and single indications and share price increases and the huge gaps on single drugs....iPIX will gap more than anyone has ever seen IMO after the first domino falls. It's time to catch up IMO.
Good luck
Right. But when you read this board day in and day out it’s just crazy how the mood here could make people feel like....”OMG!!! .7238 cents —-ohhhhhhhhh they need to partner now and just take 2 dollars or a cup of lemonade for the whole company”
It’s just absurd here.
The value will be reassessed in the near future. It’s the market and many times it just happens overnight. IMO.
It is amazing how the mood here has been set by several that IPIX MGMT is in any sort of desperate situation based off share price. The word "begging" has been thrown around and the idea that IPIX 'NEEDS' to take a deal, just to take a deal...It is the most absurd idea and furthest from the truth.
For new investors or readers on this site looking into IPIX, do your DD on IPIX website and reach out to the company if you have questions.
Here is a little Sunday morning DAUB opinion:
The share price is at a low and for reasoning that can be discussed in a completely separate post. This is a highly unknown Bio Tech and resides on the OTCBB lacking major institutional buyers.
Here are some scenario's.
IPIX has 3 major drugs! Each of those drugs have several multi-billion indications opportunities. Each of those drugs are in mid-late stage clinical trials. The share price is at an extreme low for the pipeline and progress. For example, having B-Absssi (1 Day IV) sitting at a phase 3 start where that drug proved to be just as effective as Dapto (7 day IV) should warrant the current market cap and most likely have a higher market cap just for B-Absssi. IMO Dapto pulls in over a billion dollars a year.
Lets add B-OM where we just received extremely promising data for a phase 2 trial where this currently NO approved preventative SOM drugs on the market and the market is estimated to be anywhere from 1 - 2 BILLION dollars. Again there are NO current preventative SOM drugs. That alone should spur a several hundred million market cap as we secure a possible BREAKTHROUGH DESIGNATION in the upcoming months and secure our first partnerships.
Don't forget about B-UP/UC - this market is one of the most lucrative for IPIX as they add oral formulation for Crohns and UC. The data from the B-OM data just anchors this UP foam/water enema which alone could bring in 100's of thousands alone. Add different formulations and we are in the multi billions easily. IMO.
Not to mention Prurisol the dark horse, for Psoriasis. An ORAL drug for Psoriasis that has now completed it's phase 2b trial using the same criteria that Otezla did using the PASI scale. Remember OTEZLA is a blockbuster with major side effects and limited efficacy. The bar is set atleast - like 32% PASI 75. That is what we are looking for. I say lets go get 40% PASI 75 and this company should hold atleast a 5 billion market cap over night. IMO If the dark horse is proves even better, watch out BIOLOGICS ----- Psoriasis is close to a 10 BILLION market.
Kevetrin is why most of us arrived here. Years ago it was all speculative that CTIX/IPIX had a drug that could potentially reactivate the P53 gene - both wild-type and mutant. TP53 gene is the "HOLY GRAIL" of the human genome scientist say. They also say that it is affected in more than 50% of all cancers. The development has been steady and the phase 1 trial was extremely successful however it took a very long time to complete because Kevetrin was just too safe and they could not reach an MTD. Going from 10mg/m2 to 750mg/m2 took several years until they just decided to end the trial as the curve IPIX saw showed there was not much more benefit from that high of a dose. The fact that they saw p21 expression in the phase 1 and it was safe and they actually saw tumors disappear is a milestone and result that has been swept under the rug for I-Hub investors as the noise is much louder here. BP steps in and advises IPIX to go a different route in a phase 2a for Ovarian Cancer looking for more proof of modulation and MOA - and we just read the first data read outs for the first couple patients and they saw exactly what they were looking for. That alone - minus all other drugs and progress should give us a 5X market cap from where are on speculation that we could have the most sought after Cancer drug in the history of drugs. IMO>
But again, we are an OTCBB where 99% of the world has never heard of IPIX. The only people that know about IPIX are day traders and some small retail investors that read iHUB ----
IPIX does not need to beg for anything. They have "MULTIPLE CDA's" for all drugs. As they have said, some BP's are looking at one drug, some BP's are looking at all drugs, etc... The minute one BP sleeps or drags their feet is an opportunity for another BP to capitalize on these highly effective drugs. The potential here is 10's upon 10's of BILLIONS of dollars and the market cap will reflect that just like other major Bio's.
I went back and read a board for a major Bio that was bought out in 2015 and read the board going back to 2007 and looked at the price and comments over that span and what the company was achieving and compared to us here. I am in awe at our share price, however just like them going from like .55 to 261 and being bought for 21 Billion dollars, I believe our pipeline by far trumps anything close to theirs.
Over the next years, I think we will see the movement they saw going quickly from cents to 10 - 40 - 90 - dollars.
Again - there is no need for begging from anyone here at IPIX --- we are in the best shape we have ever been. We have Aspire and about 28million in financing and a 75 million shelf to raise funds if needed to go alone a drug or two. However, as LEO has stated, last years focus was partnership and they are close and in late stage negotiations so I assume we will put Aspire on the shelf at some point this year and many will need to cover their short positions as we wake up to a watershed moment where people will be out millions of dollars as IPIX's value is reassessed and the true value is unlocked. IMO
Lets go JAGS! and IPIX
That’s biotech though Dunn. Look at that Onxeo and validive deal. That sat for years after a phase 2 completion until last September where Monopar Therapeutics licensed it and moved it to phase 3. Or maybe it was soligenix. I can’t recall - but one sat on the shelf for 2 years.
The good thing. There is zero debt and we have plenty of capital that can be raised. We still have Prurisol data, Kevetrin data, and B-OM final report to allow FDA BTD submission in the near term.
I expect a deal for something this year. I will be extremely disappointed if that is not the case.
Oral K may spark it all...who knows.
IMO.
I know we have discussed this but if one simply plugged in standard SOM rates of 70-80% for HN patients the numbers for B-OM are off the charts, the 38% is obviously a huge winner and now seeing the secondary data showing the very few patients that did get SOM on B, they did not come down with SOM for about 10-14 days later and that much closer to end of C/R treatment which is a big win for B-OM as well.
I just think: how do you know these patients actually swished for 1 full minute per protocol? How do you know if one barely swished B around the mouth? Etc.... so much room for error imo.
Someone shake the machine!!!!
It has to be broke. 59%. 1/2 1/3 and 1/4
Close of .7397?
Is this real? Was it not 59% uesterday
I am making a purchase next week, so please take her down ;)
Life is much more pleasant here:
“Maybe I should just focus on the 4 year old nephew explanation on KM curve and pancakes instead :) “
Thanks for all the detail and discussion. I find it fascinating and brain swelling.
Agree. This stock should be no where near this price range...I’d pay 5-7 dollars for this pipeline today. It’s time to get noticed by a new audience.
Biotech and JP are always good fun!