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Damn placebos will do it every time!
AtonewithPPHM
We have a history of testing in hemorrhagic fever deceases. Recall we tested guinea pigs with lassa fever. The entire control group died while 50% of the bavi treated survived and after several months were reinfected with double the dose of lassa fever and were immune! Exciting times indeed!
AtonewithPPHM
Lung Cancer conference July 31-Aug 2 Jeff Hutchins presenter
AtonewithPPHM
Bio, Thank you for compiling this post. I noticed in the last quote by Joe Shan:
Quote:
Starting with breast cancer, we’ve now generated data from three separate clinical trials combining bavituximab with taxane chemotherapy. The most recent is from an investigator sponsored trial or IST by Dr. Alison Stopeck of the University of Arizona Cancer Center, in Tucson in which she previously reported an 85% response rate including a 15% complete response rate in patients with HER2-negative metastatic breast cancer.
Given these results in which approximately half of the patients were triple negative and extremely difficult to treat disease and the immune-stimulatory synergies that exist between bavituximab and taxane, breast cancer is high on our list of next indications. We look forward to the publication of final data in a manuscript form from this trial from Doctor Stopeck in the near future.
I wonder why he said, "previously reported". Have the numbers changed? Could they have changed for the better? Remember the statement from Dr. Stopeck, "prolonged immune responses"
Makes me go Hmmmm.
AtonewithPPHM
Yervoy/Bavi trial started on April 23rd. The protocol was biopsy and blood work at start, 3 weeks in more testing and at the 15 week mark more testing.
We are now 2 1/2 weeks shy of the 15 week mark. If some patients were dosed at the 4/23 start date we will start to get an idea of what is happening with more data following on each new patient as they cycle.
Based of Dr. Brekken's comments, "as much as 200-300% improvement in response" things should get very interesting and probably soon.
Any company with a SOC drug in use is in danger of being bumped by a competitor using Bavi or being guaranteed their position with the addition of Bavi. Not a hard choice in my opinion!
Strong Buy/Buying Opportunity! IMHO
AtonewithPPHM
Not a question of if but when!
Not a question of how much but "Holy Cow" that much!!
Patience.
AtonewithPPHM
If you hold and don't let go of any shares, heck, dare I say it, buy, I got the feeling that everyone is going to be in a much better mood soon!
AtonewithPPHM
"And the beatings will continue until morale gets better around here".
AtonewithPPHM
Bio I agree 100% I enjoy your posts. Thank you for all your DD. Your connecting of dots is why I keep adding. (Oops, am I allowed to say that?) Is there such a thing as an "Uber Strong Buy"? If not, I am starting one.
AtonewithPPHM
Dr. Stopeck, "prolonged immune responses" I wonder what that come mean? ;)
AtonewithPPHM
Funny guys! It's too quiet. Nothing can be happening! Ha Ha! Thanks for your input guys. I am sure glad I added another 10% today.
Let me repeat in the loudest possible way, BUYING OPPORTUNITY!
AtonewithPPHM
Also could be hours, minutes! Wake up and smell the coffee!
AtonewithPPHM
Paul, Good thinking! I added 10% to mine today!
AtonewithPPHM
In the conference call "manuscript due out soon" was stated. I said, "Any day now", I don't see a difference. Do You?
AtonewithPPHM
Wait till we get an update on the breast cancer trial results. I wonder what Dr Stopeck will say about the 15% complete remissions? Remember this statement "prolonged immune responses". I do! Manuscript due any day now.
ATonewithPPHM
Also, we have a backlog of 26 mil to 2016.
AtonewithPPHM
The sky is falling, the sky is falling! No wait, only down a penny! Someone sure got taken today! Better buy and hold at this point.
AtonewithPPHM
Got that right!! The fuse is lit. Positions are surely being taken. This is indeed a
"BUYING OPPORTUNITY!"!
AtonewithPPHM
Read this quote and then tell us again that they have nothing to report!
"Based on the encouraging results observed in this trial, including both a favourable safety profile as well as prolonged clinical responses, I believe that additional clinical development is warranted in this indication".
AtonewithPPHM
Semper, It seems that they down played the site number in the CC. You would think if they wanted to draw attention to the company they would have shouted 108 SITES! I believe they are getting a lot of attention/offers and that they are sitting on something big and they know it. And now I think we know it!
AtonewithPPHM
SK just said they were thinking carefully about expansion and where it should be. They option 11,000 sq ft where they are now. Does this mean a possible larger location somewhere else? I think so! And I think we all know why!
Atone
Man! I always have to laugh when someone tries to get into PPHM for a penny or two less. I would be afraid to hold out for a few cents and miss the runup. Do you realize that 1 cent on even 1000 shares is only $10?? Think about it.
Atone
Way too quiet. I feel it coming! Getting all tingly all over! SOON!
AtonewithPPHM
djohn, Imagine a snowball rolling down a hill. Start point was year one. Year ten is at the bottom. The snowball starts out slow and increases speed and size each year to where we are now. We are moving faster and growing in applications month by month. I believe we are at the finish line!! Hang in there!
Atone
Decided to add again today! Thank you all for the DD posted. You guys are amazing! I am more excited with each passing day. Not a matter of if but when and how wild the number will be!
AtonewithPPHM
Atone feels sorry for those who gave up 3 million + shares today! What were you thinking??
AtonewithPPHM
Atone is here, long and strong, and watching very closely! I have been very busy lately but I smell a deal coming soon! How soon? My real estate agent keeps asking me the same question!
I am planning to buy a second home on the west coast of Florida as soon as we soar. Also, I can't decide which new luxury car I want? Decisions, decisions, must be the same with PPHM. So many suitors!
Thanks for asking Wook!
I feel giddy,
Oh so giddy
It's so witty, how giddy I FEEL!
We'll be soaring and this time it really will be for real!
Atone,
Loaded up, buckled in and sleeping easy.
Geo, What a great analogy!! Only one thing, you are using a 10X multiple I believe that to be a 50x + multiple! We are clearly on the same page though.
Regards,
AtonewithPPHM
Hypi, Congratulations! You got it right in the last paragraph of your post. There may be hope for you yet. Have a great day!!
AtonewithPPHM
Geo,
I disagree. I don't think that a public company can hold back material events to effect cases. There would be a negative effect on current and potential investors if that were the case and they/we have rights too! Respectfully
AtonewithPPHM
Jim, Congratulations again! I am buying regularly without care of an up or down 10-20c move. We are about to explode! No doubt in my mind. I now need less of a move in SP to reach my happy number then before. God Bless America!!
Atone
zare2, makes perfect sense to me. There is a ton of news we could publish but aren't at this time. The more we accumulate during this period the less the sp has to move to secure our futures. Doesn't everyone get that?
Atone
Spanky, Been doing just that! Don't know exactly when, but do believe a major move is coming!!
AtonewithPPHM
Jim,
I have been adding on this weakness. Great opportunity! I know you add monthly. I believe in that system. Good luck to us all!
AtonewithPPHM
"VACCINE" CP, Bio, Sunstar, help me out here. Am I over reading this? I have the utmost respect for your opinions. I recommend that everyone watch Dr Brekken's presentation in its entirety but pay close attention between 29.06-32-36! Particularly between 30.22-31.14! Can anyone say VACCINE. Here is the link.
Jim, Holy Moly! What do we do? Does trafico think we should all sell?
AtonewithPPHM
Thanks IFU
Atone
Anything on abstracts? Thanks in advance
Atone
Jim, Isn't that the truth!!
Atone