Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
Bungler, so could you please explain how a common shareholder can come up with that kind of money to purchase shares ?
Biopharm, I believe in Bavi and that it works. I have also been in this stock for 13 years and have attended 6 shareholder meetings. If you go to one you will realize that at the max there are 30 people in the room including PPHM employees. The BOD is a joke with a couple of lawyers and bankers sitting up there looking pretty without having anything to say except that we are talking with potential partners for the last ten years. There is not a single MD on the board. There used to be an old neurologist for a year or two that passed away and was not replaced. In a nut shell this company has a clueless board that runs things and does not want to give anything away in order to be able to move the important stuff ahead. As someone said, they are hanging on to everything and hoping a miracle to happen so that they can make money from everything. I was in biotech business for 20 years and know that such a BOD without any industry talent on it with a CEO with masters degree is not going to get respect and will be bleed to death by the big boys. Sorry for the long speech. Time for me to go out and chill out :)
Entdoc, thanks for the encouraging words. I make sure that I leave a letter for my great grandchildren decades from now so that they keep the shares until the big day arrives :)
Bipharm, with all do respect I used to appreciate your posts but now it seems to be all "pie in the sky"
CP, Thanks for the response. Having been around for 13 years I am getting the feeling that the BOD is more into taking it all and not willing to give much. I think at some point PPHM should think about letting some or parts of the goods (ie cotara, imaging, viral) go in order to keep and develope the main one. Genentech (TPA) and IDEC (Rituxan) did and at end ended up doing very well for the patients and the shareholders
CP you seem to be a very logical man. Can you tell us with all these positive things about Cotara why can't the company find a partner for it after all this time. They can give 80% of the royalties away and still be able to cover all their Bavi trials with the money that they will get for it.
1st line MOS question: does anybody know what the current MOS for the SOC in 1st line NSCLC is ? thanks in advance
Phage/manufacturing: I don't know where you guys came up with "phage". A friend of mine set up a manufacturing facility called Peregrine with water purification system in sorrento valley where all the Biotech and BPs are. When we were talking about PPHM he thought that was the company but after checking his files he realized that it was a microchip company called Peregrine. I did not realize that microchip companies need purified water so in a earlier post I clarified it and apologized to the Board
BioChica, Regarding ASCO, 11 out of 13 evaluable breast cancer patients showing objective response with 2 complete responses doesn't sound exciting to you ?
Manufacturing Correction: The manufacturing company in Sorrento Valley that I talked about is a microchip manufacturer called Peregrine. I had no idea that they use purified water too and that is what got me confused. Sorry
Don't have the time right now to do the research but if Cook is located in Sorrento Valley then PPHM was probably helping them to improve their manufacturing processes. And if Cook is not located there then there was something else going on! Avid is not in Sorrento Valley. Got to go guys
jimsgtx please read my last post. I think it is another piece of the puzzle that we are trying to solve. Have to go now. Happy weekend to all.
It is a fact and that is all I can say. Sure you understand.
I thought PPHM working on a manufacturing facility 80 miles away from Avid in the biotech/pharma country was an interesting news but I guess you people didn't dig it ! Lets talk about how good Bavi is for the Million't time :)
iHub detectives/researchers : PPHM was working on a manufacturing facility in Sorrento valley late last year. Sorrento valley is in a part of San Diego county where all the bio/pharmas are including Pfizer with a big facility. It is about 80 miles South of Peregrine. Can anybody figure or guess what that means ? Of course the above is my guess. wink wink :)
Thanks a lot biopharm. EOM
Breast cancer question: will they be able to report more updated results at the last minute at ASCO if there is any available from the last 4 patients or do they have to stick to the results that they reported in the abstract ?
Breast cancer question: will they be able to report more updated results at the last minute if there is any available from the last 4 patients or do they have to stick to the results that they reported in the abstract ?
My comments apply to any BP that might be interested in PPHM's science and not just Pfizer. Lets hope our management don't give away the company to become very rich overnight and move on.
PS: take this from someone that went through IDEC's two stock splits one was 3 for 1 and the onther was 2 for 1 only because they partnered with Genentech for Rituxan.
If it is Pfizer: We all better hope that Pfizer becomes a partner and not the owner of PPHM. If owner, we are going to miss on a lot of splits and for some of us big share holders millions of dollars.
Quick trial: the strategy would be to arrange for an independent review committee to look at the interim data(may be even unblinded to them) and if they see drastic results such as half of the patients are dead after lets say seven months and the rest are still alive and doing well, then it would be unethical to keep the remaining patients on placebo and to let them die.
swg tdr thanks. Lets hope all the little bits of data that we get from all the ongoing Bavi studies proves Bavi's overall MOA.
exwannabe thanks. It is starting to make much more sense to me. Thank you all for the info. Have a good day everybody.
md125 thanks. I guess the part that I don't understand is when a pt leaves the PPHM study because of treatment not working and since it is their 1st line of cancer treatment moves on to other studies or treatments outside of pphm involvement, how does PPHM track that patient's progress and how can you tell if Bavi had any role in their extention of life while being on other treatments outside of pphm Protocol. Anyway, thanks for the response. Have to go to a mother's day party. May be a couple of drinks over there will clarify things for me.
Thanks md1225. Not knowing the details of the protocol and whether it has a maintenance part for respondents to continue. My thinking with regards to what you are saying is that if the treatment didn't work during 1st line and the pt comes off, why would they want to continue with Bavi for 2nd line and if they go on to other studies and treatments, how can PPHM follow up on their status easily from other studies or treatments. And I don't know if this is an international study which makes it even harder to keep up with the pts information.
ImaPseudonym Thanks for response EOM.
Question regarding 1st ln: As far as MOS measurement goes, if a pt comes off the pphm study for any reason including progression and ends up in a 2nd line or 3rd line studies how can the Overall survival of that patient be associated with Bavi study and measured? Any clarification is appreciated.
waited for 2 1/2 hours to get filled at 1.39 and didn't happen. Moved it up to 1.40 and went through in 2 minutes for 14000 shares
Question: If the FDA asks PPHM to redo the study would that be considered a material event and needs to be PR'd immediately?
Stoneroad, if you have been here for ten years you should be able to notice by now how this drug we know as Bavi is advancing it's way through the drug development process with good results.
Job Posting: to me it means that they realized the potential of Bavi for many indications and imaging and have decided that they don't want to give the whole thing to one BP. They need such a person to break this down to many indications and geographical licenses.
ImaPseudonym thanks for the response I have a feeling we are going to be very pleased with the 1st line results.
Please don't ask where I got it just analyze it based on your MOS uderstanding and let me know if it makes sense
MOS for 1st line NSCLC question for the brains on this board: what does it mean if I told you that the MOS is not reached and there are still two patients receiving treatments ? Does this statement make sense based on the information we have for the dates and MOS criteria so far.
Is it possible that PPHM is requesting or planning to request a BTD for 1st line NSCLC based on the data that they are seeing internally.
No, what is going on here is great science and a great drug as a result of that science but a couple of low level bankers and lawyers that have no clue how to run a biotech trying to get it to market. I wouldn't be surprised if they are Pis###g off all the consultants and advisors with their decisions. Have a good one all.
EYEBUYSTOX, would you be nice enough to send this to PPHM IR. Thanks
Right on Sunstar EOM
I think all the traders should give this board and the old timers (10 years an over)a break tonight to mourn a good human being. we can talk about your market knowledge and how much money you make tomorrow. Thanks