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WILDHORSES...
Is it you coming in and buying AVID?
Posted by: Wildhorses
In reply to: realist1 who wrote msg# 23166 Date:5/8/2008 8:42:31 PM
Post #of 23594
Realist........
I can't believe I read one of your posts - I must be bored. But, since I did, if I told you I could/would provide the boys with $75 million in financing to see them through the forseeable future, would your analysis remain the same?
Thanks in advance for your prescient and thoughtful analysis.
Regards,
Realistic Realist
BOT...
Hope they all come to fruition because the clock is ticking!
pphmlover...
Big news coming swiftly or rapidly is next. Whatever that means???
Where is Big On Tarvey... & SP...
though not in same ballpark on predictions. Bot have disappeared on us? Come on BOT. SP. Insights please.
HELP... wife threatens me twice a week now. Much more and am going to start wearing a jock strap and titanium cup to bed.
Maybe all the time!!!???
Cj...
I had May 30 down for the date also but then did not see it on the website.
Oh well, back to May 30, but can a company still get added all the way up to June 27? Reads as if so?
Long way to go for PPer, but gotta keep hope alive since all I got.
Jake... Russell
Looks like more than 10 trading days to me. Hope PPer has something good to release before June 13.
June 13 Preliminary additions and deletions to the Russell Global Index and the Russell 3000® published
June 20 and 27 Updates to the list of additions and deletions
June 27 Reconstitution final after the close of the U.S. markets
June 30 Final membership lists posted for the Russell Global Index, Russell 3000®, Russell 1000®, Russell 2000®, Russell Midcap® and the Russell Microcap® indexes
Q: When is reconstitution this year?
A: The 2008 reconstitution of the Russell Indexes will occur June 27. Both our U.S. and Global index families will go through reconstitution simultaneously.
Provisional indexes will be published beginning on June 13 to allow investors to begin to track the new indexes prior to reconstitution and legacy indexes will be published beginning on June 27 to allow investors to continue to track the old indexes.
We provide these indexes before and after the official reconstitution date to allow investors to choose their own timing on when they want to execute their index trades.
http://www.russell.com/indexes/membership/reconstitution/default.asp
Ooops... thought this was new
data with the healthier patients. Excuse my dumbassness.
Imagine what Bavi will do with Stage I patients.
Bavi sounds good for Stage 4 cancer...
I tought these were healthier patients??? All were Stage IV!
50% of all evaluable pts achieved an objective tumor response or stable disease. These findings warrant further efficacy studies of B (Bavi) in pts with refractory solid tumors.
Some GOOGLING Info...
When the decrease in tumor size is used to evaluate the therapeutic effectiveness of a promising anticancer agent in a short-term clinical trial, it is considered to reflect objective response to therapy.
Overall Stage Grouping is also referred to as Roman Numeral Staging. This system uses numerals I, II, III, and IV (plus the 0) to describe the progression of cancer.
Stage 0 carcinoma in situ.
Stage I cancers are localized to one part of the body.
Stage II cancers are locally advanced, as are Stage III cancers. Whether a cancer is designated as Stage II or Stage III can depend on the specific type of cancer; for example, in Hodgkin's Disease, Stage II indicates affected lymph nodes on only one side of the diaphragm, whereas Stage III indicates affected lymph nodes above and below the diaphragm. The specific criteria for Stages II and III therefore differ according to diagnosis.
Stage IV cancers have often metastasized, or spread to other organs or throughout the body.
Within the TNM system, a cancer may also be designated as recurrent, meaning that it has appeared again after being in remission or after all visible tumor has been eliminated. Recurrence can either be local, meaning that it appears in the same location as the original, or distant, meaning that it appears in a different part of the body.
Don't get your hopes up...
more mice data?
Slippery Pete....
Big news / event(s) coming "soon" or "shortly"?
Is there a difference?
News ETA please???
Spanky wife 'bout to cut Spanky nads off soon / shortly!!!
That will most likely hurt!!??
SP....
Is "shortly" an earlier date than "soon"?
Still waiting and waiting and waiting and waiting...
Rone....
Delisting is not end of May or beginning of June. Deadline is (I thin) July 22, to be at above $1.00 for 10 trading days. Plus they will try and get an extension, which may buy them 2 months. BUT is not end of MAY.
Stock Doc...
Who knows? I hope it is something new and good, no more mice data please.
If it is the same type data again it is because PPHM wants to keep all the good stuff "secret"... for now.
Wild Horses...
You gonna put the $75 Million into PPHM?
Start on May 22nd and build price up to say $1.30 by May 30th please. Keep us above $1.00 for two weeks.
Thank you.
Article...
do not know if really applies....
http://www.ajcn.org/cgi/content/abstract/87/5/1530
We'll take it... Wild
Horses. Bring it on, please. Hurry, though.
Pete...
PPHM is doing a most excellent job of keeping all the great science a secret.
Future here now Pete?
Posted by: slipperypete
In reply to: MobyInvestor who wrote msg# 20145 Date:1/4/2008 2:10:27 PM
Post #of 23054
The world does not know yet. This will soon change in the near future.
S.P.
PS: Been a lot of the above over the last 2 plus years.
I hope you really...
know something and are not just "pumpin". But afterall this is just a message board. I WILL BELIEVE it when I see it.
IF I SEE IT!!!
How SOON?
Slippery Pete...
I own enough shares that if this PPer does not do something GOOD, relatively soon, my wife is going to cut my B____S off. Been in over 2 years now.
Slippery....
How soon is soon?
Slippery Pete...
how long have you been saying this same type thing...
MY FRIEND YOU DON'T EVEN REALIZE THE RACE IS ALREADY OVER AND YOU HAVE LOST. LIKE I SAID. IF YOU ONLY KNEW.
Hope comes true but...
A Step Forward in Virology
A step forward in virology
Renata Cosby, Corporate Communications
Eidgenössische Technische Hochschule Zürich (ETH Zürich)
25.04.2008
Viruses use various tricks and disguises to invade cells. ETH Zurich researchers have now discovered yet another strategy used by viruses: the vaccinia virus disguises itself as cell waste, triggers the formation of evaginations in cells and is suspected to enter the cell interior before the immune defense even notices. The research results have been published in Science.
The vaccinia virus has a problem: it is a giant among viruses and needs a special strategy in order to infiltrate a cell and reproduce. Professor Ari Helenius and Postdoc Jason Mercer from ETH Zurich's Institute for Biochemistry have now discovered what this strategy is. In the process, they stumbled upon new and surprising findings.
The invasion strategy
In order to infiltrate a cell, the vaccinia virus exploits the cellular waste disposal mechanism. When a cell dies, other cells in the vicinity ingest the remains, without needing waste disposal experts such as macrophages. The cells recognize the waste via a special molecule, phosphatidylserine, which sits on the inner surface of the double membrane of cells. This special molecule is pushed out as soon as the cell dies and is broken into parts. The vaccinia virus itself also carries this official waste tag on its surface. "The substance accumulates on the shell of vaccinia viruses", Jason Mercer explained. The pathogen disguises itself as waste material and tricks cells into digesting it, just as they normally would with the remains of dead cells. As the immune response is simultaneously suppressed, the virus can be ingested as waste without being noticed.
The uptake into the cell itself is via macropinocytosis. The ETH Zurich researchers have demonstrated that the vaccinia virus moves along actin-rich filamentous extensions towards the cell. As soon as they impinge upon the cell membrane, an evagination forms, a bleb. The virus itself is the trigger for the formation of the evagination. Using a messenger substance to "knock on the door", the virus triggers a signaling chain reaction inside the cell so that the bleb forms, catches the virus and smuggles it into the cell.
Proteins as unsuspecting allies
"The viruses are the Trojan horses that want to enter Troy; the Trojans are the many proteins that transmit the signals and open the 'city gates' to the unwelcome guest", Ari Helenius said. Aided by Professor Lukas Pelkmans' team, Jason Mercer examined over 7000 different proteins in order to find out not only which Trojans let the virus in, but which as well are chiefly involved in the supply chain. Using definitive methods, the researchers de-activated each one of the suspected proteins to examine their function,and narrowed the vast number of proteins down to 140 potential culprits. The enzyme kinase PAK1 turned out to be an especially "helpful" citizen of Troy. Without PAK1, the pathogen's trick did not work and the cell did not form any evaginations.
Until now, very little has been known about the mechanism vaccinia viruses use to infiltrate a cell. Professor Helenius, whose research objective is to find out what methods and strategies various different viruses employ to invade somatic cells, clarified "This strategy is a new one". Other viruses, such as herpes, adeno and H1 viruses use macropinocytosis. However the vaccinia virus is the first one identified that uses apoptotic mimicry as an entry strategy.
Knowledge of the virus strategies and the signal proteins involved in the ingestion of a virus by a cell is crucial to finding and developing new agents against the pathogens. Until now, antiviral medication has targeted the virus itself. Ari Helenius, however, is looking for substances that interrupt the signaling chain and halt the communication between the virus and the cell. If the cell does not ingest a virus, the virus cannot reproduce and is quickly eliminated by the im-mune system. This process also has another big advantage: "Viruses cannot adapt to the obstruction of the signal chain all that quickly", he said.
further information:
ETH Zurich
Jason Mercer, Postdoctoral Fellow
Telephone +41 (0)44 632 58 18
jason.mercer@bc.biol.ethz.ch
I"d rather have "going concern"
than a PIPE just to avoid that clause.
Here is what I KNOW...
We are at 43 freakin cents, and everything "good" is always going to happen in the future.
Reverse Split....
Will not happen with PPHM... but ran across this info.
Revlon Tries Reverse Stock Split Game, And Gives Guidance (REV)
If you have followed shares of Revlon, Inc. (NYSE: REV), you already know what a long-term let down this stock has been. Despite years of having top models pedal its wares, it's stock has been a financial disaster.
Management has decided to play one of the oldest shell games on Wall Street. Its board of directors just announced a REVERSE STOCK SPLIT with a 1 for 10 ratio. So now 1,000 shares will become 100 shares. management called this an effort to appeal to a broader base of shareholders, comply with NYSE listing standards, and reduction in certain costs.
The company is also giving preliminary guidance. It sees set sales of approximately $320 million, compared to $328.6 million in the first quarter of 2007. First Call only shows one estimate and that was for $350 million. Other guidance is as follows:
Operating income of approximately $30 million, compared to $3 million reported in Q1-2007; Net loss of approximately $5 million, compared to a net loss of $35.2 million in Q1-2007;
Adjusted EBITDA of about $55 million, compared to $32.3 million in Q1-2007.
The company said that net sales in Q1-2007 benefited from the initial shipments related to its launch of Revlon Colorist haircolor, which was the primary driver of the change in net sales year-over-year. But Revlon is also discussing improvements this year as "significant improvement" in it preliminary operating income, as well as its net loss and its Adjusted EBITDA in Q1-2008.
Management also called 2007 one of its best years in many and that it has remained committed to generating profitable sales growth and positive free cash flow.
Shareholders don't really need to do much here as far as any action, because the Ron Perelman entity called MacAndrews & Forbes that has a combined Class A & B total voting power of 74% of the voting power has already approved the reverse split.
Revlon shares are now down about 6% on the news to $0.90 today. This will mark a new-52-week low as the prior range was $0.91 to $1.48. Five years ago, this was a $3 to $4 stock; and until early 2006 it had mostly traded in a range from $2.00 to $3.50. Shares used to trade exponentially higher than today.
Jon C. Ogg
April 11, 2008
http://www.247wallst.com/
Yo.. from Dublin
PPS is sweet... freakin eh. Where is the Duke Paper? Off to Madrid today. Last vacation, wife castrating me next month due to PPHM.
Somebody move the price please.... UP that is!!!!
I'll take VRTX's 52 low...
anyday in place of PPHM PPS.
now 3000 sh. @ .89?? eom
BOT...
thanks. Hope all of this gets us to at least a $1.00, eh.
Big On Tarvy...
Hearing anything good coming our way? TIA.
Vols #1
First time in history of 100 years of Men's basketball.
PPHM going up on this!!!
Fortune Cookie...
Can't tell you exactly what wife's fortune cookie said at Thai place we went to Sunday because she says if I tell anyone it will not come true.
Is paraphrasing ok? Hope so?
"Coming into a Fortune between between March 13 and 25th."
Keep those dates for news.
IF comes true the numbers on the back of the cookie are my new lottery ticket numbers by the way.
PPHM Tustin, get us >$1.00...
for 10 days to get this off our back. Number 1 priority!!!!
So far so good last week, keep it up!!!
$.50 or $.53... better get moving
to get our butt over $1.00 by early JULY for 10 straight trading days. That's 2 weeks.
PPHM LISTENING????
oops little behind the times
Form 4 filed by 7
PPHM Insiders...
Go PPHM in 2008....
PPHM time to deliver!!! Come on people!!!
Direct Registration System Question???
So how do we get the securities registered in my name? I trade through an electronic service.
The Board of Directors of Peregrine Pharmaceuticals, Inc. (the "Company") adopted certain amendments to Article V of the Company's Amended and Restated Bylaws (the "Bylaws") to clarify that the Company's outstanding securities may exist in either certificated or uncertificated form, and to make other revisions relating to that clarification.
The Direct Registration System allows investors to have securities registered in their names without the issuance of physical certificates and allows investors to electronically transfer securities to broker-dealers in order to effect transactions without the risks and delays associated with transferring physical certificates.
The amendment to Article V also provides that each registered stockholder shall be entitled to a stock certificate upon written request to the transfer agent or registrar of the Company.