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Lockdowns never hurt those who write these articles, only the rest of us. GO IPIX.
Has anyone here yet disputed that the SuperComputer was incorrect in its findings years back when they selected "B" as the wonder compound? Anyone here think that was now a keystroke error? Thanks for playing.
Assume a whistle was blown then as if he got up snd ran toward the Packers end zone snd scored would they call it a touchdown for Packers then? Or not?
Did I just witness the Packers intercept s pass from the Browns with one minute left and run it into the Browns end zone to celebrate and no Brown player touched the interceptor at all so is that not a Browns touchdown????
That does make one wonder if they are totally dependent on others to provide this information. All roads lead to Russian disinformation again in my mind. Cannot pay enough for this kind of disservice. You own what you paid for or maybe they can’t get it unless some other random is paid first who knows without any information.
Very true as other humans among us are attempting to create new viruses that are deadly to humankind. As long as those type of fools exist, hey let’s try this next, then there is hope for “B” to be a necessity. Go IPIX.
Not information we are entitled to comment tells you all you need to know about how good the overall reported information about PH2 testing completed was. This smells to me that IPIX was totally at the mercy of others as to the administering of their B to these patients and the results. It is bothersome that someone in our organization did not make the physician information data as a part of its use in this phase. Gosh almighty pretty poor negotiating skills here to me. Definitely not something that gives anyone a good feeling about what other details we never requested and never received. All this time going by gives those in real control how to manipulate this data to suit their own needs (Russia’s Needs) hint, hint. More for Putin here. Yeah Leo sorry your product failed because we say so kind of crazy going on here in my simple opinion. Big error in doing this with a Country s whose MO is to take great things from others snd show the world no we are the victim here not Leo. Meanwhile back at the ranch Russia probably is moving forward with B on their own as contracts or whatever document Leo signed is of no use in the wilds of Russia. Putin if you recall jailed the billionaire oilman and took all the company assets partly for his own wealth. Do not believe IPIX had any teeth in its Rousseau gentleman’s agreement here with B. I am almost certain Russia is continuing its testing of B with great results and maintaining that secrecy all the while telling everyone this failed miserably. I hope I am wrong but my intuition says I am not wrong. GLTA here. Rules mean nothing over there especially when now Russia can save the world with B. Thanks.
Keeping the data really close to the vest here, BP leaves them be for now due to subpar performance on phase II trial but make no mistake here folks that BP still knows the potential here no doubt in my mind. I think PR was red meat for those heavily invested here enough to keep you interested in the possibilities. Leo and team still know what they have. Other results from others could come at any time as well. Super computer selected this compound as the best at fighting this virus. I am still in that frame of mind and not going anywhere. As you can see I have been busy snd not able to post at all recently. Enjoy the holiday’s and families this is not a time to dwell on this stock/company. I for one am not worried here. GLTA here snd again thanks for all of your comments good and bad as we all have our say here.
Bria is in was chosen a long time ago by a Super Computer as the best possible compound to beat this and other viruses, and it’s 426 rating seems to be one reason as well that some clinical creation using such will eventually produce great results. Whether that means Leo sells this off or rents it off to others for a percentage or fee remains to be seen here. I am truly disappointed with the company as to regards to Del Grado with all of the accolades bestowed upon him and his credentials how did he not see this coming due to dosage or other restrictions or combinations they may have been unknowingly forced to use here for safety sake of these patients. I am also disappointed that the mild to moderate cases were not a part of this PHASE in testing. But again overall I do not doubt it has a medical need in the world based upon my earlier comments above plus why would military be interested if there is really nothing here as well as other institutes as it were, that costs IPIX zero other than supplying it out to those entities. I will hold down this fort if others wish to depart with their money. Thanks all.
Thanks we all need to step back and take a breath. Happy Holiday season all, I still expect great things to happen here so do not misinterpret my comments. Take it easy all.
Invest only what you can afford to lose here folks. Good news or bad we still may have some promise here time will tell once again. Meanwhile back on the real money farm BP marches on with their YS billions with a product that helps about 35% of folks. Wow they are so great snd we look like we suck badly. Go IPIX Go. Little train that coulda.
Good one. Agree almost 100%
Sure they are. Go ipix
loanranger, key words from your post, the Company said this following by all those nice little details. So loanranger, where is THIS?????????????????????? today????????????????????? OK they have had some time here now and of course using the real life data to fill in all those blanks they have stated. So what is that status of filling in those blanks? Anyone know here? Guess they are still working on it.
Excuses to use:
Still working on it.
We have to peer review our findings
We need to go out and buy more coffee
We'll get back to you in a week or two or three or maybe months.
We lost our signal
Our data is damaged but not all of it we are sorting through the positive details now, seems we lost the negative findings? Hmmm..
We cannot read Russian. Please send a decipher or translator please.
How do we convert millimeters to ounces?
Great News New CEO of Tweetle Dee and Tweetle Dumb is putting one of the final nails in the coffin of this non-productive non company. Nice love to see this fail and go out of business, most non-productive entity on earth next to Fakebook and Tic Tac. What a waste of time these all are. Go CEO put this under thanks. Go CEO put this where it belongs in the trash pile of strife creation. Thanks.
loanranger, I for one do not believe that the only benchmark they garnered from these results was deaths. Does not make any sense regardless of the directed dosage, if that is in fact true. Where is the data that states 90% recovered fully and left the hospital, or 75% got well and were able to leave the hospital with no other treatments? Or 25% became fully rid of this virus and walked out of the hospital under no further treatment. There must be other methods of measure here other than deaths. With x,y,z dosage (10) patients fully recovered from the (50) Patient's receiving Brilacidin. Something very simple here, why report deaths I do not believe that to be our only benchmark and why it was only addressed from their only PR here is mind boggling. Where is the good news from this study? Were theses patients also on other medication in case B failed so they would survive based on other measures taken to coincide with Brilacidin administration to them at the same time and their dosage? Basically where is the real data? Is it that Russia is keeping this all to themselves without divulging the real information truthfully to IPIX? What is going on with the real results here? Longs here deserve to get these answers. This is like saying well 1,000 kids bought bicycles in this Town and 10 of them died from using them? No word about the other 990 kids who bought them. This is what I liken this to. Missing 90% of the real information here.
Correct. Go IPIX…
So does Hydroxychloroquine for many years.
Does not prevent viral entry but spread. Thanks good stuff here. GO IPIX…
Amazing to me how we hand out hard earned taxpayer dollars to billionaire companies on products that do not work as advertised, yet for some unknown reason we have difficulty taking it back when the Merck’s of the world fail to deliver. We are truly one sick nation when our own people cannot steer this ship or right this wrong. It’s why we have strife in our nation, things like this debacle just add to it all.
GO IPIX….
Breaking News from Russia, just for those interested in such news items. Covid 19 vaccine Nasal Spray.
https://www.cnn.com/2021/11/24/europe/putin-nasal-spray-covid-19-vaccine-intl/index.html
If you all love to be hateful to others in the world then by all means join Fakebook, Tweeter Dee/Tweeter Dumb, Instacrap and Tic Tac. Go ahead make you day by ruining someone's life on these social media crapola forums. Good luck being human after that. No scruples, no brains, no common sense. Dumbness abounds on these platforms. I cannot even believe folks actually get their news from such nonsensical media outlets, too funny.
Then I guess those that fund creation of such deadly human viruses need to catch it first and we can be done with them all. Thank you MM.
GO IPIX.................
If you love strife in you're lives then you will love to use social media like this one and Fakebook, Instacrap, TicTac, and the others. Go ahead feel the full affect of strife in your lives or create some new strife in others lives that join such idiotic media outlets. Life is yours to lose so go ahead and join Tweeter Dee/Tweeter Dumb and learn about strife and how to create it in others lives.
Good article here on nasal and stronger viruses forthcoming. The article that I really want to read is that law enforcement is on the heels of those that create such viruses that affect human life as we know it and they are about to stop the spread of such virus creation and research and level these buildings to the ground. That is the article I want to read. And the lab scientist who create such viruses stand trial in the Court of Public Opinion at the Hague Court room and spend the rest of their lives in prison in some cold desolate place on earth. That is the article I want to read. Those who create and play with our lives with virus creation need to be gone from our earth.
My points below, thanks for the input here.
"Good points!"
When will the data from the complete analysis be available? My guess Feb 25, 2022. My guess is when the coffee pot is empty.
Who is doing it? An undergrad student? Marcus Welby, M.D. or Dr. Kildare.
Does B reduce the viral load in a clinical setting? Hmmm good question ... they'll redirect us to RBL lab results. "Only with Peanut Butter"
Why is the Company encouraged by compassionate use. Is it simply because they have the requests or are there positive outcomes in this setting? At this juncture LE's hoping for a miracle. Because we are compassionate people
Why the nebulous statements? There should be nothing to hide at this point.. someone had already mentioned SQUID GAME? (only one winner at this point- already made 5-8 millions in the last 10+ yrs?) "We got no money to pay for an advisor for our press releases so the 12 year old kid next door does them all he's a whiz and at $5 per hour well worth it.
After all these PHASE-2 trials data...we're heading back to run POC trials. We are heading to the Hawaiian Islands for some R&R from reading all these BS posts and spending all of your money, thanks.
loanranger, thank you it was taken from the October 25th PR portion below I took this incorrectly here.
"The Company is also pleased to report Brilacidin has been shipped to two academic laboratories for planned in vitro testing of Brilacidin in over 20 acutely infectious viruses, including Ebola, Marburg, Nipah, West Nile and Zika, through a collaboration with U.S. government scientists. The goal of this testing is to further inform the spectrum of Brilacidin’s antiviral properties."
Thanks again, GO IPIX.........
Not sure I follow this comment in this PR which I also believe they are attempting to stop some PPS bleeding here as well.
I had thought this was already ongoing from former PR's and statements not it is to Submit "B" for inclusion??? Anyone? Did everyone else think this was already going on or not?
the plan is to submit Brilacidin for inclusion in government-sponsored COVID-19 clinical trial platforms
GO IPIX..... I think
For those here actually interested in some new Vaccine news around the world, there is a lot going on with many others. These are but a few of those. GO IPIX get these full results released please. What was the delivery system and amount of drug used for best results or cautious results? Thank you Board for your support here.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159019/
https://emergexvaccines.com/
https://emergexvaccines.com/emergex-announces-approval-to-initiate-phase-i-clinical-trial-of-its-next-generation-covid-19-vaccine-candidate/
To me news of these latest test results mean something totally different to the company versus someone holding shares of stock. This testing gives the company and others data/information about "B" and its usefulness. It is not all bad news folks. Yes if you own shares it turned out bad but if you are a scientist it gives you new data points and knowledge, that is why folks do tests to start with. They all learned something from these results, stockholders learned how to get mad and run. But holding is not fault of those who have stayed. It is the hope that this Brilacidin will have its day in court and in the sun to help humanity with ailments not now being handled very well by these MRNA vax machines. I for one am sitting tight as I understand what tests do, they drive you to the area you need to go to they allow you to know what not to do and what to do, they give you hope as to the proper use of your drug and where it can benefit humans in our society. Hate gets you nothing but more hate. Try some patience versus MacDonald's syndrome. Thanks all stay the course good things will come here.
As a company putting together a PR with results I won't say good or bad as we don't know all those details yet, they should have sent out the Friday PR on the same day within the hour, that way trading would not have sunk so low unless they had some internal intentional reason for doing so. I did not find the first PR bad news as some here felt from reading it. Poorly worded I will give you that, so next time don't rush to put out something that simply read badly. Thanks all, GO IPIX and LONGS.........
Thank you JTFM love it here. Be safe out there. GO IPIX LONG and STRONG....
The first bold print why not share the counts of the data per patient count here? 40 of XYZ or 60 of ABC etc. etc. Puzzles me. Second bolden statement then why test patients in this difficult population/situation of this type of patient's to best see promising results the use of this Brilacidin? If you knew it was difficult to achieve said results? Baffles me. Third bolden why Leo do you compare yourself to these other two dolts if you feel what you own is far superior than them in all the related subject matter put out over all these months? Baffles me. There should be no comparison to these others. Fourth bolden comment about the antiviral aspects/prospects of Brilacidin via NIH and academic researchers? From where?
What of the US Government testing of Brilacidin against these other (20) different virus streams, why would they do so if they saw zero promise here folks? To me if these results are (4) dead of (40) or (60) in a severe condition from Covid and we know nothing of existing health conditions with those patients and for all we know IPIX knew nothing of those patient conditions either here. Alot of items are missing here folks, this is not the end to this story for sure. To me no improvement over a placebo this means it does not matter if you are deathly ill from Covid nothing will save you. I will say at this time we had a Co-Worker on a ventilator two weeks ago and on a Friday was put on it. His Doctor prescribed Ivermectin to be used on this person that day and by Monday morning he was sitting up in his bed eating food and no I don't know what that means except it happened. On that Friday they felt he had no chance of making it. Just saying.
The last bolden comments. Not sure what they mean by the normally 6.67% die from this patient population. Assuming over 58 plus years old and sever Covid symptoms. I guess. Again missing components of counts and numbers as to what they mean on a graph or chart would be nice you put out this PR and it to me is a big nothing burger, except you could not save severely ill Covid patients, that is it.
WAKEFIELD, MA / November 11, 2021 / ACCESSWIRE Innovation Pharmaceuticals (OTCQB:IPIX) (“the Company”), a clinical stage biopharmaceutical company, today reported topline results from the Company’s Phase 2 clinical trial of Brilacidin in hospitalized patients with moderate-to-severe COVID-19. Brilacidin is being developed for treatment of COVID-19 under FDA Fast Track designation.
Brilacidin did not show a difference compared to placebo in reducing Time to Sustained Recovery Through Day 29, the study’s primary endpoint based on clinical status. Clinical status endpoints contain a degree of subjectivity that may impact outcomes of COVID-19 trials. Additional analysis of topline and all study endpoints is ongoing.
“Though disappointed with these topline results, treating moderate-to-severe COVID-19 is an exceptionally difficult patient population,” said Leo Ehrlich, Chief Executive Officer at Innovation Pharmaceuticals. “Companies, such as Merck and Regeneron, also did not show clinical benefit in these groups of patients, although both went on to refocus their development efforts in mild-to-moderate COVID-19 and achieve success. Regarding our Brilacidin antiviral program in general, collaborations with NIH scientists and academic researchers to explore Brilacidin’s broad-spectrum antiviral activity in different viruses are ongoing. Initial feasibility work to formulate Brilacidin for potential prophylactic use via inhaled delivery, to leverage Brilacidin’s unique virucidal and blocking antiviral properties, also is underway. There are many paths to pursue in the antiviral space. We believe Brilacidin holds tremendous promise as a differentiated antiviral drug candidate and plan to continue its development in this area of great opportunity and unmet need.”
Topline safety data showed Brilacidin was generally well-tolerated, with frequency of treatment-emergent adverse events similar between study arms. The number of patients who died totaled eight, four each between active and placebo. In the Brilacidin group, one patient who died did not complete the treatment regimen and withdrew from the study. The overall mortality rate (6.67%) in the trial was approximately one-half of what is typically observed in this patient population.
I agree with you here. It would have been nice to have a further detailed PR today concerning those that walk out of the hospital in good condition, those that remain in the hospital and their condition, those that died of other causes altogether. Again this is supposed to have been an AnitViral use here but this was a test for moderate to severe related patients. That is a high hurdle to jump over here as now we have seen. But to me the negligence of the PR in not pronouncing any good news about these tests leaved me puzzled. Not enough information and the wording leaves the reader to believe nothing good came from this testing. Which is not great of course, see the PPS now. Be that as it may I was here solely as a small investor to hope some good for humanity would come from this so I for one am sitting tight here. Other good things may come forth here and I am ready for that news to come. GLTA here. By the way for those shorts here who bought recently this is the OTC and is really a buyer beware stock. Thanks. Wish the PR had other news it did but not really related.
Patience all this is not McDonald's you're burger is not quite ready for you yet. GO IPIX.......................
A couple of reminders here for longs and newcomers to IPIX Know what we own folks. Do not lose faith by any negative posters here. Its all good. Gee why would the Government want to check how Brilacidin will perform against these others virus’s?? Things that make you go hmmmmm…………………….. But we know why don’t we folks. Good night all.
+++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
The Company is also pleased to report Brilacidin has been shipped to two academic laboratories for planned in vitro testing of Brilacidin in over 20 acutely infectious viruses, including Ebola, Marburg, Nipah, West Nile and Zika, through a collaboration with U.S. government scientists. The goal of this testing is to further inform the spectrum of Brilacidin’s antiviral properties.
+++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
Today the Company announced and anticipates reporting topline results the week of November 8th from its Phase 2 clinical trial of Brilacidin for treatment of moderate-to-severe COVID-19 in hospitalized patients
+++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
Dr Degrado, IPIX science advisor, is acknowledged by his peers as a leading researcher in the field of proteins, peptides
and defensins as well as defensin based pharmaceuticals.
Brilacidin is based structurally on a defensin peptide, Magainin. Attempts to make Magainin a therapeutic failed to to the structural weakness in its peptide core.
Dr Degrado and his team used biochemical and supercomputer enhancement to produce a new pharmacologically stable compound with superior antibiotic, anti-inflammatory and now antiviral capabilities, Brilacidin.
Having Dr DeGrado give a portion of a named lecture in his field is an honor .
Having Dr Degrado as IPIX's scientific advisor gives IPIX and Brilacidin scientific and academic credibility that is priceless.
Brilacidin research is just beginning to open its multiple possible uses as a pharmacologic agent.
Remember shareholders this evening it is morning in Russia/Moscow/St. Pete areas that is. So they may have some news perhaps?
A shout out to you DrBones, much appreciated. GO IPIX.........
https://rupharma.com/arbidol/
I had never heard of this before.
Anyway GO IPIX..........
Anyone here heard of this drug.
https://en.wikipedia.org/wiki/Umifenovir
Umifenovir, sold under the brand name Arbidol, is an antiviral medication for the treatment of influenza infection used in Russia[4] and China. The drug is manufactured by Pharmstandard (Russian: ????????????). Russian and China studies have shown it to be effective and it is approved in both countries while, it is not approved by the US FDA for the treatment or prevention of influenza because it was never applied for FDA approval since the drug company is in Russia not the US.[5]
Chemically, umifenovir features an indole core, functionalized at all but one positions with different substituents. The drug has been shown in studies to inhibit viral entry into target cells [6] and stimulate the immune response.
Umifenovir is manufactured and made available as tablets, capsules and syrup
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187825/