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Dont be like that Donny. They coming soon.
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Columbus Day is starting to look not so bad.
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B-COVID TLD isnt late. It always takes about two months.
NWBO on the other hand....don't compare the two. Something stinks over there.
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$2.50 within 25 days? I better buy some.
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Nah, you'll get data before Halloween. Im still thinking September is still a little more likely than Oct.
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It is all noise and yammering on both sides.
Does it work?
How much better than the SOC is it?
We should know in the next month or two. Hopefully its good and Brilacidin becomes the COVID drug of choice in 2023.
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I'm not even sure you guys are standing in the same line reading those two posts.
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I'll bet you a Zubr we get them before Halloween.
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It's a multinational trial as well. It's also possible terms are being discussed. I'm not worrying about results until after Halloween. Any time before then is icing on the cake.
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It's not peripheral neuropathy. Its Paresthesia causes by ion channel stimulation.
Blood pressure effects are easily managed in a hospital setting.
This is a moderate-severe covid drug. The side effects arent going to be an impediment if efficacy is high.
Dosage was raised from 3 to 5 days mid trial.
But you know all this already.
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Becuase Brilacidin causes temporary numbness and tingling. When you eliminate N/T Brilacidin had 4 AEs vs Daptomycin's 13 AEs.
Of all the AEs a COVID drug might have, tingles is probably the most pleasant.
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Yep, I consider it a coin toss because I feel we have little way to know how much effect we will have on COVID outcomes. I think it is very likely there will be some improvement. Hitting that big money threshold though? 50-50 with the data I have available.
Others may think its higher or lower which is fine.
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He also neglects to mention that Placebo had similar levels of AEs.
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Well, yeah, if we fail to demonstrate a significant improvement over the SOC in this trial it will be a proverbial "kick in the balls" for shareholders.
That goes without saying. Here's to hoping our data meets the threshold required for a lucrative partnership or buyout.
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I agree with this. With ~60 patients dosed we're looking for significant effect well beyond a 10% improvement over the SOC. The SOC with Remdesivir does so little that a 10% improvement would be considered noise.
I think we'll be looking for 30% reductions in duration and mortality vs SOC as a starting point. Much lower than that and we would probably have to gamble on a phase 2b before being able to secure good deal terms.
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It will be like an uppercut to the chin. Any day now Leo!
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All things are possible in IPIX land.
Even success.
I think.
Or maybe just hope.
L'Shanah Tovah to all my tribesmen out there.
Well that's good.
Also shows our CEO is wise to raise cash during the relative strength of the volume and price we have seen over the last few months. I'll be most of that August number was raised the last two weeks of July.
It's good to see him shed that timid CFO concern about dilution. Cash makes the wheels of progress turn Leo! Good raising it!
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That's the fun part about this stock.
It may be your last chance to buy at $0.28.
It may just as easily be your last chance to sell at $0.28.
The thrill of the OTC knife edge.
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Interesting board. I'm surprised wsbc hasn't plastered me up there yet.
I'd love to know if he told the Synagogue to sell them immediately or to hold them until further notice.
That might be one of the most valuable pieces of intel one could get with regard to IPIX. We'll never know though.
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I thought I was Marcin from Poland. Now I'm Leo Ehrlich?
Neither is the case but you're welcome to believe what you like. I just wanted to make sure you (and anyone who thought your ridiculous claim is credible) heard it from the horses mouth that I am not he.
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"If you spend too much time looking in the rearview mirror you may miss the turn." - Anonymous IPIX investor
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Why are you so obsessed with spending valuable cash on high risk drugs when we have a very substantial chance of success in Brilacidin? We will need that cash to ramp manufacturing and start phase 3 B-COVID or, if B-COVID fails, to begin advancing a very lucrative UC/IBD indication.
No trial we have run is statistically meaningless if the results were good enough.
They're definitely going to get paid big government cheddar.
The window of opportunity for IPIX could close at any time. Quick action to monetize results and bring the company back from the brink is essential here.
People who scoff at a $3 buyout underestimate the danger here. We will be quite fortunate if that is our final result.
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Because we get new eyes on this board every day. There are times throughout the day when I am bored enough to chime in.
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Well we have to make some assumptions about an investment...we are after all essentially attempting to predict the future. I didn't mean to imply that I factually know the current balance of the company's cash if it was read that way.
But if you want to get really want to talk semantics...
"It is still good to have that $10M on hand even before money starts being raised."
There is no factual statement made about how much the company has, only that it is good to have that $10M (or $12M or $14M) that we had as of the last filing on hand as a contingency. That doesn't mean it's still there, but given the lack employees, trial starts, and other announcements I'm assuming most of it is.
Compare that to Hugon's statement which I objected to:
"every time it drops in share price he just issues him and his cronies another batch of 20m at .01"
Every time the stock price drops (multiple times per day) he issues himself and his cronies a batch of 20M shares at $0.01? That's a lot of false factual statements about past events. Obviously Hugon's claim is patently and invariably false.
Of course "every time" is him being hyperbolic though frankly I'm unsure the second half of that statement has happened even one time. I'm not motivated enough to go look up the terms of the sweeteners/warrants/options of the various financing deals the company has undertaken but odds are there was never a "batch of 20M at .01".
My saying it's good for Leo to be conservative and keep most of the money from the last filing on hand for contingency (he may not have) is just not the same.
If my imprecise language caused you or anyone else to infer otherwise you have my apologies. You also have my gratitude for keeping me honest on my assumption. Your penchant for linguistic fidelity is under appreciated around here but you have my appreciation even when it is pointed in my direction.
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I doubt the database is even locked yet so no, nobody knows nothing.
If something leaks, good or bad, you'll see this stock fly given our anemic volume.
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There's nothing passive about my aggression. I think Leo has been doing a good job since COVID hit in his handling of the company. However, for the five years prior to that I feel he has managed this company extremely foolishly. I give him the benefit of the doubt and attribute it to inexperience rather than malevolence but man...
That said I think Brilacidin has extreme potential in a number of indications and I hope we've lucked into a pathway to market for a number of them thanks almost entirely to the COVID pandemic.
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I was being conservative. We also wouldn't spend down to $0...things were getting pretty scary here with six-figures of cash in the bank prior to COVID.
I'm comfortable with "$10M-15M on hand" if that's more to your taste. Probably a reasonable range barring a large expense or a large raise.
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It is still good to have that $10M on hand even before money starts being raised. There really is no telling what the IPIX shareprice will do on results.
Leo is wise to be conservative here. He knows to not bank on share price appreciation again. Slow and steady our wise leader goes.
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Why are you just making up things as if they are facts?
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Well you can be 100% sure a True Long is not selling. A True Long does not sell until Leo does. Its axiomatic.
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Likely because we have to make decisions based on limited resources going forward. If B-COVID fails we need the money for UC. If B-COVID succeeds we're going to need to cash to expedite things until a partnership or grant can be achieved.
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Very true words.
“If someone can prove me wrong and show me my mistake in any thought or action, I shall gladly change. I seek the truth, which never harmed anyone: the harm is to persist in one's own self-deception and ignorance.” - Marcus Aurelius
The key is learning the truth before everyone else does. That's how you make money...or preserve what is left of it. One's own ignorance and self-deception is how you ride a stock from $3.50 down to $0.29 and buy more along the way. It has been a costly lesson for me...one that I will try to avoid in the future.
And yet I persist, hoping that somehow Brilacidin pulls through in this trial and launches us to new highs. Clinging to the delusion for a just a bit longer...this trial will be the last one I hold out hope for. Unless this one fails...then B-UC. There's always hope. Right? Right?!?!
Go IPIX!